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Postgrad Med J. 1979 Aug; 55(646): 541–545.
PMCID: PMC2428095

Pre-operative intravenous feeding--a controlled trial.


Seventy-four patients with a pre-operative diagnosis of stomach or oesophageal cancer were entered into a randomized, controlled clinical trial to assess the value of a short course of pre-operative intravenous nutrition. The effectiveness of this treatment was assessed by the clinical course and monitored by means of immune and biochemical profiles. Pre-operative parenteral nutrition given over a 7-10-day period resulted in a significant reduction in the incidence of postoperative wound infections. Clinical benefit was confined to those patients who had a low serum albumin on admission to hospital. It is doubtful whether this limited benefit justifies the routine use of intravenous feeding, with its attendant hazards, in the pre-operative preparation of patients with upper gastrointestinal cancer.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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  • Wardrop CA, Lewis MH, Tennant GB, Williams RH, Hughes LE. Acute folate deficiency associated with intravenous nutrition with aminoacid-sorbitol-ethanol: prophylaxis with intravenous folic acid. Br J Haematol. 1977 Dec;37(4):521–526. [PubMed]
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