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The gene coding for PGC-1α modifies age at onset in Huntington's Disease
Patrick Weydt, Selma M Soyal, Cinzia Gellera, Stefano DiDonato, Claus Weidinger, Hannes Oberkofler, G Bernhard Landwehrmeyer, Wolfgang Patsch
Mol Neurodegener. 2009; 4: 3. Published online 2009 January 8. doi: 10.1186/1750-1326-4-3
PMCID:
PMC2630305
Abstract Full Text PDF–289K

Is Cited by the Following 14 Articles in this Archive:

Shaping the role of mitochondria in the pathogenesis of Huntington's disease
Veronica Costa, Luca Scorrano
EMBO J. 2012 April 18; 31(8): 1853–1864. Published online 2012 March 23. doi: 10.1038/emboj.2012.65
PMCID:
PMC3343341
Free in PMC on 2013/04/18
Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function
C. Ciron, S. Lengacher, J. Dusonchet, P. Aebischer, B.L. Schneider
Hum Mol Genet. 2012 April 15; 21(8): 1861–1876. Published online 2012 January 12. doi: 10.1093/hmg/ddr618
PMCID:
PMC3313800
Abstract Full Text PDF–671K
Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease
Ashu Johri, Noel Y. Calingasan, Thomas M. Hennessey, Abhijeet Sharma, Lichuan Yang, Elizabeth Wille, Abhishek Chandra, M. Flint Beal
Hum Mol Genet. 2012 March 1; 21(5): 1124–1137. Published online 2011 November 17. doi: 10.1093/hmg/ddr541
PMCID:
PMC3277311
Free in PMC on 2013/03/01
Characterization of Novel Peroxisome Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) Isoform in Human Liver
Thomas K. Felder, Selma M. Soyal, Hannes Oberkofler, Penelope Hahne, Simon Auer, Richard Weiss, Gabriele Gadermaier, Karl Miller, Franz Krempler, Harald Esterbauer, Wolfgang Patsch
J Biol Chem. 2011 December 16; 286(50): 42923–42936. Published online 2011 October 18. doi: 10.1074/jbc.M111.227496
PMCID:
PMC3234813
Free in PMC on 2012/12/16
NMDA receptor gene variations as modifiers in Huntington disease: a replication study
Carsten Saft, Jörg T. Epplen, Stefan Wieczorek, G. Bernhard Landwehrmeyer, Raymund A.C. Roos, Justo Garcia de Yebenes, Matthias Dose, Sarah J Tabrizi, David Craufurd, Investigators of the European Huntington's Disease Network, Larissa Arning
PLoS Curr. 2011 October 4; 3: RRN1247. doi: 10.1371/currents.RRN1247
PMCID:
PMC3186947
Abstract Full Text
PGC1α contributes to dysmyelination in experimental models of Huntington's disease
Zhongmin Xiang, Marta Valenza, Libin Cui, Valerio Leoni, Hyun-Kyung Jeong, Elisa Brilli, Jiangyang Zhang, Qi Peng, Wenzhen Duan, Steven A. Reeves, Elena Cattaneo, Dimitri Krainc
J Neurosci. Author manuscript; available in PMC 2011 December 29.
Published in final edited form as: J Neurosci. 2011 June 29; 31(26): 9544–9553. doi: 10.1523/JNEUROSCI.1291-11.2011
PMCID:
PMC3132810
Abstract Full Text PDF–1.9M
Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease
Joanne Clark, Sonika Reddy, Kangni Zheng, Rebecca A Betensky, David K Simon
BMC Med Genet. 2011; 12: 69. Published online 2011 May 19. doi: 10.1186/1471-2350-12-69
PMCID:
PMC3112073
Abstract Full Text PDF–214K Supplementary Material
PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease
Elahe Taherzadeh-Fard, Carsten Saft, Denis A Akkad, Stefan Wieczorek, Aiden Haghikia, Andrew Chan, Jörg T Epplen, Larissa Arning
Mol Neurodegener. 2011; 6: 32. Published online 2011 May 19. doi: 10.1186/1750-1326-6-32
PMCID:
PMC3117738
Abstract Full Text PDF–720K
The importance of integrating basic and clinical research toward the development of new therapies for Huntington disease
Ignacio Munoz-Sanjuan, Gillian P. Bates
J Clin Invest. 2011 February 1; 121(2): 476–483. Published online 2011 February 1. doi: 10.1172/JCI45364
PMCID:
PMC3026740
Abstract Full Text PDF–1.1M Supplementary Material
Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease
Hong Van B Che, Silke Metzger, Esteban Portal, Carolin Deyle, Olaf Riess, Huu Phuc Nguyen
Mol Neurodegener. 2011; 6: 1. Published online 2011 January 6. doi: 10.1186/1750-1326-6-1
PMCID:
PMC3022537
Abstract Full Text PDF–279K
Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation
Rajnish K. Chaturvedi, Noel Y. Calingasan, Lichuan Yang, Thomas Hennessey, Ashu Johri, M. Flint Beal
Hum Mol Genet. 2010 August 15; 19(16): 3190–3205. Published online 2010 June 7. doi: 10.1093/hmg/ddq229
PMCID:
PMC2915615
Abstract Full Text PDF–821K
Sumoylation Regulates Nuclear Localization of Lipin-1α in Neuronal Cells
Guang-Hui Liu, Larry Gerace
PLoS One. 2009; 4(9): e7031. Published online 2009 September 15. doi: 10.1371/journal.pone.0007031
PMCID:
PMC2737637
Abstract Full Text PDF–1.1M Supplementary Material
Huntington's disease: the case for genetic modifiers
James F Gusella, Marcy E MacDonald
Genome Med. 2009; 1(8): 80. Published online 2009 August 21. doi: 10.1186/gm80
PMCID:
PMC2768966
Abstract Full Text PDF–317K
PGC-1alpha as modifier of onset age in Huntington disease
Elahe Taherzadeh-Fard, Carsten Saft, Jürgen Andrich, Stefan Wieczorek, Larissa Arning
Mol Neurodegener. 2009; 4: 10. Published online 2009 February 6. doi: 10.1186/1750-1326-4-10
PMCID:
PMC2644307
Abstract Full Text PDF–242K
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