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Protein interactions in human genetic diseases

Benjamin Schuster-Böckler, Alex Bateman

Genome Biol. 2008; 9(1): R9. Published online 2008 January 16. doi: 10.1186/gb-2008-9-1-r9

PMCID:: PMC2395246

Abstract Full Text PDF–1.4M Supplementary Material

Is Cited by the Following 10 Articles in this Archive:

Interactome Networks and Human Disease

Marc Vidal, Michael E. Cusick, Albert-László Barabási

Cell. Author manuscript; available in PMC 2012 March 18.

Published in final edited form as: Cell. 2011 March 18; 144(6): 986–998. doi: 10.1016/j.cell.2011.02.016

PMCID:: PMC3102045

Abstract Full Text PDF–300K

Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR

Nan Hao, Murray L. Whitelaw, Keith E. Shearwin, Ian B. Dodd, Anne Chapman-Smith

Nucleic Acids Res. 2011 May; 39(9): 3695–3709. Published online 2011 January 17. doi: 10.1093/nar/gkq1336

PMCID:: PMC3089468

Abstract Full Text PDF–9.8M Supplementary Material

Mechanisms of protein oligomerization, the critical role of insertions and deletions in maintaining different oligomeric states

Kosuke Hashimoto, Anna R. Panchenko

Proc Natl Acad Sci U S A. 2010 November 23; 107(47): 20352–20357. Published online 2010 November 3. doi: 10.1073/pnas.1012999107

PMCID:: PMC2996646

Abstract Full Text PDF–703K Supplementary Material

Evolution: A Guide to Perturb Protein Function and Networks

Olivier Lichtarge, Angela Wilkins

Curr Opin Struct Biol. Author manuscript; available in PMC 2011 June 1.

Published in final edited form as: Curr Opin Struct Biol. 2010 June; 20(3): 351–359. Published online 2010 May 3. doi: 10.1016/j.sbi.2010.04.002

PMCID:: PMC2916956

Abstract Full Text PDF–1.1M

Mutation@A Glance: An Integrative Web Application for Analysing Mutations from Human Genetic Diseases

Atsushi Hijikata, Rajesh Raju, Shivakumar Keerthikumar, Subhashri Ramabadran, Lavanya Balakrishnan, Suresh Kumar Ramadoss, Akhilesh Pandey, Sujatha Mohan, Osamu Ohara

DNA Res. 2010 June; 17(3): 197–208. Published online 2010 April 1. doi: 10.1093/dnares/dsq010

PMCID:: PMC2885273

Abstract Full Text PDF–563K Supplementary Material

Collaboratively charting the gene-to-phenotype network of human congenital heart defects

Roland Barriot, Jeroen Breckpot, Bernard Thienpont, Sylvain Brohée, Steven Van Vooren, Bert Coessens, Leon-Charles Tranchevent, Peter Van Loo, Marc Gewillig, Koenraad Devriendt, Yves Moreau

Genome Med. 2010; 2(3): 16. Published online 2010 March 1. doi: 10.1186/gm137

PMCID:: PMC2873794

Abstract Full Text PDF–1007K Supplementary Material

Edgetic perturbation models of human inherited disorders

Quan Zhong, Nicolas Simonis, Qian-Ru Li, Benoit Charloteaux, Fabien Heuze, Niels Klitgord, Stanley Tam, Haiyuan Yu, Kavitha Venkatesan, Danny Mou, Venus Swearingen, Muhammed A Yildirim, Han Yan, Amélie Dricot, David Szeto, Chenwei Lin, Tong Hao, Changyu Fan, Stuart Milstein, Denis Dupuy, Robert Brasseur, David E Hill, Michael E Cusick, Marc Vidal

Mol Syst Biol. 2009; 5: 321. Published online 2009 November 3. doi: 10.1038/msb.2009.80

PMCID:: PMC2795474

Abstract Full Text PDF–1.7M Supplementary Material

The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma

Cinzia Di Pietro, Marco Ragusa, Davide Barbagallo, Laura R Duro, Maria R Guglielmino, Alessandra Majorana, Rosario Angelica, Marina Scalia, Luisa Statello, Loredana Salito, Luisa Tomasello, Salvo Pernagallo, Salvo Valenti, Vito D'Agostino, Patrizio Triberio, Igor Tandurella, Giuseppe A Palumbo, Piera La Cava, Viviana Cafiso, Taschia Bertuccio, Maria Santagati, Giovanni Li Destri, Salvatore Lanzafame, Francesco Di Raimondo, Stefania Stefani, Bud Mishra, Michele Purrello

BMC Med Genomics. 2009; 2: 20. Published online 2009 April 30. doi: 10.1186/1755-8794-2-20