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TIMP-2 mediates the anti-invasive effects of the nitric oxide-releasing prodrug JS-K in breast cancer cells
Ann-Marie Simeone, Vanity McMurtry, René Nieves-Alicea, Joseph E Saavedra, Larry K Keefer, Marcella M Johnson, Ana M Tari
Breast Cancer Res. 2008; 10(3): R44. Published online 2008 May 12. doi: 10.1186/bcr2095
PMCID:
PMC2481491
Abstract Full Text PDF–1.4M
 Is Cited by the Following 6 Articles in this Archive:
Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy
Jonathan M. Weiss, Lisa A. Ridnour, Tim Back, S. Perwez Hussain, Peijun He, Anna E. Maciag, Larry K. Keefer, William J. Murphy, Curtis C. Harris, David A. Wink, Robert H. Wiltrout
J Exp Med. 2010 October 25; 207(11): 2455–2467. doi: 10.1084/jem.20100670
PMCID:
PMC2964582
Abstract Full Text PDF–1.8M
Broad-Spectrum Anti-Cancer Activity of O2-Arylated Diazeniumdiolates
Larry K. Keefer, behalf of the JS-K Consortium
For Immunopathol Dis Therap. Author manuscript; available in PMC 2011 September 23.
Published in final edited form as: For Immunopathol Dis Therap. 2010 July 1; 1(3): 205–218. doi: 10.1615/ForumImmunDisTher.v1.i3.30
PMCID:
PMC3179376
Abstract Full Text PDF–671K
Stabilization of the Nitric Oxide (NO) Prodrugs and Anti-Cancer Leads, PABA/NO and Double JS-K through Incorporation into PEG-Protected Nanoparticles
Varun Kumar, Sam Y. Hong, Anna E. Maciag, Joseph E. Saavedra, Douglas H. Adamson, Robert K. Prud'homme, Larry K. Keefer, Harinath Chakrapani
Mol Pharm. Author manuscript; available in PMC 2011 February 1.
Published in final edited form as: Mol Pharm. 2010 February 1; 7(1): 291. doi: 10.1021/mp900245h
PMCID:
PMC2815019
Abstract Full Text PDF–1.1M
Synthesis and evaluation of piperazine and homopiperazine analogues of JS-K, an anti-cancer lead compound
Rahul S. Nandurdikar, Anna E. Maciag, Michael L. Citro, Paul J. Shami, Larry K. Keefer, Joseph E. Saavedra, Harinath Chakrapani
Bioorg Med Chem Lett. Author manuscript; available in PMC 2009 October 2.
Published in final edited form as: Bioorg Med Chem Lett. 2009 May 15; 19(10): 2760–2762. Published online 2009 March 28. doi: 10.1016/j.bmcl.2009.03.115
PMCID:
PMC2755573
Abstract Full Text PDF–274K Supplementary Material
Nitric Oxide Prodrug JS-K Inhibits Ubiquitin E1 and Kills Tumor Cells Retaining Wild Type p53
J Kitagaki, Y Yang, JE Saavedra, NH Colburn, LK Keefer, AO Perantoni
Oncogene. Author manuscript; available in PMC 2010 April 14.
Published in final edited form as: Oncogene. 2009 January 29; 28(4): 619–624. Published online 2008 November 3. doi: 10.1038/onc.2008.401
PMCID:
PMC2854646
Full Text PDF–1.9M
Adventitial transplantation of blood outgrowth endothelial cells in porcine haemodialysis grafts alleviates hypoxia and decreases neointimal proliferation through a matrix metalloproteinase-9-mediated pathway—a pilot study
Deborah Hughes, Alex A. Fu, Alessandra Puggioni, James F. Glockner, Bilal Anwer, Antonio M. McGuire, Debabrata Mukhopadhyay, Sanjay Misra
Nephrol Dial Transplant. 2009 January; 24(1): 85–96. Published online 2008 September 11. doi: 10.1093/ndt/gfn433
PMCID:
PMC2639314
Abstract Full Text PDF–1.4M
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