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Epidemiol Infect. Apr 1990; 104(2): 203–209.
PMCID: PMC2271764

Secretor status, smoking and carriage of Neisseria meningitidis.

Abstract

A survey of ABO blood groups, secretor status and smoking habits among 389 students and staff of a school in which there was an outbreak of meningococcal disease found no difference in the distribution of the ABO blood groups but a significantly higher proportion of non-secretors (37.6%) in the population examined compared with that reported for previous surveys of the neighbouring population in Glasgow (26.2%) (P less than 0.0005). There was also a significantly higher proportion of non-secretors among carriers of meningococci (47%) compared with non-carriers (32%). Increased carriage of meningococci among non-secretors might contribute to the increased susceptibility of individuals with this genetic characteristic to meningococcal disease observed in previous studies. Although passive exposure to cigarette smoke has been associated with meningococcal disease, there was no association between passive smoking and carriage. There was, however, a significant association between active smoking and carriage.

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Selected References

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  • Blackwell CC, Jónsdóttir K, Hanson M, Todd WT, Chaudhuri AK, Mathew B, Brettle RP, Weir DM. Non-secretion of ABO antigens predisposing to infection by Neisseria meningitidis and Streptococcus pneumoniae. Lancet. 1986 Aug 2;2(8501):284–285. [PubMed]
  • Blackwell CC, Weir DM, James VS, Cartwright KA, Stuart JM, Jones DM. The Stonehouse study: secretor status and carriage of Neisseria species. Epidemiol Infect. 1989 Feb;102(1):1–10. [PMC free article] [PubMed]
  • Stuart JM, Cartwright KA, Dawson JA, Rickard J, Noah ND. Risk factors for meningococcal disease: a case control study in south west England. Community Med. 1988 May;10(2):139–146. [PubMed]
  • Haneberg B, Tønjum T, Rodahl K, Gedde-Dahl TW. Factors preceding the onset of meningococcal disease, with special emphasis on passive smoking, symptoms of ill health. NIPH Ann. 1983 Dec;6(2):169–173. [PubMed]
  • Kaiser AB, Hennekens CH, Saslaw MS, Hayes PS, Bennett JV. Seroepidemiology and chemoprophylaxis disease due to sulfonamide-resistant Neisseria meningitidis in a civillian population. J Infect Dis. 1974 Sep;130(3):217–224. [PubMed]
  • Editorial: Straining, sitting, and squatting at stool. Lancet. 1975 Jul 5;2(7923):18–19. [PubMed]
  • Nichol KP, Cherry JD. Bacterial-viral interrelations in respiratory infections of children. N Engl J Med. 1967 Sep 28;277(13):667–672. [PubMed]
  • EICHENWALD HF, KOTSEVALOV O, FASSO LA. Some effects of viral infection on aerial dissemination of staphylococci and on susceptibility to bacterial colonization. Bacteriol Rev. 1961 Sep;25:274–281. [PMC free article] [PubMed]
  • Krasinski K, Nelson JD, Butler S, Luby JP, Kusmiesz H. Possible association of mycoplasma and viral respiratory infections with bacterial meningitis. Am J Epidemiol. 1987 Mar;125(3):499–508. [PubMed]
  • Kinane DF, Blackwell CC, Brettle RP, Weir DM, Winstanley FP, Elton RA. ABO blood group, secretor state, and susceptibility to recurrent urinary tract infection in women. Br Med J (Clin Res Ed) 1982 Jul 3;285(6334):7–9. [PMC free article] [PubMed]
  • MACSWEEN MP, SYME UA. ABO BLOOD GROUPS AND SKIN DISEASES. Br J Dermatol. 1965 Jan;77:30–34. [PubMed]
  • CAMERON JM. Blood-groups in tumours of salivary tissue. Lancet. 1958 Feb 1;1(7014):239–240. [PubMed]
  • Stuart JM, Cartwright KA, Jones DM, Noah ND, Wall RJ, Blackwell CC, Jephcott AE, Ferguson IR. An outbreak of meningococcal disease in Stonehouse: planning and execution of a large-scale survey. Epidemiol Infect. 1987 Dec;99(3):579–589. [PMC free article] [PubMed]
  • Cartwright KA, Stuart JM, Jones DM, Noah ND. The Stonehouse survey: nasopharyngeal carriage of meningococci and Neisseria lactamica. Epidemiol Infect. 1987 Dec;99(3):591–601. [PMC free article] [PubMed]
  • Haverkorn MJ, Goslings WR. Streptococci, ABO blood groups, and secretor status. Am J Hum Genet. 1969 Jul;21(4):360–375. [PMC free article] [PubMed]
  • Burford-Mason AP, Weber JC, Willoughby JM. Oral carriage of Candida albicans, ABO blood group and secretor status in healthy subjects. J Med Vet Mycol. 1988 Feb;26(1):49–56. [PubMed]

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