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J Clin Microbiol. Jun 1982; 15(6): 1167–1168.
PMCID: PMC272275

Rapid detection in spinal fluid of beta-lactamase produced by ampicillin-resistant Haemophilus influenzae.


The chromogenic cephalosporin nitrocefin was used to detect the presence of beta-lactamase in cerebrospinal fluid of patients suffering from ampicillin-resistant Haemophilus influenzae meningitis. Five samples of spinal fluid containing ampicillin-resistant isolates were studied, and all had beta-lactamase activity. When samples of spinal fluid containing 33 ampicillin-sensitive isolates and 234 sterile specimens were tested, no beta-lactamase activity was detected.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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