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Natural variation of HIV-1 group M integrase: Implications for a new class of antiretroviral inhibitors
Soo-Yon Rhee, Tommy F Liu, Mark Kiuchi, Rafael Zioni, Robert J Gifford, Susan P Holmes, Robert W Shafer
Retrovirology. 2008; 5: 74. Published online 2008 August 7. doi: 10.1186/1742-4690-5-74
PMCID:
PMC2546438
Abstract Full Text PDF–375K Supplementary Material
 Is Cited by the Following 19 Articles in this Archive:
HIV-1 Integrase Inhibitor Resistance and Its Clinical Implications
Jose-Luis Blanco, Vici Varghese, Soo-Yon Rhee, Jose M. Gatell, Robert W. Shafer
J Infect Dis. 2011 May 1; 203(9): 1204–1214. doi: 10.1093/infdis/jir025
PMCID:
PMC3069732
Abstract Full Text PDF–219K
HIV integrase variability and genetic barrier in antiretroviral naïve and experienced patients
Antonio Piralla, Stefania Paolucci, Roberto Gulminetti, Giuditta Comolli, Fausto Baldanti
Virol J. 2011; 8: 149. Published online 2011 March 31. doi: 10.1186/1743-422X-8-149
PMCID:
PMC3077329
Abstract Full Text PDF–214K
Patterns of resistance development with integrase inhibitors in HIV
Jean L Mbisa, Supang A Martin, Patricia A Cane
Infect Drug Resist. 2011; 4: 65–76. Published online 2011 February 22. doi: 10.2147/IDR.S7775
PMCID:
PMC3108751
Abstract Full Text PDF–1.3M
Transmitted resistance to HIV integrase strand-transfer inhibitors: right on schedule
Christopher B. Hurt
Antivir Ther. Author manuscript; available in PMC 2012 January 1.
Published in final edited form as: Antivir Ther. 2011; 16(2): 137–140. doi: 10.3851/IMP1750
PMCID:
PMC3139474
Abstract Full Text PDF–34K
Transmitted raltegravir resistance in an HIV-1 CRF_AG-infected patient
Sarita D. Boyd, Frank Maldarelli, Irini Sereti, G. Laissa Ouedraogo, Catherine A. Rehm, Valerie Boltz, Diana Shoemaker, Alice K. Pau
Antivir Ther. Author manuscript; available in PMC 2011 August 4.
Published in final edited form as: Antivir Ther. 2011; 16(2): 257–261. doi: 10.3851/IMP1749
PMCID:
PMC3150494
Abstract Full Text PDF–55K
The HIV-1 Integrase α4-Helix Involved in LTR-DNA Recognition Is also a Highly Antigenic Peptide Element
Sandy Azzi, Vincent Parissi, Richard G. Maroun, Pierre Eid, Olivier Mauffret, Serge Fermandjian
PLoS One. 2010; 5(12): e16001. Published online 2010 December 30. doi: 10.1371/journal.pone.0016001
PMCID:
PMC3012736
Abstract Full Text PDF–446K
Analysis of Low-Frequency Mutations Associated with Drug Resistance to Raltegravir before Antiretroviral Treatment
Jia Liu, Michael D. Miller, Robert M. Danovich, Nathan Vandergrift, Fangping Cai, Charles B. Hicks, Daria J. Hazuda, Feng Gao
Antimicrob Agents Chemother. 2011 March; 55(3): 1114–1119. Published online 2010 December 20. doi: 10.1128/AAC.01492-10
PMCID:
PMC3067114
Abstract Full Text PDF–496K
HIV-1 Integrase Sequence Variability in Antiretroviral Naïve Patients and in Triple-Class Experienced Patients Subsequently Treated with Raltegravir
Vici Varghese, Tommy F. Liu, Soo-Yon Rhee, Paolo Libiran, Christina Trevino, W. Jeffrey Fessel, Robert W. Shafer
AIDS Res Hum Retroviruses. 2010 December; 26(12): 1323–1326. doi: 10.1089/aid.2010.0123
PMCID:
PMC2996813
Abstract Full Text PDF–123K Supplementary Material
Polymorphisms of HIV-2 integrase and selection of resistance to raltegravir
Danielle Perez Bercoff, Perrine Triqueneaux, Christine Lambert, Aboubacar Alassane Oumar, Anne-Marie Ternes, Sounkalo Dao, Patrick Goubau, Jean-Claude Schmit, Jean Ruelle
Retrovirology. 2010; 7: 98. Published online 2010 November 29. doi: 10.1186/1742-4690-7-98
PMCID:
PMC3006360
Abstract Full Text PDF–479K Supplementary Material
Subtype-associated differences in HIV-1 reverse transcription affect the viral replication
Sergey Iordanskiy, Mackenzie Waltke, Yanjun Feng, Charles Wood
Retrovirology. 2010; 7: 85. Published online 2010 October 12. doi: 10.1186/1742-4690-7-85
PMCID:
PMC2964588
Abstract Full Text PDF–2.1M
Identification of Novel Mutations Responsible for Resistance to MK-2048, a Second-Generation HIV-1 Integrase Inhibitor
Tamara Bar-Magen, Richard D. Sloan, Daniel A. Donahue, Björn D. Kuhl, Alexandra Zabeida, Hongtao Xu, Maureen Oliveira, Daria J. Hazuda, Mark A. Wainberg
J Virol. 2010 September; 84(18): 9210–9216. Published online 2010 July 7. doi: 10.1128/JVI.01164-10
PMCID:
PMC2937597
Abstract Full Text PDF–791K
Secondary Integrase Resistance Mutations Found in HIV-1 Minority Quasispecies in Integrase Therapy-Naive Patients Have Little or No Effect on Susceptibility to Integrase Inhibitors
Francesca Ceccherini-Silberstein, Kurt Van Baelen, Daniele Armenia, Maria Trignetti, Evelien Rondelez, Lavinia Fabeni, Fernanda Scopelliti, Michela Pollicita, Liesbeth Van Wesenbeeck, Veerle Van Eygen, Luca Dori, Loredana Sarmati, Stefano Aquaro, Guido Palamara, Massimo Andreoni, Lieven J. Stuyver, Carlo Federico Perno
Antimicrob Agents Chemother. 2010 September; 54(9): 3938–3948. Published online 2010 May 17. doi: 10.1128/AAC.01720-09
PMCID:
PMC2935022
Abstract Full Text PDF–923K
Specificity of LTR DNA recognition by a peptide mimicking the HIV-1 integrase α4 helix
Zeina Hobaika, Loussine Zargarian, Yves Boulard, Richard G. Maroun, Olivier Mauffret, Serge Fermandjian
Nucleic Acids Res. 2009 December; 37(22): 7691–7700. Published online 2009 December. doi: 10.1093/nar/gkp824
PMCID:
PMC2794180
Abstract Full Text PDF–3.5M Supplementary Material
Panel of Prototypical Raltegravir-Resistant Infectious Molecular Clones in a Novel Integrase-Deleted Cloning Vector
Elizabeth C. Reuman, Michael H. Bachmann, Vici Varghese, W. Jeffrey Fessel, Robert W. Shafer
Antimicrob Agents Chemother. 2010 February; 54(2): 934–936. Published online 2009 November 16. doi: 10.1128/AAC.01345-09
PMCID:
PMC2812164
Abstract Full Text PDF–95K
Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase
Mohd J Dar, Blandine Monel, Lavanya Krishnan, Ming-Chieh Shun, Francesca Di Nunzio, Dag E Helland, Alan Engelman
Retrovirology. 2009; 6: 94. Published online 2009 October 19. doi: 10.1186/1742-4690-6-94
PMCID:
PMC2770994
Abstract Full Text PDF–912K
Loss of Raltegravir Susceptibility by Human Immunodeficiency Virus Type 1 Is Conferred via Multiple Nonoverlapping Genetic Pathways
Signe Fransen, Soumi Gupta, Robert Danovich, Daria Hazuda, Michael Miller, Marc Witmer, Christos J. Petropoulos, Wei Huang
J Virol. 2009 November; 83(22): 11440–11446. Published online 2009 September 16. doi: 10.1128/JVI.01168-09
PMCID:
PMC2772690
Abstract Full Text PDF–259K
Piecing together the structure of retroviral integrase, an important target in AIDS therapy
Mariusz Jaskolski, Jerry N. Alexandratos, Grzegorz Bujacz, Alexander Wlodawer
FEBS J. Author manuscript; available in PMC 2010 June 1.
Published in final edited form as: FEBS J. 2009 June; 276(11): 2926–2946. Published online 2009 April 14. doi: 10.1111/j.1742-4658.2009.07009.x
PMCID:
PMC2747025
Abstract Full Text PDF–1.8M Supplementary Material
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors
Erik Serrao, Srinivas Odde, Kavya Ramkumar, Nouri Neamati
Retrovirology. 2009; 6: 25. Published online 2009 March 5. doi: 10.1186/1742-4690-6-25
Correction in:
Retrovirology. 2009; 6: 33.
PMCID:
PMC2660292
Abstract Full Text PDF–981K Supplementary Material Correction
HIV-1 integrase polymorphisms are associated with prior antiretroviral drug exposure
Sebastiaan J van Hal, Belinda Herring, Zaquan Deris, Bin Wang, Nitin K Saksena, Dominic E Dwyer
Retrovirology. 2009; 6: 12. Published online 2009 February 9. doi: 10.1186/1742-4690-6-12
PMCID:
PMC2649883
Abstract Full Text PDF–185K
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