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J Clin Microbiol. Nov 1988; 26(11): 2432–2433.
PMCID: PMC266909

Clinical aspects and usefulness of indirect absorbed immunofluorescence for diagnosis of yaws in Central Africa.

Abstract

The incidence of yaws in 533 pygmies from the Central African Republic was surveyed. It appeared that there is still an impressive incidence of yaws in pygmy children who have poor hygiene. Laboratory investigations showed that the Treponema pallidum hemagglutination assay is often negative during the first stage of the disease, while the fluorescent treponemal antibody absorption test is positive and, thus, more sensitive.

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Selected References

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  • Cirera P, Palisson MJ, Pinerd G, Jaeger G. La sérologie tréponémique dans une population Pygmée Bi-Aka centrafricaine. Bull Soc Pathol Exot Filiales. 1977 Jan-Feb;70(1):32–36. [PubMed]
  • Deacon WE, Lucas JB, Price EV. Fluorescent treponemal antibody-absorption (FTA-ABS) test for syphilis. JAMA. 1966 Nov 7;198(6):624–628. [PubMed]
  • YOBS AR, BROWN L, HUNTER EF. FLUORESCENT ANTIBODY TECHNIQUE IN EARLY SYPHILIS; AS APPLIED TO THE DEMONSTRATION OF T PALLIDUM IN LESIONS IN THE RABBIT AND IN THE HUMAN. Arch Pathol. 1964 Feb;77:220–225. [PubMed]

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