pmc logo image
Logo of jnmaJournal URL: http://www.nmanet.org/index.php/Publications_Sub/jnma

Formats:

J Natl Med Assoc. 1993 July; 85(7): 546–553.
PMCID: PMC2568155
The clinical and radiological evaluation of primary brain neoplasms in children, Part II: Radiological evaluation.
E. D. Allen, S. E. Byrd, C. F. Darling, T. Tomita, and M. A. Wilczynski
Department of Radiology, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois 60614.
Abstract
Data collected over the past 8 years on the radiological appearance of common pediatric primary brain neoplasms are presented. An emphasis is placed on the newer radiological imaging modality of magnetic resonance imaging (MRI). Part I of this article emphasized the clinical evaluation of these brain neoplasms. Three hundred eighty-five children with known brain neoplasms ranging in age from newborn to 18 years were evaluated with one or all of the following radiological modalities: MRI, computed tomography (CT), water-soluble myelography (WSM), WSM with CT, and angiography. Contrast-enhanced MRI and CT scans both were accurate in delineating these brain neoplasms although MRI provided better resolution and delineation than CT. Angiography provided information on the vascularity of the neoplasms and their relationship to prominent arterial and venous structures. Water-soluble myelography with CT and gadolinium-enhanced MRI of the spine were equally accurate in demonstrating metastatic spread to the spinal canal and spinal cord. Magnetic resonance imaging with gadolinium was more accurate than CT with contrast in demonstrating recurrent or residual neoplasm at the operative site and metastatic spread to the brain. Magnetic resonance imaging with gadolinium is the best radiological modality to fully evaluate pediatric brain neoplasms.
Full text
Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (3.7M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.
Images in this article
Click on the image to see a larger version.
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • Duffner PK, Cohen ME, Freeman AI. Pediatric brain tumors: an overview. CA Cancer J Clin. 1985 Sep–Oct;35(5):287–301. [PubMed]
  • Gusnard DA. Cerebellar neoplasms in children. Semin Roentgenol. 1990 Jul;25(3):263–278. [PubMed]
  • Farwell JR, Dohrmann GJ, Flannery JT. Central nervous system tumors in children. Cancer. 1977 Dec;40(6):3123–3132. [PubMed]
  • Sposto R, Ertel IJ, Jenkin RD, Boesel CP, Venes JL, Ortega JA, Evans AE, Wara W, Hammond D. The effectiveness of chemotherapy for treatment of high grade astrocytoma in children: results of a randomized trial. A report from the Childrens Cancer Study Group. J Neurooncol. 1989 Jul;7(2):165–177. [PubMed]
  • Palma L, Guidetti B. Cystic pilocytic astrocytomas of the cerebral hemispheres. Surgical experience with 51 cases and long-term results. J Neurosurg. 1985 Jun;62(6):811–815. [PubMed]
  • Berens ME, Rutka JT, Rosenblum ML. Brain tumor epidemiology, growth, and invasion. Neurosurg Clin N Am. 1990 Jan;1(1):1–18. [PubMed]
  • Vaquero J, Ramiro J, Martínez R, Coca S, Bravo G. Clinicopathological experience with pineocytomas: report of five surgically treated cases. Neurosurgery. 1990 Oct;27(4):612–619. [PubMed]
  • Edwards MS, Hudgins RJ, Wilson CB, Levin VA, Wara WM. Pineal region tumors in children. J Neurosurg. 1988 May;68(5):689–697. [PubMed]