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Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy
Jean-Michel Ubeda, Danielle Légaré, Frédéric Raymond, Amin Ahmed Ouameur, Sébastien Boisvert, Philippe Rigault, Jacques Corbeil, Michel J Tremblay, Martin Olivier, Barbara Papadopoulou, Marc Ouellette
Genome Biol. 2008; 9(7): R115. Published online 2008 July 18. doi: 10.1186/gb-2008-9-7-r115
PMCID:
PMC2530873
Abstract Full Text PDF–1.0M Supplementary Material
 Is Cited by the Following 11 Articles in this Archive:
Impact of Continuous Axenic Cultivation in Leishmania infantum Virulence
Diana Moreira, Nuno Santarém, Inês Loureiro, Joana Tavares, Ana Marta Silva, Ana Marina Amorim, Ali Ouaissi, Anabela Cordeiro-da-Silva, Ricardo Silvestre
PLoS Negl Trop Dis. 2012 January; 6(1): e1469. Published online 2012 January 24. doi: 10.1371/journal.pntd.0001469
PMCID:
PMC3265455
Abstract Full Text PDF–663K Supplementary Material
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania
Matthew B. Rogers, James D. Hilley, Nicholas J. Dickens, Jon Wilkes, Paul A. Bates, Daniel P. Depledge, David Harris, Yerim Her, Pawel Herzyk, Hideo Imamura, Thomas D. Otto, Mandy Sanders, Kathy Seeger, Jean-Claude Dujardin, Matthew Berriman, Deborah F. Smith, Christiane Hertz-Fowler, Jeremy C. Mottram
Genome Res. 2011 December; 21(12): 2129–2142. doi: 10.1101/gr.122945.111
PMCID:
PMC3227102
Abstract Full Text PDF–1.3M
Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance
Tim Downing, Hideo Imamura, Saskia Decuypere, Taane G. Clark, Graham H. Coombs, James A. Cotton, James D. Hilley, Simonne de Doncker, Ilse Maes, Jeremy C. Mottram, Mike A. Quail, Suman Rijal, Mandy Sanders, Gabriele Schönian, Olivia Stark, Shyam Sundar, Manu Vanaerschot, Christiane Hertz-Fowler, Jean-Claude Dujardin, Matthew Berriman
Genome Res. 2011 December; 21(12): 2143–2156. doi: 10.1101/gr.123430.111
PMCID:
PMC3227103
Abstract Full Text PDF–633K
Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species
Frédéric Raymond, Sébastien Boisvert, Gaétan Roy, Jean-François Ritt, Danielle Légaré, Amandine Isnard, Mario Stanke, Martin Olivier, Michel J. Tremblay, Barbara Papadopoulou, Marc Ouellette, Jacques Corbeil
Nucleic Acids Res. 2012 February; 40(3): 1131–1147. Published online 2011 October 13. doi: 10.1093/nar/gkr834
PMCID:
PMC3273817
Abstract Full Text PDF–11M Supplementary Material
Intrachromosomal tandem duplication and repeat expansion during attempts to inactivate the subtelomeric essential gene GSH1 in Leishmania
Angana Mukherjee, Lance D. Langston, Marc Ouellette
Nucleic Acids Res. 2011 September; 39(17): 7499–7511. Published online 2011 June 21. doi: 10.1093/nar/gkr494
PMCID:
PMC3177219
Abstract Full Text PDF–15M Supplementary Material
Gene Expression Profiling and Molecular Characterization of Antimony Resistance in Leishmania amazonensis
Rubens L. do Monte-Neto, Adriano C. Coelho, Frédéric Raymond, Danielle Légaré, Jacques Corbeil, Maria N. Melo, Frédéric Frézard, Marc Ouellette
PLoS Negl Trop Dis. 2011 May; 5(5): e1167. Published online 2011 May 24. doi: 10.1371/journal.pntd.0001167
PMCID:
PMC3101167
Abstract Full Text PDF–645K Supplementary Material
Functional Genome Annotation by Combined Analysis across Microarray Studies of Trypanosoma brucei
Hamed Shateri Najafabadi, Reza Salavati
PLoS Negl Trop Dis. 2010 August; 4(8): e810. Published online 2010 August 31. doi: 10.1371/journal.pntd.0000810
PMCID:
PMC2930875
Abstract Full Text PDF–676K Supplementary Material
Regulation of CD8+ T Cell Responses to Infection With Parasitic Protozoa
Kimberly A. Jordan, Christopher A. Hunter
Exp Parasitol. Author manuscript; available in PMC 2011 November 1.
Published in final edited form as: Exp Parasitol. 2010 November; 126(3): 318–325. Published online 2010 May 21. doi: 10.1016/j.exppara.2010.05.008
PMCID:
PMC2934887
Full Text PDF–85K
High Affinity S-Adenosylmethionine Plasma Membrane Transporter of Leishmania Is a Member of the Folate Biopterin Transporter (FBT) Family
Larbi Dridi, Amin Ahmed Ouameur, Marc Ouellette
J Biol Chem. 2010 June 25; 285(26): 19767–19775. Published online 2010 April 20. doi: 10.1074/jbc.M110.114520
PMCID:
PMC2888387
Abstract Full Text Supplementary Material
Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum
Philippe Leprohon, Danielle Légaré, Frédéric Raymond, Éric Madore, Gary Hardiman, Jacques Corbeil, Marc Ouellette
Nucleic Acids Res. 2009 April; 37(5): 1387–1399. Published online 2009 April. doi: 10.1093/nar/gkn1069
PMCID:
PMC2655676
Abstract Full Text PDF–7.7M
Formation of new chromosomes as a virulence mechanism in yeast Candida glabrata
Silvia Poláková, Christian Blume, Julián Álvarez Zárate, Marek Mentel, Dorte Jørck-Ramberg, Jørgen Stenderup, Jure Piškur
Proc Natl Acad Sci U S A. 2009 February 24; 106(8): 2688–2693. Published online 2009 February 9. doi: 10.1073/pnas.0809793106
PMCID:
PMC2637908
Abstract Full Text PDF–920K Supplementary Material
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