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BMJ. Aug 6, 1994; 309(6951): 369–372.
PMCID: PMC2541246

Deaths, HIV infection, abstinence, and other outcomes in a cohort of injecting drug users followed up for 10 years.

Abstract

OBJECTIVE--To trace, follow up, and interview a group of patients known to be injecting drug users in order to establish current drug taking and other features related to drug use over 10 years. DESIGN--Descriptive follow up study of a cohort of injecting drug users established between 1982 and 1985. SETTING--General practice based patient population study initially, with later tracing of subjects throughout the United Kingdom through NHS Central Registries and current general practitioners. SUBJECTS--203 injecting drug users recruited up to December 1985. MAIN OUTCOME MEASURES--Survival, cause of death, abstinence, or continued drug use; HIV status; and demographic variables. RESULTS--Of the 203 injecting drug users recruited into the study, over half were known to be HIV positive and 42 died of various causes (increasingly AIDS). From the start of follow up in 1990, 163 (91%) of the 180 survivors were traced, of whom 116 (71%) were interviewed. Dramatic changes had occurred in drug taking, with a move away from injecting towards oral drug use. A few patients, however, continued to inject. 90 (78%) of those interviewed had been in prison, of whom 37 (41%) had injected drugs while in prison. CONCLUSIONS--The pattern of deaths had changed from being largely due to overdose in the early 1980s to predominantly AIDS related in later years. The reduction in deaths due to overdose may have been connected with but was not always causally related to a new approach by legal, social, and medical services. Drug use continues in a modified form in a large proportion of patients followed up. As a group, drug users require long term support for a multiplicity of problems.

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Selected References

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  • Bewley TH, Ben-Arie O, James IP. Morbidity and mortality from heroin dependence. 1. Survey of heroin addicts known to home office. Br Med J. 1968 Mar 23;1(5594):725–726. [PMC free article] [PubMed]
  • Bucknall AB, Robertson JR. Deaths of heroin users in a general practice population. J R Coll Gen Pract. 1986 Mar;36(284):120–122. [PMC free article] [PubMed]
  • Robins LN. The sixth Thomas James Okey Memorial Lecture. Vietnam veterans' rapid recovery from heroin addiction: a fluke or normal expectation? Addiction. 1993 Aug;88(8):1041–1054. [PubMed]
  • Skidmore CA, Robertson JR, Robertson AA, Elton RA. After the epidemic: follow up study of HIV seroprevalence and changing patterns of drug use. BMJ. 1990 Jan 27;300(6719):219–223. [PMC free article] [PubMed]
  • Robertson JR, Skidmore CA, Roberts JJ. HIV infection in intravenous drug users: a follow-up study indicating changes in risk-taking behaviour. Br J Addict. 1988 Apr;83(4):387–391. [PubMed]
  • Skidmore CA, Robertson JR, Roberts JJ. Changes in HIV risk-taking behaviour in intravenous drug users: a second follow-up. Br J Addict. 1989 Jun;84(6):695–696. [PubMed]
  • Dunne FJ. Subcortical dementia. BMJ. 1993 Jul 3;307(6895):1–2. [PMC free article] [PubMed]
  • Greenwood J. Creating a new drug service in Edinburgh. BMJ. 1990 Mar 3;300(6724):587–589. [PMC free article] [PubMed]
  • Dementia--the quiet epidemic. Br Med J. 1978 Jan 7;1(6104):1–2. [PMC free article] [PubMed]
  • Vaillant GE. A 20-year follow-up of New York narcotic addicts. Arch Gen Psychiatry. 1973 Aug;29(2):237–241. [PubMed]
  • Chapple PA, Somekh DE, Taylor ME. A five-year follow-up of 108 cases of opiate addiction. I. General findings and a suggested method of staging. Br J Addict Alcohol Other Drugs. 1972 Mar;67(1):33–38. [PubMed]
  • Bath GE, Davies AG, Dominy NJ, Peters A, Raab G, Richardson AM. Imprisonment and HIV prevalence. Lancet. 1993 Nov 27;342(8883):1368–1368. [PubMed]
  • Cherubin CE, Sapira JD. The medical complications of drug addiction and the medical assessment of the intravenous drug user: 25 years later. Ann Intern Med. 1993 Nov 15;119(10):1017–1028. [PubMed]
  • Selwyn PA. Illicit drug use revisited: what a long, strange trip it's been. Ann Intern Med. 1993 Nov 15;119(10):1044–1046. [PubMed]

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