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Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role
Luca Giliberto, Dawang Zhou, Richard Weldon, Elena Tamagno, Pasquale De Luca, Massimo Tabaton, Luciano D'Adamio
Mol Neurodegener. 2008; 3: 12. Published online 2008 September 2. doi: 10.1186/1750-1326-3-12
PMCID:
PMC2538519
Abstract Full Text PDF–785K

Is Cited by the Following 22 Articles in this Archive:

Physiological Functions of APP Family Proteins
Ulrike C. Müller, Hui Zheng
Cold Spring Harb Perspect Med. 2012 February; 2(2): a006288. doi: 10.1101/cshperspect.a006288
PMCID:
PMC3281588
Abstract Full Text PDF–733K
Biochemical Inhibition of the Acetyltransferases ATase1 and ATase2 Reduces β-Secretase (BACE1) Levels and Aβ Generation
Yun Ding, Mi Hee Ko, Mariana Pehar, Frank Kotch, Noel R. Peters, Yun Luo, Shahriar M. Salamat, Luigi Puglielli
J Biol Chem. 2012 March 9; 287(11): 8424–8433. Published online 2012 January 20. doi: 10.1074/jbc.M111.310136
PMCID:
PMC3318698
Abstract Full Text Supplementary Material
Proteolytic processing of Alzheimer’s β-amyloid precursor protein
Han Zhang, Qilin Ma, Yun-wu Zhang, Huaxi Xu
J Neurochem. Author manuscript; available in PMC 2013 January 1.
Published in final edited form as: J Neurochem. 2012 January; 120(Suppl 1): 9–21. Published online 2011 November 28. doi: 10.1111/j.1471-4159.2011.07519.x
PMCID:
PMC3254787
Free in PMC on 2013/01/01
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling APP regulates TrkA
C Matrone, APM Barbagallo, LR La Rosa, F Florenzano, MT Ciotti, D Mercanti, MV Chao, P Calissano, L D’Adamio
J Neurosci. Author manuscript; available in PMC 2012 April 4.
Published in final edited form as: J Neurosci. 2011 August 17; 31(33): 11756–11761. doi: 10.1523/JNEUROSCI.1960-11.2011
PMCID:
PMC3319322
Abstract Full Text PDF–1.5M
APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant
Robert Tamayev, Shuji Matsuda, Luca Giliberto, Ottavio Arancio, Luciano D'Adamio
EMBO J. 2011 June 15; 30(12): 2501–2509. Published online 2011 May 17. doi: 10.1038/emboj.2011.161
PMCID:
PMC3116289
Free in PMC on 2012/06/15
Biology and pathophysiology of the amyloid precursor protein
Hui Zheng, Edward H Koo
Mol Neurodegener. 2011; 6: 27. Published online 2011 April 28. doi: 10.1186/1750-1326-6-27
PMCID:
PMC3098799
Abstract Full Text PDF–1.8M
Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex
Dorothee Aydin, Mikhail A Filippov, Jakob-Andreas Tschäpe, Norbert Gretz, Marco Prinz, Roland Eils, Benedikt Brors, Ulrike C Müller
BMC Genomics. 2011; 12: 160. Published online 2011 March 24. doi: 10.1186/1471-2164-12-160
PMCID:
PMC3080314
Abstract Full Text PDF–817K Supplementary Material
A Single Tyrosine Residue in the Amyloid Precursor Protein Intracellular Domain Is Essential for Developmental Function
Alessia P. M. Barbagallo, Zilai Wang, Hui Zheng, Luciano D'Adamio
J Biol Chem. 2011 March 18; 286(11): 8717–8721. Published online 2011 January 25. doi: 10.1074/jbc.C111.219873
PMCID:
PMC3059018
Abstract Full Text
APP processing in Alzheimer's disease
Yun-wu Zhang, Robert Thompson, Han Zhang, Huaxi Xu
Mol Brain. 2011; 4: 3. Published online 2011 January 7. doi: 10.1186/1756-6606-4-3
PMCID:
PMC3022812
Abstract Full Text PDF–561K
Tyr682 in the Intracellular Domain of APP Regulates Amyloidogenic APP Processing In Vivo
Alessia P. M. Barbagallo, Richard Weldon, Robert Tamayev, Dawang Zhou, Luca Giliberto, Oded Foreman, Luciano D'Adamio
PLoS One. 2010; 5(11): e15503. Published online 2010 November 16. doi: 10.1371/journal.pone.0015503
PMCID:
PMC2982846
Abstract Full Text PDF–746K
Characterization and use of human brain microvascular endothelial cells to examine β-amyloid exchange in the blood-brain barrier
Corbin Bachmeier, Michael Mullan, Daniel Paris
Cytotechnology. 2010 December; 62(6): 519–529. Published online 2010 October 19. doi: 10.1007/s10616-010-9313-x
PMCID:
PMC2995137
Abstract Full Text PDF–382K
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
Hongmei Li, Baiping Wang, Zilai Wang, Qinxi Guo, Katsuhiko Tabuchi, Robert E. Hammer, Thomas C. Südhof, Hui Zheng
Proc Natl Acad Sci U S A. 2010 October 5; 107(40): 17362–17367. Published online 2010 September 20. doi: 10.1073/pnas.1012568107
PMCID:
PMC2951422
Abstract Full Text PDF–1022K Supplementary Material
Transgenic Expression of the Amyloid-β Precursor Protein-Intracellular Domain Does Not Induce Alzheimer's Disease–Like Traits In Vivo
Luca Giliberto, Cristina d'Abramo, Christopher Michael Acker, Peter Davies, Luciano D'Adamio
PLoS One. 2010; 5(7): e11609. Published online 2010 July 16. doi: 10.1371/journal.pone.0011609
PMCID:
PMC2905372
Abstract Full Text PDF–1.0M
Aging and excitotoxic stress exacerbate neural circuit reorganization in APP intracellular domain (AICD) transgenic mice
Kaushik Ghosal, Sanjay W. Pimplikar
Neurobiol Aging. Author manuscript; available in PMC 2012 December 1.
Published in final edited form as: Neurobiol Aging. 2011 December; 32(12): 2320.e1–2320.e9. Published online 2010 May 20. doi: 10.1016/j.neurobiolaging.2010.04.020
PMCID:
PMC2928862
Free in PMC on 2012/12/01
Generation and Initial Characterization of FDD Knock In Mice
Luca Giliberto, Shuji Matsuda, Ruben Vidal, Luciano D'Adamio
PLoS One. 2009; 4(11): e7900. Published online 2009 November 18. doi: 10.1371/journal.pone.0007900
PMCID:
PMC2774945
Abstract Full Text PDF–3.7M
CD74 interacts with APP and suppresses the production of Aβ
Shuji Matsuda, Yukiko Matsuda, Luciano D'Adamio
Mol Neurodegener. 2009; 4: 41. Published online 2009 October 22. doi: 10.1186/1750-1326-4-41
PMCID:
PMC2770512
Abstract Full Text PDF–1.8M
Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain
Vogt DL, Thomas D, Galvan V, Bredesen DE, Lamb BT, Pimplikar SW
Neurobiol Aging. Author manuscript; available in PMC 2012 September 1.
Published in final edited form as: Neurobiol Aging. 2011 September; 32(9): 1725–1729. Published online 2009 October 13. doi: 10.1016/j.neurobiolaging.2009.09.002
PMCID:
PMC2889215
Free in PMC on 2012/09/01
The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains
Robert Tamayev, Dawang Zhou, Luciano D'Adamio
Mol Neurodegener. 2009; 4: 28. Published online 2009 July 14. doi: 10.1186/1750-1326-4-28
PMCID:
PMC2723102
Abstract Full Text PDF–1.2M
Neurodegeneration in Alzheimer's disease: caspases and synaptic element interdependence
Dale E Bredesen
Mol Neurodegener. 2009; 4: 27. Published online 2009 June 26. doi: 10.1186/1750-1326-4-27
PMCID:
PMC2709109
Abstract Full Text PDF–1020K
BRI3 Inhibits Amyloid Precursor Protein Processing in a Mechanistically Distinct Manner from Its Homologue Dementia Gene BRI2
Shuji Matsuda, Yukiko Matsuda, Luciano D'Adamio
J Biol Chem. 2009 June 5; 284(23): 15815–15825. Published online 2009 April 14. doi: 10.1074/jbc.M109.006403
PMCID:
PMC2708878
Abstract Full Text
Mutant Presenilin 1 Increases the Expression and Activity of BACE1
Luca Giliberto, Roberta Borghi, Alessandra Piccini, Rosa Mangerini, Sandro Sorbi, Gabriella Cirmena, Anna Garuti, Bernardino Ghetti, Fabrizio Tagliavini, Mohamed R. Mughal, Mark P. Mattson, Xiongwei Zhu, Xinglong Wang, Michela Guglielmotto, Elena Tamagno, Massimo Tabaton
J Biol Chem. 2009 April 3; 284(14): 9027–9038. doi: 10.1074/jbc.M805685200
PMCID:
PMC2666551
Abstract Full Text Supplementary Material
The Multi-Copy Mouse Gene Sycp3-Like Y-Linked (Sly) Encodes an Abundant Spermatid Protein That Interacts with a Histone Acetyltransferase and an Acrosomal Protein
Louise N. Reynard, Julie Cocquet, Paul S. Burgoyne
Biol Reprod. 2009 August; 81(2): 250–257. Published online 2009 January 28. doi: 10.1095/biolreprod.108.075382
PMCID:
PMC2849823
Abstract Full Text PDF–3.4M Supplementary Material
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