My NCBISign In
Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum
Neekesh V Dharia, Amar Bir Singh Sidhu, María Belén Cassera, Scott J Westenberger, Selina ER Bopp, Rich T Eastman, David Plouffe, Serge Batalov, Daniel J Park, Sarah K Volkman, Dyann F Wirth, Yingyao Zhou, David A Fidock, Elizabeth A Winzeler
Genome Biol. 2009; 10(2): R21. Published online 2009 February 13. doi: 10.1186/gb-2009-10-2-r21
PMCID:
PMC2688282
Abstract Full Text PDF–1.7M Supplementary Material

Is Cited by the Following 35 Articles in this Archive:

Application of Genomics to Field Investigations of Malaria by the International Centers for Excellence in Malaria Research
Sarah K. Volkman, Daouda Ndiaye, Mahamadou Diakite, Ousmane Koita, Davis Nwakanma, Rachel Daniels, Danny Park, Dan Neafsey, Marc Muskavitch, Don Krogstad, Pardis Sabeti, Dan Hartl, Dyann Wirth
Acta Trop. Author manuscript; available in PMC 2013 March 1.
Published in final edited form as: Acta Trop. 2012 March; 121(3): 324–332. Published online 2011 December 13. doi: 10.1016/j.actatropica.2011.12.002
PMCID:
PMC3294120
Free in PMC on 2013/03/01
Improving Malaria Control in West Africa: Interruption of Transmission as a Paradigm Shift
Seydou O. Doumbia, Daouda Ndiaye, Ousmane A. Koita, Mahamadou Diakité, Davis Nwakanma, Mamadou Coulibaly, Sekou F. Traoré, Joseph Keating, Danny A. Milner, Jr., Jean-Louis Ndiaye, Papa Diogoye Sene, Ambroise Ahouidi, Tandakha N. Dieye, Oumar Gaye, Joseph Okebe, Serign J. Ceesay, Alfred Ngwa, Eniyou C. Oriero, Lassana Konaté, Ngayo Sy, Musa Jawara, Ousmane Faye, Moussa Kéita, Moussa Cissé, Nafomon Sogoba, Belco Poudiougou, Sory Diawara, Lansana Sangaré, Tinzana Coulibaly, Ibrahima Seck, Ismaela Abubakar, Jules Gomis, Frances J. Mather, Aliou Sissako, Ayouba Diarra, Balla Kandeh, Christopher Whalen, Brian Moyer, Obinna Nnedu, Oumar Thiero, Amy K. Bei, Rachel Daniels, Kazutoyo Miura, Carole A. Long, Rick M. Fairhurst, Manoj Duraisingh, Marc A.T. Muskavitch, Umberto D’Alessandro, David J. Conway, Sarah K. Volkman, Clarissa Valim, Dyann F. Wirth, Donald J. Krogstad
Acta Trop. Author manuscript; available in PMC 2013 March 1.
Published in final edited form as: Acta Trop. 2012 March; 121(3): 175–183. Published online 2011 November 28. doi: 10.1016/j.actatropica.2011.11.009
PMCID:
PMC3294075
Free in PMC on 2013/03/01
An Erythrocyte Cytoskeleton-Binding Motif in Exported Plasmodium falciparum Proteins
Geoffrey K. Kilili, Douglas J. LaCount
Eukaryot Cell. 2011 November; 10(11): 1439–1447. doi: 10.1128/EC.05180-11
PMCID:
PMC3209045
Abstract Full Text PDF–771K Supplementary Material
Identifying apicoplast-targeting antimalarials using high-throughput compatible approaches
Eric H. Ekland, Jessica Schneider, David A. Fidock
FASEB J. 2011 October; 25(10): 3583–3593. doi: 10.1096/fj.11-187401
PMCID:
PMC3177575
Free in PMC on 2012/10/01
The landscape of inherited and de novo copy number variants in a plasmodium falciparum genetic cross
Upeka Samarakoon, Joseph M Gonzales, Jigar J Patel, Asako Tan, Lisa Checkley, Michael T Ferdig
BMC Genomics. 2011; 12: 457. Published online 2011 September 22. doi: 10.1186/1471-2164-12-457
PMCID:
PMC3191341
Abstract Full Text PDF–1.9M Supplementary Material
A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor
Tae-gyu Nam, Case W. McNamara, Selina Bopp, Neekesh V. Dharia, Stephan Meister, Ghislain M.C. Bonamy, David M. Plouffe, Nobutaka Kato, Susan McCormack, Badry Bursulaya, Hangjun Ke, Akhil B. Vaidya, Peter G. Schultz, Elizabeth A. Winzeler
ACS Chem Biol. Author manuscript; available in PMC 2012 November 18.
Published in final edited form as: ACS Chem Biol. 2011 November 18; 6(11): 1214–1222. Published online 2011 September 8. doi: 10.1021/cb200105d
PMCID:
PMC3220786
Free in PMC on 2012/11/18
Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum
Ellen Yeh, Joseph L. DeRisi
PLoS Biol. 2011 August; 9(8): e1001138. Published online 2011 August 30. doi: 10.1371/journal.pbio.1001138
PMCID:
PMC3166167
Abstract Full Text PDF–1.5M Supplementary Material
Challenges and Prospects for Malaria Elimination in the Southern Africa Region
William J. Moss, Douglas E. Norris, Sungano Mharakurwa, Alan Scott, Modest Mulenga, Peter R. Mason, James Chipeta, Philip E. Thuma
Acta Trop. Author manuscript; available in PMC 2013 March 1.
Published in final edited form as: Acta Trop. 2012 March; 121(3): 207–211. Published online 2011 August 19. doi: 10.1016/j.actatropica.2011.06.019
PMCID:
PMC3248614
Free in PMC on 2013/03/01
Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription
Sachel Mok, Mallika Imwong, Margaret J Mackinnon, Joan Sim, Ramya Ramadoss, Poravuth Yi, Mayfong Mayxay, Kesinee Chotivanich, Kek-Yee Liong, Bruce Russell, Duong Socheat, Paul N Newton, Nicholas PJ Day, Nicholas J White, Peter R Preiser, François Nosten, Arjen M Dondorp, Zbynek Bozdech
BMC Genomics. 2011; 12: 391. Published online 2011 August 3. doi: 10.1186/1471-2164-12-391
PMCID:
PMC3163569
Abstract Full Text PDF–4.2M Supplementary Material
Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured Plasmodium falciparum Parasites
Richard T. Eastman, Neekesh V. Dharia, Elizabeth A. Winzeler, David A. Fidock
Antimicrob Agents Chemother. 2011 August; 55(8): 3908–3916. doi: 10.1128/AAC.01793-10
PMCID:
PMC3147642
Abstract Full Text PDF–999K Supplementary Material
Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii
Sethu C. Nair, Carrie F. Brooks, Christopher D. Goodman, Angelika Strurm, Geoffrey I. McFadden, Sandeep Sundriyal, Justin L. Anglin, Yongcheng Song, Silvia N.J. Moreno, Boris Striepen
J Exp Med. 2011 July 4; 208(7): 1547–1559. doi: 10.1084/jem.20110039
Correction in:
J Exp Med. 2012 May 7; 209(5): 1051.
PMCID:
PMC3135366
Abstract Full Text PDF–2.6M Supplementary Material
Fosmidomycin Uptake into Plasmodium and Babesia-Infected Erythrocytes Is Facilitated by Parasite-Induced New Permeability Pathways
Stefan Baumeister, Jochen Wiesner, Armin Reichenberg, Martin Hintz, Sven Bietz, Omar S. Harb, David S. Roos, Maximilian Kordes, Johannes Friesen, Kai Matuschewski, Klaus Lingelbach, Hassan Jomaa, Frank Seeber
PLoS One. 2011; 6(5): e19334. Published online 2011 May 4. doi: 10.1371/journal.pone.0019334
PMCID:
PMC3087763
Abstract Full Text PDF–1.2M Supplementary Material
Identification and Functional Validation of the Novel Antimalarial Resistance Locus PF10_0355 in Plasmodium falciparum
Daria Van Tyne, Daniel J. Park, Stephen F. Schaffner, Daniel E. Neafsey, Elaine Angelino, Joseph F. Cortese, Kayla G. Barnes, David M. Rosen, Amanda K. Lukens, Rachel F. Daniels, Danny A. Milner, Jr., Charles A. Johnson, Ilya Shlyakhter, Sharon R. Grossman, Justin S. Becker, Daniel Yamins, Elinor K. Karlsson, Daouda Ndiaye, Ousmane Sarr, Souleymane Mboup, Christian Happi, Nicholas A. Furlotte, Eleazar Eskin, Hyun Min Kang, Daniel L. Hartl, Bruce W. Birren, Roger C. Wiegand, Eric S. Lander, Dyann F. Wirth, Sarah K. Volkman, Pardis C. Sabeti
PLoS Genet. 2011 April; 7(4): e1001383. Published online 2011 April 21. doi: 10.1371/journal.pgen.1001383
PMCID:
PMC3080868
Abstract Full Text PDF–1.0M Supplementary Material
A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling
Baichen Zhang, Kristin M. Watts, Dana Hodge, Lisa M. Kemp, David A. Hunstad, Leslie M. Hicks, Audrey R. Odom
Biochemistry. Author manuscript; available in PMC 2012 May 3.
Published in final edited form as: Biochemistry. 2011 May 3; 50(17): 3570–3577. Published online 2011 April 11. doi: 10.1021/bi200113y
PMCID:
PMC3082593
Abstract Full Text PDF–548K Supplementary Material
An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations
John C Tan, Becky A Miller, Asako Tan, Jigar J Patel, Ian H Cheeseman, Tim JC Anderson, Magnus Manske, Gareth Maslen, Dominic P Kwiatkowski, Michael T Ferdig
Genome Biol. 2011; 12(4): R35. Published online 2011 April 8. doi: 10.1186/gb-2011-12-4-r35
PMCID:
PMC3218861
Abstract Full Text PDF–1011K Supplementary Material
FORS-D Analysis in P. falciparum can Differentiate Classes of Genes Under Selection
Atish Kathpal, Balakota Reddy Patakottu, Swati Patankar
Evol Bioinform Online. 2011; 7: 21–29. Published online 2011 March 20. doi: 10.4137/EBO.S6609
PMCID:
PMC3072625
Abstract Full Text PDF–538K
High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum
Upeka Samarakoon, Allison Regier, Asako Tan, Brian A Desany, Brendan Collins, John C Tan, Scott J Emrich, Michael T Ferdig
BMC Genomics. 2011; 12: 116. Published online 2011 February 17. doi: 10.1186/1471-2164-12-116
PMCID:
PMC3055840
Abstract Full Text PDF–919K Supplementary Material
Validation of isoleucine utilization targets in Plasmodium falciparum
Eva S. Istvan, Neekesh V. Dharia, Selina E. Bopp, Ilya Gluzman, Elizabeth A. Winzeler, Daniel E. Goldberg
Proc Natl Acad Sci U S A. 2011 January 25; 108(4): 1627–1632. Published online 2011 January 4. doi: 10.1073/pnas.1011560108
PMCID:
PMC3029723
Abstract Full Text PDF–1.6M Supplementary Material
How can we identify parasite genes that underlie antimalarial drug resistance?
Tim Anderson, Standwell Nkhoma, Andrea Ecker, David Fidock
Pharmacogenomics. Author manuscript; available in PMC 2011 November 1.
Published in final edited form as: Pharmacogenomics. 2011 January; 12(1): 59–85. doi: 10.2217/pgs.10.165
PMCID:
PMC3148835
Abstract Full Text PDF–1.7M
Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites
Neekesh V. Dharia, David Plouffe, Selina E.R. Bopp, Gonzalo E. González-Páez, Carmen Lucas, Carola Salas, Valeria Soberon, Badry Bursulaya, Tadeusz J. Kochel, David J. Bacon, Elizabeth A. Winzeler
Genome Res. 2010 November; 20(11): 1534–1544. doi: 10.1101/gr.105163.110
PMCID:
PMC2963817
Abstract Full Text PDF–694K
Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes
Neekesh V. Dharia, A. Taylor Bright, Scott J. Westenberger, S. Whitney Barnes, Serge Batalov, Kelli Kuhen, Rachel Borboa, Glenn C. Federe, Colleen M. McClean, Joseph M. Vinetz, Victor Neyra, Alejandro Llanos-Cuentas, John W. Barnwell, John R. Walker, Elizabeth A. Winzeler
Proc Natl Acad Sci U S A. 2010 November 16; 107(46): 20045–20050. Published online 2010 October 29. doi: 10.1073/pnas.1003776107
PMCID:
PMC2993397
Abstract Full Text PDF–608K Supplementary Material
A novel multifunctional oligonucleotide microarray for Toxoplasma gondii
Amit Bahl, Paul H Davis, Michael Behnke, Florence Dzierszinski, Manjunatha Jagalur, Feng Chen, Dhanasekaran Shanmugam, Michael W White, David Kulp, David S Roos
BMC Genomics. 2010; 11: 603. Published online 2010 October 25. doi: 10.1186/1471-2164-11-603
PMCID:
PMC3017859
Abstract Full Text PDF–2.2M Supplementary Material
An Adaptable Two-Color Flow Cytometric Assay to Quantitate the Invasion of Erythrocytes by Plasmodium falciparum Parasites
Michel Theron, Richard L Hesketh, Sathish Subramanian, Julian C Rayner
Cytometry A. 2010 November; 77A(11): 1067–1074. Published online 2010 September 24. doi: 10.1002/cyto.a.20972
PMCID:
PMC3047707
Abstract Full Text PDF–593K Supplementary Material
Identification of inhibitors for putative malaria drug targets amongst novel antimalarial compounds
Gregory J. Crowther, Alberto J. Napuli, James H. Gilligan, Kerstin Gagaring, Rachel Borboa, Carolyn Francek, Zhong Chen, Eleanor F. Dagostino, Justin B. Stockmyer, Yu Wang, Philip P. Rodenbough, Lisa J. Castaneda, David J. Leibly, Janhavi Bhandari, Michael H. Gelb, Achim Brinker, Ingo Engels, Jennifer Taylor, Arnab K. Chatterjee, Pascal Fantauzzi, Richard J. Glynne, Wesley C. Van Voorhis, Kelli L. Kuhen
Mol Biochem Parasitol. Author manuscript; available in PMC 2012 January 1.
Published in final edited form as: Mol Biochem Parasitol. 2011 January; 175(1): 21–29. Published online 2010 September 15. doi: 10.1016/j.molbiopara.2010.08.005
PMCID:
PMC3108854
Abstract Full Text PDF–417K Supplementary Material
Spiroindolones, a new and potent chemotype for the treatment of malaria
Matthias Rottmann, Case McNamara, Bryan K. S. Yeung, Marcus C. S. Lee, Bin Zou, Bruce Russell, Patrick Seitz, David M. Plouffe, Neekesh V. Dharia, Jocelyn Tan, Steven B. Cohen, Kathryn R. Spencer, Gonzalo E. González-Páez, Suresh B. Lakshminarayana, Anne Goh, Rossarin Suwanarusk, Tim Jegla, Esther K. Schmitt, Hans-Peter Beck, Reto Brun, Francois Nosten, Laurent Renia, Veronique Dartois, Thomas H. Keller, David A. Fidock, Elizabeth A. Winzeler, Thierry T. Diagana
Science. Author manuscript; available in PMC 2011 September 3.
Published in final edited form as: Science. 2010 September 3; 329(5996): 1175–1180. doi: 10.1126/science.1193225
PMCID:
PMC3050001
Abstract Full Text PDF–1.7M Supplementary Material
Recent Progress in Functional Genomic Research in Plasmodium falciparum
Jianbing Mu, Karl B Seydel, Adam Bates, Xin-Zhuan Su
Curr Genomics. 2010 June; 11(4): 279–286. doi: 10.2174/138920210791233081
PMCID:
PMC2930667
Abstract Full Text PDF–182K
An update on the rapid advances in malaria parasite cell biology
Isabelle Coppens, David J. Sullivan, Sean T. Prigge
Trends Parasitol. Author manuscript; available in PMC 2011 June 1.
Published in final edited form as: Trends Parasitol. 2010 June; 26(6): 305–310. Published online 2010 April 9. doi: 10.1016/j.pt.2010.03.007
PMCID:
PMC2883679
Abstract Full Text PDF–288K
Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs
Jianbing Mu, Rachel A. Myers, Hongying Jiang, Shengfa Liu, Stacy Ricklefs, Michael Waisberg, Kesinee Chotivanich, Polrat Wilairata, Srivicha Krudsood, Nicholas J. White, Rachanee Udomsangpetch, Liwang Cui, May Ho, Fengzheng Ou, Haibo Li, Jiangping Song, Guoqiao Li, Xinhua Wang, Suon Seila, Sreng Sokunthea, Duong Socheat, Daniel E. Sturdevant, Stephen F. Porcella, Rick M. Fairhurst, Thomas E. Wellems, Philip Awadalla, Xin-zhuan Su
Nat Genet. Author manuscript; available in PMC 2010 September 1.
Published in final edited form as: Nat Genet. 2010 March; 42(3): 268–271. Published online 2010 January 31. doi: 10.1038/ng.528
PMCID:
PMC2828519
Abstract Full Text PDF–1.2M Supplementary Material
Genome-wide nucleosome mapping of Plasmodium falciparum reveals histone-rich coding and histone-poor intergenic regions and chromatin remodeling of core and subtelomeric genes
Scott J Westenberger, Long Cui, Neekesh Dharia, Elizabeth Winzeler, Liwang Cui
BMC Genomics. 2009; 10: 610. Published online 2009 December 16. doi: 10.1186/1471-2164-10-610
PMCID:
PMC2801526
Abstract Full Text PDF–2.9M Supplementary Material
Industrial fuel ethanol yeasts contain adaptive copy number changes in genes involved in vitamin B1 and B6 biosynthesis
Boris U. Stambuk, Barbara Dunn, Sergio L. Alves, Jr, Eduarda H. Duval, Gavin Sherlock
Genome Res. 2009 December; 19(12): 2271–2278. doi: 10.1101/gr.094276.109
PMCID:
PMC2792166
Abstract Full Text PDF–476K
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