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J Virol. Aug 1990; 64(8): 4013–4015.
PMCID: PMC249702

Purification and characterization of a calicivirus as the causative agent of a lethal hemorrhagic disease in rabbits.


The causative viral agent of a lethal rabbit hemorrhagic disease has been purified and characterized. In negative-stained preparations, the virions were icosahedral, measured 27 to 35 nm in diameter, were without an envelope, and showed 10 peripheral cup-shaped depressions. The major structural protein was 60 kilodaltons, which constitutes a unique characteristic of the Caliciviridae.

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Selected References

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