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Ann R Coll Surg Engl. Jan 1983; 65(1): 20–23.
PMCID: PMC2494214

Angiography as an index of healing in experimental laparotomy wounds and colonic anastomoses.


The vascular anatomy of healing wounds in rat abdominal wall and obstructed large bowel was examined by sequential angiography, with particular reference to the possibility of tissue necrosis following mass closure of the abdominal wall and of dehiscence after primary anastomosis in obstructed colon. In the abdominal wall, gross distortion of the vascular anatomy one to two weeks after mass closure was accompanied by a central wound zone which had an appearance suggestive of necrosis. By the fourth week after closure vascular anatomy was restored and "necrosis" completely resolved. In left colon that had been acutely obstructed for 72 h an increased risk of anastomotic failure was accompanied by delays in the appearance of new vessels and their growth across the anastomosis, as detected by colonic angiography. Mass closure should not be discarded because of the hypothetical risk of tissue necrosis. Primary anastomosis in acutely obstructed colon is contra-indicated because of risk of delayed healing.

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Selected References

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  • Leaper DJ, Pollock AV, Evans M. Abdominal wound closure: a trial of nylon, polyglycolic acid and steel sutures. Br J Surg. 1977 Aug;64(8):603–606. [PubMed]
  • DRYE JC. Intraperitoneal pressure in the human. Surg Gynecol Obstet. 1948 Oct;87(4):472–475. [PubMed]
  • Goligher JC, Irvin TT, Johnston D, De Dombal FT, Hill GL, Horrocks JC. A controlled clinical trial of three methods of closure of laparotomy wounds. Br J Surg. 1975 Oct;62(10):823–829. [PubMed]
  • Debas HT, Thomson FB. A critical review of colectomy with anastomosis. Surg Gynecol Obstet. 1972 Nov;135(5):747–752. [PubMed]
  • Greenall MJ, Evans M, Pollock AV. Midline or transverse laparotomy? A random controlled clinical trial. Part I: Influence on healing. Br J Surg. 1980 Mar;67(3):188–190. [PubMed]
  • Adamsons RJ, Musco F, Enquist IF. The chemical dimensions of a healing incision. Surg Gynecol Obstet. 1966 Sep;123(3):515–521. [PubMed]
  • Rosin RD, Exarchakos G, Gilmore OJ, Ellis H. Topical noxythiolin in colonic healing. Br J Surg. 1978 Sep;65(9):603–606. [PubMed]
  • Savage PT. Immediate resection with end-to-end anastomosis for carcinoma of the colon presenting with acute intestinal obstruction. Proc R Soc Med. 1970;63 (Suppl):38–40. [PMC free article] [PubMed]
  • Fielding LP, Wells BW. Survival after primary and after staged resection for large bowel obstruction caused by cancer. Br J Surg. 1974 Jan;61(1):16–18. [PubMed]

Articles from Annals of The Royal College of Surgeons of England are provided here courtesy of The Royal College of Surgeons of England


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