• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of iaiPermissionsJournals.ASM.orgJournalIAI ArticleJournal InfoAuthorsReviewers
Infect Immun. May 1985; 48(2): 507–519.
PMCID: PMC261360

Comparative bacteriology of juvenile periodontitis.


Statistical comparisons of the floras associated with juvenile periodontitis, severe periodontitis, and moderate periodontitis indicated that differences in the bacterial compositions of affected sites in these populations were not statistically significant. The subgingival flora of affected juvenile periodontitis sites was statistically significantly different from the adjacent supragingival flora and from the subgingival floras of people with healthy gingiva and of children with developing (experimental) gingivitis. However, the subgingival flora of affected juvenile periodontitis sites was not significantly different from the flora of sites with gingival index scores of 1 or 2 in adults with developing (experimental) gingivitis. Of 357 bacterial taxa among over 18,000 isolates, 54 non-treponemal species, 2 treponemal species, and mycoplasma were most associated with diseased periodontal sulci. These species comprised an increasing proportion of the flora during developing gingivitis and constituted over half of the cultivable flora of diseased sites.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.7M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Benjamin SD, Baer PN. Familial patterns of advanced alveolar bone loss in adolescence (periodontosis). Periodontics. 1967 Mar-Apr;5(2):82–88. [PubMed]
  • Burmeister JA, Best AM, Palcanis KG, Caine FA, Ranney RR. Localized juvenile periodontitis and generalized severe periodontitis: clinical findings. J Clin Periodontol. 1984 Mar;11(3):181–192. [PubMed]
  • Butler JH. A familial pattern of juvenile periodontitis (periodontosis). J Periodontol. 1969 Feb;40(2):115–118. [PubMed]
  • Ebersole JL, Taubman MA, Smith DJ, Genco RJ, Frey DE. Human immune responses to oral micro-organisms. I. Association of localized juvenile periodontitis (LJP) with serum antibody responses to Actinobacillus actinomycetemcomitans. Clin Exp Immunol. 1982 Jan;47(1):43–52. [PMC free article] [PubMed]
  • Jorgenson RJ, Levin LS, Hutcherson ST, Salinas CF. Periodontosis in sibs. Oral Surg Oral Med Oral Pathol. 1975 Mar;39(3):396–402. [PubMed]
  • Listgarten MA, Lai CH, Evian CI. Comparative antibody titers to Actinobacillus actinomycetemcomitans in juvenile periodontitis, chronic periodontitis and periodontally healthy subjects. J Clin Periodontol. 1981 Jun;8(3):155–164. [PubMed]
  • Mandell RL. A longitudinal microbiological investigation of Actinobacillus actinomycetemcomitans and Eikenella corrodens in juvenile periodontitis. Infect Immun. 1984 Sep;45(3):778–780. [PMC free article] [PubMed]
  • Mandell RL, Socransky SS. A selective medium for Actinobacillus actinomycetemcomitans and the incidence of the organism in juvenile periodontitis. J Periodontol. 1981 Oct;52(10):593–598. [PubMed]
  • Moore WE, Hash DE, Holdeman LV, Cato EP. Polyacrylamide slab gel electrophoresis of soluble proteins for studies of bacterial floras. Appl Environ Microbiol. 1980 Apr;39(4):900–907. [PMC free article] [PubMed]
  • Moore WE, Holdeman LV, Cato EP, Good IJ, Smith EP, Ranney RR, Palcanis KG. Variation in periodontal floras. Infect Immun. 1984 Dec;46(3):720–726. [PMC free article] [PubMed]
  • Moore WE, Holdeman LV, Cato EP, Smibert RM, Burmeister JA, Ranney RR. Bacteriology of moderate (chronic) periodontitis in mature adult humans. Infect Immun. 1983 Nov;42(2):510–515. [PMC free article] [PubMed]
  • Moore WE, Holdeman LV, Smibert RM, Cato EP, Burmeister JA, Palcanis KG, Ranney RR. Bacteriology of experimental gingivitis in children. Infect Immun. 1984 Oct;46(1):1–6. [PMC free article] [PubMed]
  • Moore WE, Holdeman LV, Smibert RM, Good IJ, Burmeister JA, Palcanis KG, Ranney RR. Bacteriology of experimental gingivitis in young adult humans. Infect Immun. 1982 Nov;38(2):651–667. [PMC free article] [PubMed]
  • Moore WE, Holdeman LV, Smibert RM, Hash DE, Burmeister JA, Ranney RR. Bacteriology of severe periodontitis in young adult humans. Infect Immun. 1982 Dec;38(3):1137–1148. [PMC free article] [PubMed]
  • Newman MG, Socransky SS. Predominant cultivable microbiota in periodontosis. J Periodontal Res. 1977 Mar;12(2):120–128. [PubMed]
  • Newman MG, Socransky SS, Savitt ED, Propas DA, Crawford A. Studies of the microbiology of periodontosis. J Periodontol. 1976 Jul;47(7):373–379. [PubMed]
  • Okuda K, Naito Y, Ohta K, Fukumoto Y, Kimura Y, Ishikawa I, Kinoshita S, Takazoe I. Bacteriological study of periodontal lesions in two sisters with juvenile periodontitis and their mother. Infect Immun. 1984 Jul;45(1):118–121. [PMC free article] [PubMed]
  • Ranney RR, Yanni NR, Burmeister JA, Tew JG. Relationship between attachment loss and precipitating serum antibody to Actinobacillus actinomycetemcomitans in adolescents and young adults having severe periodontal destruction. J Periodontol. 1982 Jan;53(1):1–7. [PubMed]
  • Savitt ED, Socransky SS. Distribution of certain subgingival microbial species in selected periodontal conditions. J Periodontal Res. 1984 Mar;19(2):111–123. [PubMed]
  • Saxén L. Heredity of juvenile periodontitis. J Clin Periodontol. 1980 Aug;7(4):276–288. [PubMed]
  • Slots J. The predominant cultivable organisms in juvenile periodontitis. Scand J Dent Res. 1976 Jan;84(1):1–10. [PubMed]
  • Slots J. Selective medium for isolation of Actinobacillus actinomycetemcomitans. J Clin Microbiol. 1982 Apr;15(4):606–609. [PMC free article] [PubMed]
  • Slots J, Reynolds HS, Genco RJ. Actinobacillus actinomycetemcomitans in human periodontal disease: a cross-sectional microbiological investigation. Infect Immun. 1980 Sep;29(3):1013–1020. [PMC free article] [PubMed]
  • Slots J, Rosling BG. Suppression of the periodontopathic microflora in localized juvenile periodontitis by systemic tetracycline. J Clin Periodontol. 1983 Sep;10(5):465–486. [PubMed]
  • Vandesteen GE, Williams BL, Ebersole JL, Altman LC, Page RC. Clinical, microbiological and immunological studies of a family with a high prevalence of early-onset periodontitis. J Periodontol. 1984 Mar;55(3):159–169. [PubMed]
  • Zambon JJ, Christersson LA, Slots J. Actinobacillus actinomycetemcomitans in human periodontal disease. Prevalence in patient groups and distribution of biotypes and serotypes within families. J Periodontol. 1983 Dec;54(12):707–711. [PubMed]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)


Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


  • MedGen
    Related information in MedGen
  • PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...