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Epidemiol Infect. Jun 1991; 106(3): 445–457.
PMCID: PMC2271871

Pharyngeal carriage of Neisseria meningitidis and Neisseria lactamica in households with infants within areas with high and low incidences of meningococcal disease.


In a household survey in the Faroe Islands, an isolated community with hyperendemic occurrence of meningococcal disease due to serogroup B 15, 1604 persons were examined for pharyngeal carriage of Neisseria meningitidis and N. lactamica. Two areas were chosen having experienced high (HIA), and two having experienced low incidences (LIA) of disease. Living in HIA compared with LIA was associated with higher risk of N. meningitidis B 15 carriage and lower risk of N. lactamica carriage, with odds ratios of 2.7 (95% confidence interval (CI) 1.4-5.1, P = 0.003) and 0.41 (95% CI 0.31-0.53, P less than 0.0001), respectively. In HIA the risk of N. meningitidis carriage was much lower in non-carriers than carriers of N. lactamica, with an odds ratio of 0.19 (95% CI 0.08-0.47, P = 0.0003); in LIA this association (odds ratio 0.51, P = 0.05) was much weaker. Children 0-14 years had substantially higher risk of being carriers of N. meningitidis group B 15 if the mothers were so, with an odds ratio of 11 (95% CI 4-29, P less than 0.0001).

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Selected References

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  • Broome CV. The carrier state: Neisseria meningitidis. J Antimicrob Chemother. 1986 Jul;18 (Suppl A):25–34. [PubMed]
  • Poolman JT, Lind I, Jónsdóttir K, Frøholm LO, Jones DM, Zanen HC. Meningococcal serotypes and serogroup B disease in north-west Europe. Lancet. 1986 Sep 6;2(8506):555–558. [PubMed]
  • Weihe P, Mathiassen B, Rasmussen JM, Petersen T, Isager H. An epidemic outbreak of group B meningococcal disease on the Faroe Islands. Scand J Infect Dis. 1988;20(3):291–296. [PubMed]
  • MANTEL N, HAENSZEL W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959 Apr;22(4):719–748. [PubMed]
  • Miettinen O. Estimability and estimation in case-referent studies. Am J Epidemiol. 1976 Feb;103(2):226–235. [PubMed]
  • Cartwright KA, Stuart JM, Jones DM, Noah ND. The Stonehouse survey: nasopharyngeal carriage of meningococci and Neisseria lactamica. Epidemiol Infect. 1987 Dec;99(3):591–601. [PMC free article] [PubMed]
  • Gold R, Goldschneider I, Lepow ML, Draper TF, Randolph M. Carriage of Neisseria meningitidis and Neisseria lactamica in infants and children. J Infect Dis. 1978 Feb;137(2):112–121. [PubMed]
  • Marks MI, Frasch CE, Shapera RM. Meningococcal colonization and infection in children and their household contacts. Am J Epidemiol. 1979 May;109(5):563–571. [PubMed]
  • Blakebrough IS, Greenwood BM, Whittle HC, Bradley AK, Gilles HM. The epidemiology of infections due to Neisseria meningitidis and Neisseria lactamica in a northern Nigerian community. J Infect Dis. 1982 Nov;146(5):626–637. [PubMed]
  • Stuart JM, Cartwright KA, Robinson PM, Noah ND. Effect of smoking on meningococcal carriage. Lancet. 1989 Sep 23;2(8665):723–725. [PubMed]
  • Saez-Nieto JA, Dominguez JR, Monton JL, Cristobal P, Fenoll A, Vazquez J, Casal J, Taracena B. Carriage of Neisseria meningitidis and Neisseria lactamica in a school population during an epidemic period in Spain. J Hyg (Lond) 1985 Jun;94(3):279–288. [PMC free article] [PubMed]
  • Saez-Nieto JA, Campos J, Latorre C, Juncosa T, Sierra M, Garcia-Tornell T, Garcia-Barreno B, Lopez-Galindez C, Casal J. Prevalence of Neisseria meningitidis in family members of patients with meningococcal infection. J Hyg (Lond) 1982 Aug;89(1):139–148. [PMC free article] [PubMed]

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