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J Natl Med Assoc. 1986 November; 78(11): 1073–1078.
PMCID: PMC2571420
Cholecystitis and Cholelithiasis in Children and Adolescents
Eulalia R.Y. Cheng and Matthias I. Okoye
Abstract
One hundred patients aged 20 years and younger, admitted to Hurley Medical Center during a ten-year period for treatment of acute or chronic cholecystitis with or without cholelithiasis, were reviewed. Results demonstrated an increasing incidence of pediatric cases compared with previous reports, a predominance in parous teenagers, and only an 8 percent association with hemolytic diseases. The clinical presentation is very similar to that of adults. Maintaining a high index of suspicion in addition to the use of diagnostic aids such as cholecystogram, ultrasonography, and hepatobiliary imaging with technetium 99m PIPIDA (paraisopropylacetanilide iminoacetate) should lead to the diagnosis of gallbladder disease even at a very early age. Elective cholecystectomy in the stable patient is the treatment of choice, and any delays in the diagnosis and treatment will increase morbidity and mortality considerably.
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Selected References
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  • Sears HF, Golden GT, Horsley JS., 3rd Cholecystitis in childhood and adolescence. Arch Surg. 1973 May;106(5):651–653. [PubMed]
  • Bennion LJ, Grundy SM. Risk factors for the development of cholelithiasis in man (second of two parts). N Engl J Med. 1978 Nov 30;299(22):1221–1227. [PubMed]
  • Goodman DB. Cholelithiasis in persons under 25 years old. Clinicopathologic review of 96 cases. JAMA. 1976 Oct 11;236(15):1731–1732. [PubMed]
  • Harned RK, Babbitt DP. Cholelithiasis in children. Radiology. 1975 Nov;117(2):391–393. [PubMed]
  • Strauss RG. Cholelithiasis in childhood. Am J Dis Child. 1969 Jun;117(6):689–692. [PubMed]
  • Tchirkow G, Highman LM, Shafer AD. Cholelithiasis and cholecystitis in children after repair of congenital duodenal anomalies. Arch Surg. 1980 Jan;115(1):85–86. [PubMed]
  • GLENN F, HILL MR., Jr Primary gallbladder disease in children. Ann Surg. 1954 Mar;139(3):302–311. [PubMed]
  • Holcomb GW, Jr, O'Neill JA, Jr, Holcomb GW., 3rd Cholecystitis, cholelithiasis and common duct stenosis in children and adolescents. Ann Surg. 1980 May;191(5):626–635. [PubMed]
  • Kirtley JA, Jr, Holcomb GW., Jr Surgical management of diseases of the gallbladder and common duct in children and adolescents. Am J Surg. 1966 Jan;111(1):39–46. [PubMed]
  • Sarnaik S, Slovis TL, Corbett DP, Emami A, Whitten CF. Incidence of cholelithiasis in sickle cell anemia using the ultrasonic gray-scale technique. J Pediatr. 1980 Jun;96(6):1005–1008. [PubMed]
  • Callahan J, Haller JO, Cacciarelli AA, Slovis TL, Friedman AP. Cholelithiasis in infants: association with total parenteral nutrition and furosemide. Radiology. 1982 May;143(2):437–439. [PubMed]
  • Callahan J, Haller JO, Cacciarelli AA, Slovis TL, Friedman AP. Cholelithiasis in infants: association with total parenteral nutrition and furosemide. Radiology. 1982 May;143(2):437–439. [PubMed]
  • Nehme AE, Mikhail RA. Kawasaki syndrome. An abdominal crisis. Am Surg. 1983 May;49(5):275–277. [PubMed]
  • Mukamel E, Zer M, Avidor I, Versano I, Rachmel A, Dintsman M. Acute acalculous cholecystitis in an infant: a case report. J Pediatr Surg. 1981 Aug;16(4):521–522. [PubMed]
  • Bloom RA, Swain VA. Non-calculous distension of the gall-bladder in childhood. Arch Dis Child. 1966 Oct;41(219):503–508. [PubMed]
  • Glenn F, Becker CG. Acute acalculous cholecystitis. An increasing entity. Ann Surg. 1982 Feb;195(2):131–136. [PubMed]
  • Karayalcin G, Hassani N, Abrams M, Lanzkowsky P. Cholelithiasis in children with sickle cell disease. Am J Dis Child. 1979 Mar;133(3):306–307. [PubMed]
  • Lachman BS, Lazerson J, Starshak RJ, Vaughters FM, Werlin SL. The prevalence of cholelithiasis in sickle cell disease as diagnosed by ultrasound and cholecystography. Pediatrics. 1979 Nov;64(5):601–603. [PubMed]
  • Detwiler RP, Kim DS, Longerbeam JK. Ultrasonography and oral cholecystography: a comparison of their use in the diagnosis of gallbladder disease. Arch Surg. 1980 Sep;115(9):1096–1098. [PubMed]
  • Handler SJ. Ultrasound of gallbladder wall thickening and its relation to cholecystitis. AJR Am J Roentgenol. 1979 Apr;132(4):581–585. [PubMed]
  • Bennett MT, Sheldon MI, dos Remedios LV, Weber PM. Diagnosis of acute cholecystitis using hepatobiliary scan with technetium-99m PIPIDA. Am J Surg. 1981 Sep;142(3):338–343. [PubMed]
  • Greenberg M, Kangarloo H, Cochran ST, Sample WF. The ultrasonographic diagnosis of cholecystitis and cholelithiasis in children. Radiology. 1980 Dec;137(3):745–749. [PubMed]
  • Howard RJ. Acute acalculous cholecystitis. Am J Surg. 1981 Feb;141(2):194–198. [PubMed]
  • Stephens CG, Scott RB. Cholelithiasis in sickle cell anemia: surgical or medical management. Arch Intern Med. 1980 May;140(5):648–651. [PubMed]