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Using protein complexes to predict phenotypic effects of gene mutation
Hunter B Fraser, Joshua B Plotkin
Genome Biol. 2007; 8(11): R252. Published online 2007 November 27. doi: 10.1186/gb-2007-8-11-r252
PMCID:
PMC2258176
Abstract Full Text PDF–560K Supplementary Material

Is Cited by the Following 21 Articles in this Archive:

Modularity in Protein Complex and Drug Interactions Reveals New Polypharmacological Properties
Jose C. Nacher, Jean-Marc Schwartz
PLoS One. 2012; 7(1): e30028. Published online 2012 January 18. doi: 10.1371/journal.pone.0030028
PMCID:
PMC3261189
Abstract Full Text PDF–1.9M Supplementary Material
Prioritizing candidate disease genes by network-based boosting of genome-wide association data
Insuk Lee, U. Martin Blom, Peggy I. Wang, Jung Eun Shim, Edward M. Marcotte
Genome Res. 2011 July; 21(7): 1109–1121. doi: 10.1101/gr.118992.110
PMCID:
PMC3129253
Abstract Full Text PDF–1.3M
Genome-Wide Survey of Natural Selection on Functional, Structural, and Network Properties of Polymorphic Sites in Saccharomyces paradoxus
Anchal Vishnoi, Praveen Sethupathy, Daniel Simola, Joshua B. Plotkin, Sridhar Hannenhalli
Mol Biol Evol. 2011 September; 28(9): 2615–2627. Published online 2011 April 3. doi: 10.1093/molbev/msr085
PMCID:
PMC3203547
Free in PMC on 2012/09/01
Interactome Networks and Human Disease
Marc Vidal, Michael E. Cusick, Albert-László Barabási
Cell. Author manuscript; available in PMC 2012 March 18.
Published in final edited form as: Cell. 2011 March 18; 144(6): 986–998. doi: 10.1016/j.cell.2011.02.016
PMCID:
PMC3102045
Abstract Full Text PDF–300K
Networked-based Characterization of Extracellular Matrix Proteins from Adult Mouse Pulmonary and Aortic Valves
Peggi M. Angel, David Nusinow, Chris B. Brown, Kate Violette, Joey V. Barnett, Bing Zhang, H. Scott Baldwin, Richard M. Caprioli
J Proteome Res. Author manuscript; available in PMC 2011 July 19.
Published in final edited form as: J Proteome Res. 2011 February 4; 10(2): 812–823. Published online 2010 December 22. doi: 10.1021/pr1009806
PMCID:
PMC3139330
Abstract Full Text PDF–2.2M Supplementary Material
A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae
Oriol Gallego, Matthew J Betts, Jelena Gvozdenovic-Jeremic, Kenji Maeda, Christian Matetzki, Carmen Aguilar-Gurrieri, Pedro Beltran-Alvarez, Stefan Bonn, Carlos Fernández-Tornero, Lars Juhl Jensen, Michael Kuhn, Jamie Trott, Vladimir Rybin, Christoph W Müller, Peer Bork, Marko Kaksonen, Robert B Russell, Anne-Claude Gavin
Mol Syst Biol. 2010; 6: 430. Published online 2010 November 30. doi: 10.1038/msb.2010.87
PMCID:
PMC3010107
Abstract Full Text PDF–1.6M Supplementary Material
Predicting genetic modifier loci using functional gene networks
Insuk Lee, Ben Lehner, Tanya Vavouri, Junha Shin, Andrew G. Fraser, Edward M. Marcotte
Genome Res. 2010 August; 20(8): 1143–1153. doi: 10.1101/gr.102749.109
PMCID:
PMC2909577
Abstract Full Text PDF–1.1M
It’s the machine that matters: Predicting gene function and phenotype from protein networks
Peggy I. Wang, Edward M. Marcotte
J Proteomics. Author manuscript; available in PMC 2011 October 10.
Published in final edited form as: J Proteomics. 2010 October 10; 73(11): 2277–2289. Published online 2010 July 15. doi: 10.1016/j.jprot.2010.07.005
PMCID:
PMC2953423
Abstract Full Text PDF–4.2M
Functional and evolutionary correlates of gene constellations in the Drosophila melanogaster genome that deviate from the stereotypical gene architecture
Shuwei Li, Ching-Hua Shih, Michael H Kohn
BMC Genomics. 2010; 11: 322. Published online 2010 May 24. doi: 10.1186/1471-2164-11-322
PMCID:
PMC2891614
Abstract Full Text PDF–1.4M Supplementary Material
The Type 1 Diabetes - HLA Susceptibility Interactome - Identification of HLA Genotype-Specific Disease Genes for Type 1 Diabetes
Caroline Brorsson, Niclas Tue Hansen, Regine Bergholdt, Søren Brunak, Flemming Pociot
PLoS One. 2010; 5(3): e9576. Published online 2010 March 5. doi: 10.1371/journal.pone.0009576
PMCID:
PMC2832689
Abstract Full Text PDF–408K
The power of protein interaction networks for associating genes with diseases
Saket Navlakha, Carl Kingsford
Bioinformatics. 2010 April 15; 26(8): 1057–1063. Published online 2010 February 24. doi: 10.1093/bioinformatics/btq076
PMCID:
PMC2853684
Abstract Full Text PDF–433K Supplementary Material
Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana
Insuk Lee, Bindu Ambaru, Pranjali Thakkar, Edward M. Marcotte, Seung Y. Rhee
Nat Biotechnol. Author manuscript; available in PMC 2010 April 20.
Published in final edited form as: Nat Biotechnol. 2010 February; 28(2): 149–156. Published online 2010 January 31. doi: 10.1038/nbt.1603
PMCID:
PMC2857375
Abstract Full Text PDF–2.5M Supplementary Material
Toward the dynamic interactome: it's about time
Teresa M. Przytycka, Mona Singh, Donna K. Slonim
Brief Bioinform. 2010 January; 11(1): 15–29. Published online 2010 January 8. doi: 10.1093/bib/bbp057
PMCID:
PMC2810115
Abstract Full Text PDF–151K
Discovering cancer genes by integrating network and functional properties
Li Li, Kangyu Zhang, James Lee, Shaun Cordes, David P Davis, Zhijun Tang
BMC Med Genomics. 2009; 2: 61. Published online 2009 September 19. doi: 10.1186/1755-8794-2-61
PMCID:
PMC2758898
Abstract Full Text PDF–1.0M Supplementary Material
Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network
Bolan Linghu, Evan S Snitkin, Zhenjun Hu, Yu Xia, Charles DeLisi
Genome Biol. 2009; 10(9): R91. Published online 2009 September 3. doi: 10.1186/gb-2009-10-9-r91
PMCID:
PMC2768980
Abstract Full Text PDF–676K Supplementary Material
Linking genes to diseases: it's all in the data
Nicki Tiffin, Miguel A Andrade-Navarro, Carolina Perez-Iratxeta
Genome Med. 2009; 1(8): 77. Published online 2009 August 7. doi: 10.1186/gm77
PMCID:
PMC2768963
Abstract Full Text PDF–216K
Expression Profiling of Human Genetic and Protein Interaction Networks in Type 1 Diabetes
Regine Bergholdt, Caroline Brorsson, Kasper Lage, Jens Høiriis Nielsen, Søren Brunak, Flemming Pociot
PLoS One. 2009; 4(7): e6250. Published online 2009 July 17. doi: 10.1371/journal.pone.0006250
PMCID:
PMC2707614
Abstract Full Text PDF–435K
Translational disease interpretation with molecular networks
Anaïs Baudot, Gonzalo Gómez-López, Alfonso Valencia
Genome Biol. 2009; 10(6): 221. Published online 2009 June 29. doi: 10.1186/gb-2009-10-6-221
PMCID:
PMC2718486
Abstract Full Text PDF–592K
An evolutionary and structural characterization of mammalian protein complex organization
Philip Wong, Sonja Althammer, Andrea Hildebrand, Andreas Kirschner, Philipp Pagel, Bernd Geissler, Pawel Smialowski, Florian Blöchl, Matthias Oesterheld, Thorsten Schmidt, Normann Strack, Fabian J Theis, Andreas Ruepp, Dmitrij Frishman
BMC Genomics. 2008; 9: 629. Published online 2008 December 23. doi: 10.1186/1471-2164-9-629
PMCID:
PMC2645396
Abstract Full Text PDF–1.1M Supplementary Material
Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality
Elena Zotenko, Julian Mestre, Dianne P. O'Leary, Teresa M. Przytycka
PLoS Comput Biol. 2008 August; 4(8): e1000140. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000140
PMCID:
PMC2467474
Abstract Full Text PDF–870K Supplementary Material
Network-based global inference of human disease genes
Xuebing Wu, Rui Jiang, Michael Q Zhang, Shao Li
Mol Syst Biol. 2008; 4: 189. Published online 2008 May 6. doi: 10.1038/msb.2008.27
PMCID:
PMC2424293
Abstract Full Text PDF–3.2M Supplementary Material
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