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α-Synuclein and neuronal cell death
Mark R Cookson
Mol Neurodegener. 2009; 4: 9. Published online 2009 February 4. doi: 10.1186/1750-1326-4-9
PMCID:
PMC2646729
Abstract Full Text PDF–690K

Is Cited by the Following 19 Articles in this Archive:

Modeling Parkinson’s Disease Using Induced Pluripotent Stem Cells
Blake Byers, Hsiao-lu Lee, Renee Reijo Pera
Curr Neurol Neurosci Rep. 2012 June; 12(3): 237–242. Published online 2012 April 28. doi: 10.1007/s11910-012-0270-y
PMCID:
PMC3342500
Abstract Full Text PDF–144K
Role of Alpha-Synuclein Protein Levels in Mitochondrial Morphology and Cell Survival in Cell Lines
Min Zhu, Wenwei Li, Chuanzhen Lu
PLoS One. 2012; 7(4): e36377. Published online 2012 April 27. doi: 10.1371/journal.pone.0036377
PMCID:
PMC3338674
Abstract Full Text PDF–623K Supplementary Material
Drosophila Models of Proteinopathies: the Little Fly that Could
Diego E Rincon-Limas, Kurt Jensen, Pedro Fernandez-Funez
Curr Pharm Des. 2012 March; 18(8): 1108–1122. Published online 2012 March. doi: 10.2174/138161212799315894
PMCID:
PMC3290773
Abstract Full Text PDF–350K
α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, and Escherichia coli Exists Predominantly as Disordered Monomer
Bruno Fauvet, Martial K. Mbefo, Mohamed-Bilal Fares, Carole Desobry, Sarah Michael, Mustafa T. Ardah, Elpida Tsika, Philippe Coune, Michel Prudent, Niels Lion, David Eliezer, Darren J. Moore, Bernard Schneider, Patrick Aebischer, Omar M. El-Agnaf, Eliezer Masliah, Hilal A. Lashuel
J Biol Chem. 2012 May 4; 287(19): 15345–15364. Published online 2012 February 7. doi: 10.1074/jbc.M111.318949
PMCID:
PMC3346117
Free in PMC on 2013/05/04
Effect of Single Amino Acid Substitution on Oxidative Modifications of the Parkinson's Disease-Related Protein, DJ-1
Ashraf G. Madian, Jagadish Hindupur, John D. Hulleman, Naomi Diaz-Maldonado, Vartika R. Mishra, Emmanuel Guigard, Cyril M. Kay, Jean-Christophe Rochet, Fred E. Regnier
Mol Cell Proteomics. 2012 February; 11(2): M111.010892. Published online 2011 November 21. doi: 10.1074/mcp.M111.010892
PMCID:
PMC3277756
Free in PMC on 2013/02/01
SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate α-Synuclein and Are Susceptible to Oxidative Stress
Blake Byers, Branden Cord, Ha Nam Nguyen, Birgitt Schüle, Lief Fenno, Patrick C. Lee, Karl Deisseroth, J. William Langston, Renee Reijo Pera, Theo D. Palmer
PLoS One. 2011; 6(11): e26159. Published online 2011 November 16. doi: 10.1371/journal.pone.0026159
PMCID:
PMC3217921
Abstract Full Text PDF–1.1M Supplementary Material
Toll-Like Receptor 4 Promotes α-Synuclein Clearance and Survival of Nigral Dopaminergic Neurons
Nadia Stefanova, Lisa Fellner, Markus Reindl, Eliezer Masliah, Werner Poewe, Gregor K. Wenning
Am J Pathol. 2011 August; 179(2): 954–963. doi: 10.1016/j.ajpath.2011.04.013
PMCID:
PMC3157205
Free in PMC on 2012/08/01
α-Synuclein Interacts with Glucocerebrosidase Providing a Molecular Link between Parkinson and Gaucher Diseases
Thai Leong Yap, James M. Gruschus, Arash Velayati, Wendy Westbroek, Ehud Goldin, Nima Moaven, Ellen Sidransky, Jennifer C. Lee
J Biol Chem. 2011 August 12; 286(32): 28080–28088. Published online 2011 June 8. doi: 10.1074/jbc.M111.237859
PMCID:
PMC3151053
Free in PMC on 2012/08/12
A microRNA embedded AAV alpha-synuclein gene silencing vector for dopaminergic neurons
Ye Han, Christina E. Khodr, Mohan K. Sapru, Jyothi Pedapati, Martha C. Bohn
Brain Res. Author manuscript; available in PMC 2012 April 22.
Published in final edited form as: Brain Res. 2011 April 22; 1386: 15–24. Published online 2011 February 19. doi: 10.1016/j.brainres.2011.02.041
PMCID:
PMC3076891
Abstract Full Text PDF–571K
Specificity and Kinetics of α-Synuclein Binding to Model Membranes Determined with Fluorescent Excited State Intramolecular Proton Transfer (ESIPT) Probe
Volodymyr V. Shvadchak, Lisandro J. Falomir-Lockhart, Dmytro A. Yushchenko, Thomas M. Jovin
J Biol Chem. 2011 April 15; 286(15): 13023–13032. Published online 2011 February 17. doi: 10.1074/jbc.M110.204776
PMCID:
PMC3075648
Abstract Full Text
Defects in Very Long Chain Fatty Acid Synthesis Enhance Alpha-Synuclein Toxicity in a Yeast Model of Parkinson's Disease
Yong Joo Lee, Shaoxiao Wang, Sunny R. Slone, Talene A. Yacoubian, Stephan N. Witt
PLoS One. 2011; 6(1): e15946. Published online 2011 January 11. doi: 10.1371/journal.pone.0015946
PMCID:
PMC3019226
Abstract Full Text PDF–728K
A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions
Sheila M. Fleming, Caitlin K. Mulligan, Franziska Richter, Farzad Mortazavi, Vincent Lemesre, Carmen Frias, Chunni Zhu, Alistair Stewart, Illana Gozes, Bruce Morimoto, Marie-Françoise Chesselet
Mol Cell Neurosci. Author manuscript; available in PMC 2012 March 1.
Published in final edited form as: Mol Cell Neurosci. 2011 March; 46(3): 597–606. Published online 2010 December 27. doi: 10.1016/j.mcn.2010.12.011
PMCID:
PMC3046337
Abstract Full Text PDF–1.9M
Inhibiting α-Synuclein Oligomerization by Stable Cell-Penetrating β-Synuclein Fragments Recovers Phenotype of Parkinson's Disease Model Flies
Ronit Shaltiel-Karyo, Moran Frenkel-Pinter, Nirit Egoz-Matia, Anat Frydman-Marom, Deborah E. Shalev, Daniel Segal, Ehud Gazit
PLoS One. 2010; 5(11): e13863. Published online 2010 November 10. doi: 10.1371/journal.pone.0013863
PMCID:
PMC2978097
Abstract Full Text PDF–1.9M Supplementary Material
Glial Innate Immunity Generated by Non-Aggregated Alpha-Synuclein in Mouse: Differences between Wild-type and Parkinson's Disease-Linked Mutants
Cintia Roodveldt, Adahir Labrador-Garrido, Elena Gonzalez-Rey, Rafael Fernandez-Montesinos, Marta Caro, Christian C. Lachaud, Christopher A. Waudby, Mario Delgado, Christopher M. Dobson, David Pozo
PLoS One. 2010; 5(10): e13481. Published online 2010 October 26. doi: 10.1371/journal.pone.0013481
PMCID:
PMC2964342
Abstract Full Text PDF–2.7M Supplementary Material
α-Synuclein Suppression by Targeted Small Interfering RNA in the Primate Substantia Nigra
Alison L. McCormack, Sally K. Mak, Jaimie M. Henderson, David Bumcrot, Matthew J. Farrer, Donato A. Di Monte
PLoS One. 2010; 5(8): e12122. Published online 2010 August 11. doi: 10.1371/journal.pone.0012122
PMCID:
PMC2920329
Abstract Full Text PDF–1.9M
α-Synuclein sequesters arachidonic acid to modulate SNARE-mediated exocytosis
Frédéric Darios, Violeta Ruipérez, Inmaculada López, Jose Villanueva, Luis M Gutierrez, Bazbek Davletov
EMBO Rep. 2010 July; 11(7): 528–533. Published online 2010 May 21. doi: 10.1038/embor.2010.66
PMCID:
PMC2897113
Abstract Full Text PDF–328K Supplementary Material
Entacapone and Tolcapone, Two Catechol O-Methyltransferase Inhibitors, Block Fibril Formation of α-Synuclein and β-Amyloid and Protect against Amyloid-induced Toxicity
Saviana Di Giovanni, Simona Eleuteri, Katerina E. Paleologou, Guowei Yin, Markus Zweckstetter, Pierre-Alain Carrupt, Hilal A. Lashuel
J Biol Chem. 2010 May 14; 285(20): 14941–14954. Published online 2010 February 11. doi: 10.1074/jbc.M109.080390
PMCID:
PMC2865316
Abstract Full Text
The Divalent Metal Transporter Homologues SMF-1/2 Mediate Dopamine Neuron Sensitivity in Caenorhabditis elegans Models of Manganism and Parkinson Disease
Raja Settivari, Jennifer LeVora, Richard Nass
J Biol Chem. 2009 December 18; 284(51): 35758–35768. Published online 2009 September 30. doi: 10.1074/jbc.M109.051409
PMCID:
PMC2791006
Abstract Full Text
Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice
Sha-Ron Pierre, Marijke AM Lemmens, Maria E Figueiredo-Pereira
J Neuroinflammation. 2009; 6: 18. Published online 2009 July 25. doi: 10.1186/1742-2094-6-18
PMCID:
PMC2724408
Abstract Full Text PDF–937K
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