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PGC-1alpha as modifier of onset age in Huntington disease
Elahe Taherzadeh-Fard, Carsten Saft, Jürgen Andrich, Stefan Wieczorek, Larissa Arning
Mol Neurodegener. 2009; 4: 10. Published online 2009 February 6. doi: 10.1186/1750-1326-4-10
PMCID:
PMC2644307
Abstract Full Text PDF–242K

Is Cited by the Following 12 Articles in this Archive:

Shaping the role of mitochondria in the pathogenesis of Huntington's disease
Veronica Costa, Luca Scorrano
EMBO J. 2012 April 18; 31(8): 1853–1864. Published online 2012 March 23. doi: 10.1038/emboj.2012.65
PMCID:
PMC3343341
Free in PMC on 2013/04/18
Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease
Ashu Johri, Noel Y. Calingasan, Thomas M. Hennessey, Abhijeet Sharma, Lichuan Yang, Elizabeth Wille, Abhishek Chandra, M. Flint Beal
Hum Mol Genet. 2012 March 1; 21(5): 1124–1137. Published online 2011 November 17. doi: 10.1093/hmg/ddr541
PMCID:
PMC3277311
Free in PMC on 2013/03/01
Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease
Joanne Clark, Sonika Reddy, Kangni Zheng, Rebecca A Betensky, David K Simon
BMC Med Genet. 2011; 12: 69. Published online 2011 May 19. doi: 10.1186/1471-2350-12-69
PMCID:
PMC3112073
Abstract Full Text PDF–214K Supplementary Material
PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease
Elahe Taherzadeh-Fard, Carsten Saft, Denis A Akkad, Stefan Wieczorek, Aiden Haghikia, Andrew Chan, Jörg T Epplen, Larissa Arning
Mol Neurodegener. 2011; 6: 32. Published online 2011 May 19. doi: 10.1186/1750-1326-6-32
PMCID:
PMC3117738
Abstract Full Text PDF–720K
Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter
Elodie Martin, Sandrine Betuing, Christiane Pagès, Karine Cambon, Gwenaelle Auregan, Nicole Deglon, Emmanuel Roze, Jocelyne Caboche
Hum Mol Genet. 2011 June 15; 20(12): 2422–2434. Published online 2011 April 14. doi: 10.1093/hmg/ddr148
PMCID:
PMC3098728
Abstract Full Text Supplementary Material
PGC-1 coactivators in the control of energy metabolism
Chang Liu, Jiandie D. Lin
Acta Biochim Biophys Sin (Shanghai) 2011 April; 43(4): 248–257. Published online 2011 February 16. doi: 10.1093/abbs/gmr007
PMCID:
PMC3063079
Abstract Full Text PDF–167K
Energy deficit in Huntington disease: why it matters
Fanny Mochel, Ronald G. Haller
J Clin Invest. 2011 February 1; 121(2): 493–499. Published online 2011 February 1. doi: 10.1172/JCI45691
PMCID:
PMC3026743
Abstract Full Text PDF–1.7M
Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease
Hong Van B Che, Silke Metzger, Esteban Portal, Carolin Deyle, Olaf Riess, Huu Phuc Nguyen
Mol Neurodegener. 2011; 6: 1. Published online 2011 January 6. doi: 10.1186/1750-1326-6-1
PMCID:
PMC3022537
Abstract Full Text PDF–279K
Meclizine is neuroprotective in models of Huntington's disease
Vishal M. Gohil, Nicolas Offner, James A. Walker, Sunil A. Sheth, Elisa Fossale, James F. Gusella, Marcy E. MacDonald, Christian Neri, Vamsi K. Mootha
Hum Mol Genet. 2011 January 15; 20(2): 294–300. Published online 2010 October 25. doi: 10.1093/hmg/ddq464
PMCID:
PMC3005902
Abstract Full Text PDF–257K
Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation
Rajnish K. Chaturvedi, Noel Y. Calingasan, Lichuan Yang, Thomas Hennessey, Ashu Johri, M. Flint Beal
Hum Mol Genet. 2010 August 15; 19(16): 3190–3205. Published online 2010 June 7. doi: 10.1093/hmg/ddq229
PMCID:
PMC2915615
Abstract Full Text PDF–821K
Minireview: The SRC Family of Coactivators: An Entrée to Understanding a Subset of Polygenic Diseases?
David M. Lonard, Rakesh Kumar, Bert W. O'Malley
Mol Endocrinol. 2010 February; 24(2): 279–285. Published online 2009 October 21. doi: 10.1210/me.2009-0276
PMCID:
PMC2817609
Abstract Full Text
Huntington's disease: the case for genetic modifiers
James F Gusella, Marcy E MacDonald
Genome Med. 2009; 1(8): 80. Published online 2009 August 21. doi: 10.1186/gm80
PMCID:
PMC2768966
Abstract Full Text PDF–317K
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