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Postgrad Med J. 1990 November; 66(781): 958–961.
PMCID: PMC2429747
Histiocytic cytophagic panniculitis.
D. A. Hilton, B. P. O'Malley, and S. T. Durrant
Department of Histopathology, Leicester Royal Infirmary, Infirmary Square, UK.
Abstract
A 33 year old man developed fever, malaise, jaundice, pancytopenia, coagulation abnormalities, hepatomegaly, pleural effusions and a subcutaneous lump. Biopsies revealed a lobular panniculitis with the presence of cytophagic histiocytes; erythrophagocytosis was also demonstrated in the liver and bone marrow. Despite the use of chemotherapy (CHOP) his clinical condition deteriorated and he died 5 months after presentation. This illness is consistent with the recently described syndrome of histiocytic cytophagic panniculitis.
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Selected References
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