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Systems medicine: the future of medical genomics and healthcare
Charles Auffray, Zhu Chen, Leroy Hood
Genome Med. 2009; 1(1): 2. Published online 2009 January 20. doi: 10.1186/gm2
PMCID:
PMC2651587
Abstract Full Text PDF–154K

Is Cited by the Following 19 Articles in this Archive:

Rise and Demise of Bioinformatics? Promise and Progress
Christos A. Ouzounis
PLoS Comput Biol. 2012 April; 8(4): e1002487. Published online 2012 April 26. doi: 10.1371/journal.pcbi.1002487
PMCID:
PMC3343106
Abstract Full Text PDF–120K
Narrowing the gap of personalized medicine in emerging countries: the case of multiple endocrine neoplasias in Brazil
Rodrigo A. Toledo, Tomoko Sekiya, Viviane C. Longuini, Flavia L. Coutinho, Delmar M. Lourenço, Jr., Sergio P. A. Toledo
Clinics (Sao Paulo) 2012 April; 67(S1): 3–6. doi: 10.6061/clinics/2012(Sup01)02
PMCID:
PMC3328830
Abstract Full Text PDF–113K
Gene expression and network-based analysis reveals a novel role for hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression
Rotem Ben-Hamo, Sol Efroni
Genome Med. 2011; 3(11): 77. Published online 2011 November 28. doi: 10.1186/gm293
PMCID:
PMC3308032
Abstract Full Text PDF–628K Supplementary Material
Kaviar: an accessible system for testing SNV novelty
Gustavo Glusman, Juan Caballero, Denise E. Mauldin, Leroy Hood, Jared C. Roach
Bioinformatics. 2011 November 15; 27(22): 3216–3217. Published online 2011 September 28. doi: 10.1093/bioinformatics/btr540
PMCID:
PMC3208392
Free in PMC on 2012/11/15
G-DOC: A Systems Medicine Platform for Personalized Oncology
Subha Madhavan, Yuriy Gusev, Michael Harris, David M Tanenbaum, Robinder Gauba, Krithika Bhuvaneshwar, Andrew Shinohara, Kevin Rosso, Lavinia A Carabet, Lei Song, Rebecca B Riggins, Sivanesan Dakshanamurthy, Yue Wang, Stephen W Byers, Robert Clarke, Louis M Weiner
Neoplasia. 2011 September; 13(9): 771–783.
PMCID:
PMC3182270
Abstract Full Text PDF–2.7M
Integrative computational biology for cancer research
Kristen Fortney, Igor Jurisica
Hum Genet. 2011 October; 130(4): 465–481. Published online 2011 April 22. doi: 10.1007/s00439-011-0983-z
PMCID:
PMC3179275
Abstract Full Text PDF–2.3M Supplementary Material
A Network-Based Multi-Target Computational Estimation Scheme for Anticoagulant Activities of Compounds
Qian Li, Xudong Li, Canghai Li, Lirong Chen, Jun Song, Yalin Tang, Xiaojie Xu
PLoS One. 2011; 6(3): e14774. Published online 2011 March 22. doi: 10.1371/journal.pone.0014774
PMCID:
PMC3062543
Abstract Full Text PDF–557K Supplementary Material
Genome Medicine: past, present and future
Charles Auffray, Timothy Caulfield, Muin J Khoury, James R Lupski, Matthias Schwab, Timothy Veenstra
Genome Med. 2011; 3(1): 6. Published online 2011 January 31. doi: 10.1186/gm220
PMCID:
PMC3092091
Full Text PDF–259K
Addiction as a Systems Failure: Focus on Adolescence and Smoking
Ruben D. Baler, Nora D. Volkow
J Am Acad Child Adolesc Psychiatry. Author manuscript; available in PMC 2012 April 1.
Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2011 April; 50(4): 329–339. Published online 2011 January 26. doi: 10.1016/j.jaac.2010.12.008
PMCID:
PMC3215298
Abstract Full Text PDF–79K
Gene Therapy from the perspective of Systems Biology
Feilim Mac Gabhann, Brian H. Annex, Aleksander S. Popel
Curr Opin Mol Ther. Author manuscript; available in PMC 2011 October 1.
Published in final edited form as: Curr Opin Mol Ther. 2010 October; 12(5): 570–577.
PMCID:
PMC3021921
Abstract Full Text PDF–246K
A multiscale systems perspective on cancer, immunotherapy, and Interleukin-12
David J Klinke, II
Mol Cancer. 2010; 9: 242. Published online 2010 September 15. doi: 10.1186/1476-4598-9-242
PMCID:
PMC3243044
Abstract Full Text PDF–2.6M
Predictive, preventive, personalized and participatory medicine: back to the future
Charles Auffray, Dominique Charron, Leroy Hood
Genome Med. 2010; 2(8): 57. Published online 2010 August 26. doi: 10.1186/gm178
PMCID:
PMC2945014
Abstract Full Text PDF–234K
Using next-generation sequencing for high resolution multiplex analysis of copy number variation from nanogram quantities of DNA from formalin-fixed paraffin-embedded specimens
Henry M. Wood, Ornella Belvedere, Caroline Conway, Catherine Daly, Rebecca Chalkley, Melissa Bickerdike, Claire McKinley, Phil Egan, Lisa Ross, Bruce Hayward, Joanne Morgan, Leslie Davidson, Ken MacLennan, Thian K. Ong, Kostas Papagiannopoulos, Ian Cook, David J. Adams, Graham R. Taylor, Pamela Rabbitts
Nucleic Acids Res. 2010 August; 38(14): e151. Published online 2010 June 4. doi: 10.1093/nar/gkq510
PMCID:
PMC2919738
Abstract Full Text PDF–10M Supplementary Material
Coordinated modular functionality and prognostic potential of a heart failure biomarker-driven interaction network
Francisco Azuaje, Yvan Devaux, Daniel R Wagner
BMC Syst Biol. 2010; 4: 60. Published online 2010 May 12. doi: 10.1186/1752-0509-4-60
PMCID:
PMC2890499
Abstract Full Text PDF–1.4M Supplementary Material
Evaluation of an Ontology-anchored Natural Language-based Approach for Asserting Multi-scale Biomolecular Networks for Systems Medicine
Tara B. Borlawsky, Jianrong Li, Lyudmila Shagina, Matthew G. Crowson, Yang Liu, Carol Friedman, Yves A. Lussier
AMIA Summits Transl Sci Proc. 2010; 2010: 6–10. Published online 2010 March 1.
PMCID:
PMC3041541
Abstract Full Text PDF–381K
Systems engineering medicine: engineering the inflammation response to infectious and traumatic challenges
Robert S. Parker, Gilles Clermont
J R Soc Interface. 2010 July 6; 7(48): 989–1013. Published online 2010 February 10. doi: 10.1098/rsif.2009.0517
PMCID:
PMC2880083
Abstract Full Text PDF–741K
Bridging the gap between systems biology and medicine
Gilles Clermont, Charles Auffray, Yves Moreau, David M Rocke, Daniel Dalevi, Devdatt Dubhashi, Dana R Marshall, Peter Raasch, Frank Dehne, Paolo Provero, Jesper Tegner, Bruce J Aronow, Michael A Langston, Mikael Benson
Genome Med. 2009; 1(9): 88. Published online 2009 September 29. doi: 10.1186/gm88
PMCID:
PMC2768995
Abstract Full Text PDF–831K
Systems Biology and Physiome Projects
Aleksander S. Popel, Peter J. Hunter
Wiley Interdiscip Rev Syst Biol Med. Author manuscript; available in PMC 2010 September 19.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2009 Sep–Oct; 1(2): 153–158. doi: 10.1002/wsbm.67
PMCID:
PMC2941734
Full Text PDF–736K
Origins of Systems Biology in William Harvey’s Masterpiece on the Movement of the Heart and the Blood in Animals
Charles Auffray, Denis Noble
Int J Mol Sci. 2009 April; 10(4): 1658–1669. Published online 2009 April 17. doi: 10.3390/ijms10041658
PMCID:
PMC2680639
Abstract Full Text PDF–225K
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