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J Natl Med Assoc. 1977 September; 69(9): 655–658.
PMCID: PMC2536943
Vagotomy for Relief of Pain in Some Upper Gastrointestinal Neoplasms
Oluwole G. Ajao
Abstract
At the University College Hospital, Ibadan, Nigeria, upper gastrointestinal neoplasms are usually seen very late when they have become unresectable. The resectable upper gastrointestinal neoplasms seen in this institution are less than ten percent of all the cases seen. The reasons for such delay before presentation are ignorance and fear of hospitals.
Following an editorial by Merendino,1 a study was conducted on ten patients who had inoperable upper gastrointestinal neoplasms. Even though the assessment of pain sensation has many variables, and there is a significant suggestive effect in any pain-relieving procedure, it is felt that vagotomy combined with any indicated diversion procedures definitely reduces the pain associated with terminal upper gastrointestinal neoplasms, while not affecting patient mortality.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • MERENDINO KA. VAGOTOMY FOR THE RELIEF OF PAIN SECONDARY TO PANCREATIC CARCINOMA. Am J Surg. 1964 Jul;108:1–2. [PubMed]
  • STAVNEY LS, KATO T, GRIFFITH CA, NYHUS LM, HARKINS HN. A PHYSIOLOGIC STUDY OF MOTILITY CHANGES FOLLOWING SELECTIVE GASTRIC VAGOTOMY. J Surg Res. 1963 Oct;3:390–394. [PubMed]
  • Pritchard GR, Griffith CA, Harkins HN. A physiologic demonstration of the anatomic distribution of the vagal system to the stomach. Surg Gynecol Obstet. 1968 Apr;126(4):791–798. [PubMed]
  • JOHNSON FE, BOYDEN EA. The effect of double vagotomy on the motor activity of the human gall bladder. Surgery. 1952 Sep;32(3):591–601. [PubMed]
  • Melzack R, Torgerson WS. On the language of pain. Anesthesiology. 1971 Jan;34(1):50–59. [PubMed]
  • Chapman CR. Letter: some pitfalls in the psychophysical assessment of drug effects: another look at the effects of diazepam on pain threshold. Br J Anaesth. 1975 May;47(5):640–642. [PubMed]
  • Rodbard S. Pain associated with muscular activity. Am Heart J. 1975 Jul;90(1):84–92. [PubMed]