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Postgrad Med J. 1991 Feb; 67(784): 195–197.
PMCID: PMC2398994

Sjögren-like pluriglandular exocrine insufficiency after drug-induced toxic epidermal necrolysis.


We present the case of a patient that progressively developed xerophthalmia, xerostomia, cutaneous xerosis and exocrine pancreatic insufficiency 3 months after metamizole-induced toxic epidermal necrolysis. Though the association of Sjögren's syndrome and exocrine pancreatic impairment is well established, the Sjögren-like syndrome after drug-induced toxic epidermal necrolysis in association with such a wide exocrine glandular insufficiency has not been previously described, to our knowledge.

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