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APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA
Rebecca A Russell, Michael D Moore, Wei-Shau Hu, Vinay K Pathak
Retrovirology. 2009; 6: 16. Published online 2009 February 13. doi: 10.1186/1742-4690-6-16
PMCID:
PMC2657108
Abstract Full Text PDF–397K

Is Cited by the Following 14 Articles in this Archive:

The Role of Amino-Terminal Sequences in Cellular Localization and Antiviral Activity of APOBEC3B
Vladimir Pak, Gisela Heidecker, Vinay K. Pathak, David Derse
J Virol. 2011 September; 85(17): 8538–8547. doi: 10.1128/JVI.02645-10
PMCID:
PMC3165795
Abstract Full Text PDF–1.3M
Local Sequence Targeting in the AID/APOBEC Family Differentially Impacts Retroviral Restriction and Antibody Diversification
Rahul M. Kohli, Robert W. Maul, Amy F. Guminski, Rhonda L. McClure, Kiran S. Gajula, Huseyin Saribasak, Moira A. McMahon, Robert F. Siliciano, Patricia J. Gearhart, James T. Stivers
J Biol Chem. 2010 December 24; 285(52): 40956–40964. Published online 2010 October 6. doi: 10.1074/jbc.M110.177402
PMCID:
PMC3003395
Abstract Full Text Supplementary Material
HIV-1 Continues To Replicate and Evolve in Patients with Natural Control of HIV Infection
Helene Mens, Mary Kearney, Ann Wiegand, Wei Shao, Kristian Schønning, Jan Gerstoft, Niels Obel, Frank Maldarelli, John W. Mellors, Thomas Benfield, John M. Coffin
J Virol. 2010 December; 84(24): 12971–12981. Published online 2010 October 6. doi: 10.1128/JVI.00387-10
PMCID:
PMC3004307
Abstract Full Text PDF–841K Supplementary Material
Differential Anti-APOBEC3G Activity of HIV-1 Vif Proteins Derived from Different Subtypes
Yukie Iwabu, Masanobu Kinomoto, Masashi Tatsumi, Hideaki Fujita, Mari Shimura, Yoshitaka Tanaka, Yukihito Ishizaka, David Nolan, Simon Mallal, Tetsutaro Sata, Kenzo Tokunaga
J Biol Chem. 2010 November 12; 285(46): 35350–35358. Published online 2010 September 10. doi: 10.1074/jbc.M110.173286
PMCID:
PMC2975159
Abstract Full Text Supplementary Material
Comparison of the Replication and Persistence of Simian-Human Immunodeficiency Viruses Expressing Vif Proteins with Mutation of the SLQYLA or HCCH Domains in Macaques
Kimberly Schmitt, M. Sarah Hill, Zhenqian Liu, Autumn Ruiz, Nathan Culley, David M. Pinson, Edward B. Stephens
Virology. Author manuscript; available in PMC 2011 September 1.
Published in final edited form as: Virology. 2010 September 1; 404(2): 187–203. doi: 10.1016/j.virol.2010.04.017
PMCID:
PMC2974619
Abstract Full Text PDF–2.8M
Stably Expressed APOBEC3F Has Negligible Antiviral Activity
Eri Miyagi, Charles R. Brown, Sandrine Opi, Mohammad Khan, Ritu Goila-Gaur, Sandra Kao, Robert C. Walker, Jr., Vanessa Hirsch, Klaus Strebel
J Virol. 2010 November; 84(21): 11067–11075. Published online 2010 August 11. doi: 10.1128/JVI.01249-10
PMCID:
PMC2953157
Abstract Full Text PDF–1.2M
Remarkable Lethal G-to-A Mutations in vif-Proficient HIV-1 Provirus by Individual APOBEC3 Proteins in Humanized Mice
Kei Sato, Taisuke Izumi, Naoko Misawa, Tomoko Kobayashi, Yoshiki Yamashita, Masahide Ohmichi, Mamoru Ito, Akifumi Takaori-Kondo, Yoshio Koyanagi
J Virol. 2010 September; 84(18): 9546–9556. Published online 2010 July 7. doi: 10.1128/JVI.00823-10
PMCID:
PMC2937654
Abstract Full Text PDF–1.6M Supplementary Material
HIV-1 Vif Versus the APOBEC3 Cytidine Deaminases: An Intracellular Duel Between Pathogen and Host Restriction Factors
Silke Wissing, Nicole L. K. Galloway, Warner C. Greene
Mol Aspects Med. Author manuscript; available in PMC 2011 October 1.
Published in final edited form as: Mol Aspects Med. 2010 October; 31(5): 383–397. Published online 2010 June 9. doi: 10.1016/j.mam.2010.06.001
PMCID:
PMC2967609
Abstract Full Text PDF–948K
APOBEC3G Contributes to HIV-1 Variation through Sublethal Mutagenesis
Holly A. Sadler, Mark D. Stenglein, Reuben S. Harris, Louis M. Mansky
J Virol. 2010 July; 84(14): 7396–7404. Published online 2010 May 12. doi: 10.1128/JVI.00056-10
PMCID:
PMC2898230
Abstract Full Text PDF–1.8M
Inhibition of Xenotropic Murine Leukemia Virus-Related Virus by APOBEC3 Proteins and Antiviral Drugs
Tobias Paprotka, Narasimhan J. Venkatachari, Chawaree Chaipan, Ryan Burdick, Krista A. Delviks-Frankenberry, Wei-Shau Hu, Vinay K. Pathak
J Virol. 2010 June; 84(11): 5719–5729. Published online 2010 March 24. doi: 10.1128/JVI.00134-10
PMCID:
PMC2876585
Abstract Full Text PDF–1.6M
APOBEC3F and APOBEC3G Inhibit HIV-1 DNA Integration by Different Mechanisms
Jean L. Mbisa, Wei Bu, Vinay K. Pathak
J Virol. 2010 May; 84(10): 5250–5259. Published online 2010 March 10. doi: 10.1128/JVI.02358-09
PMCID:
PMC2863843
Abstract Full Text PDF–1.1M
MULTIPLE WAYS OF TARGETING APOBEC3/VIF INTERACTIONS FOR ANTI-HIV-1 DRUG DEVELOPMENT
Jessica L. Smith, Wei Bu, Ryan C. Burdick, Vinay K. Pathak
Trends Pharmacol Sci. Author manuscript; available in PMC 2010 December 1.
Published in final edited form as: Trends Pharmacol Sci. 2009 December; 30(12): 638–646. doi: 10.1016/j.tips.2009.09.006
PMCID:
PMC2787722
Abstract Full Text PDF–1.1M
Human cellular restriction factors that target HIV-1 replication
Klaus Strebel, Jeremy Luban, Kuan-Teh Jeang
BMC Med. 2009; 7: 48. Published online 2009 September 16. doi: 10.1186/1741-7015-7-48
PMCID:
PMC2759957
Abstract Full Text PDF–2.1M
Likely Role of APOBEC3G-Mediated G-to-A Mutations in HIV-1 Evolution and Drug Resistance
Patric Jern, Rebecca A. Russell, Vinay K. Pathak, John M. Coffin
PLoS Pathog. 2009 April; 5(4): e1000367. Published online 2009 April 3. doi: 10.1371/journal.ppat.1000367
PMCID:
PMC2659435
Abstract Full Text PDF–927K Supplementary Material
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