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Clin Exp Immunol. 1996 Jun; 104(3): 543–546.
PMCID: PMC2200461

90K (Mac-2 BP) in human milk


Human 90K, also known as Mac-2 binding protein (Mac-2 BP), is a secreted glycoprotein which is widely expressed, binds to the human macrophage-associated lectin Mac-2, and may have a role in host defence. We have measured the concentrations of 90K in human breast milk from eight healthy mothers delivering mature healthy infants after full-term pregnancy using a specific immunoenzymatic assay. Maximal 90K concentrations were observed on days 2–3 post-partum, and ranged from 13.4 to 79.2 μg/ml. The concentrations of 90K in the milk had no correlation with those in the maternal blood.

Keywords: newborn, host defence, gastrointestinal infection

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