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J Virol. May 1985; 54(2): 625–629.
PMCID: PMC254838

The pX region of the bovine leukemia virus is transcribed as a 2.1-kilobase mRNA.

Abstract

The bovine leukemia virus mRNAs expressed in cultured bovine cells of various origins are a 9.0-kilobase genomic RNA, a 5.1-kilobase env RNA, and a newly detected 2.1-kilobase RNA corresponding to the transcription of pX sequences located in between the env gene and the 3' end of the provirus.

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Selected References

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  • Chandler PM, Rimkus D, Davidson N. Gel electrophoretic fractionation of RNAs by partial denaturation with methylmercuric hydroxide. Anal Biochem. 1979 Oct 15;99(1):200–206. [PubMed]
  • Deschamps J, Kettmann R, Burny A. Experiments with cloned complete tumor-derived bovine leukemia virus information prove that the virus is totally exogenous to its target animal species. J Virol. 1981 Nov;40(2):605–609. [PMC free article] [PubMed]
  • Ghysdael J, Kettmann R, Burny A. Translation of bovine leukemia virus virion RNAs in heterologous protein-synthesizing systems. J Virol. 1979 Mar;29(3):1087–1098. [PMC free article] [PubMed]
  • Grégoire D, Couez D, Deschamps J, Heuertz S, Hors-Cayla MC, Szpirer J, Szpirer C, Burny A, Huez G, Kettmann R. Different bovine leukemia virus-induced tumors harbor the provirus in different chromosomes. J Virol. 1984 Apr;50(1):275–279. [PMC free article] [PubMed]
  • Haseltine WA, Sodroski J, Patarca R, Briggs D, Perkins D, Wong-Staal F. Structure of 3' terminal region of type II human T lymphotropic virus: evidence for new coding region. Science. 1984 Jul 27;225(4660):419–421. [PubMed]
  • Kawakami TG, Moore AL, Theilen GH, Munn RJ. Comparisons of virus-like particles from leukotic cattle to feline leukosis virus. Bibl Haematol. 1970;(36):471–475. [PubMed]
  • Kenyon SJ, Piper CE. Properties of density gradient-fractionated peripheral blood leukocytes from cattle infected with bovine leukemia virus. Infect Immun. 1977 Jun;16(3):898–903. [PMC free article] [PubMed]
  • Kettmann R, Couez D, Burny A. Restriction endonuclease mapping of linear unintegrated proviral DNA of bovine leukemia virus. J Virol. 1981 Apr;38(1):27–33. [PMC free article] [PubMed]
  • Kettmann R, Deschamps J, Cleuter Y, Couez D, Burny A, Marbaix G. Leukemogenesis by bovine leukemia virus: proviral DNA integration and lack of RNA expression of viral long terminal repeat and 3' proximate cellular sequences. Proc Natl Acad Sci U S A. 1982 Apr;79(8):2465–2469. [PMC free article] [PubMed]
  • Kettmann R, Deschamps J, Couez D, Claustriaux JJ, Palm R, Burny A. Chromosome integration domain for bovine leukemia provirus in tumors. J Virol. 1983 Jul;47(1):146–150. [PMC free article] [PubMed]
  • Kettmann R, Portetelle D, Mammerickx M, Cleuter Y, Dekegel D, Galoux M, Ghysdael J, Burny A, Chantrenne H. Bovine leukemia virus: an exogenous RNA oncogenic virus. Proc Natl Acad Sci U S A. 1976 Apr;73(4):1014–1018. [PMC free article] [PubMed]
  • Mamoun RZ, Astier T, Guillemain B. Establishment and propagation of a bovine leukaemia virus-producing cell line derived from the leukocyte of a leukaemic cow. J Gen Virol. 1981 Jun;54(Pt 2):357–365. [PubMed]
  • Mamoun RZ, Astier T, Guillemain B, Duplan JF. Bovine lymphosarcoma: expression of BLV-related proteins in cultured cells. J Gen Virol. 1983 Sep;64(Pt 9):1895–1905. [PubMed]
  • Mamoun RZ, Astier T, Guillemain B, Duplan JF. Bovine lymphosarcoma: processing of bovine leukaemia virus-coded proteins. J Gen Virol. 1983 Dec;64(Pt 12):2791–2795. [PubMed]
  • McMaster GK, Carmichael GG. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A. 1977 Nov;74(11):4835–4838. [PMC free article] [PubMed]
  • Miller JM, Miller LD, Olson C, Gillette KG. Virus-like particles in phytohemagglutinin-stimulated lymphocyte cultures with reference to bovine lymphosarcoma. J Natl Cancer Inst. 1969 Dec;43(6):1297–1305. [PubMed]
  • Neel BG, Hayward WS, Robinson HL, Fang J, Astrin SM. Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: oncogenesis by promoter insertion. Cell. 1981 Feb;23(2):323–334. [PubMed]
  • Paul PS, Pomeroy KA, Castro AE, Johnson DW, Muscoplat CC, Sorensen DK. Detection of bovine leukemia virus in B-lymphocytes by the syncytia induction assay. J Natl Cancer Inst. 1977 Oct;59(4):1269–1272. [PubMed]
  • Rice NR, Stephens RM, Couez D, Deschamps J, Kettmann R, Burny A, Gilden RV. The nucleotide sequence of the env gene and post-env region of bovine leukemia virus. Virology. 1984 Oct 15;138(1):82–93. [PubMed]
  • Seiki M, Hattori S, Hirayama Y, Yoshida M. Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA. Proc Natl Acad Sci U S A. 1983 Jun;80(12):3618–3622. [PMC free article] [PubMed]
  • Stock ND, Ferrer JF. Replicating C-type virus in phytohemagglutinin-treated buffy-coat cultures of bovine origin. J Natl Cancer Inst. 1972 Apr;48(4):985–996. [PubMed]

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