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J Cell Biol. Aug 1, 1995; 130(3): 503–506.
PMCID: PMC2120533

Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1

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Selected References

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  • Adams J, Lawler J. Extracellular matrix: the thrombospondin family. Curr Biol. 1993 Mar;3(3):188–190. [PubMed]
  • Bornstein P. Thrombospondins: structure and regulation of expression. FASEB J. 1992 Nov;6(14):3290–3299. [PubMed]
  • Bornstein P, Sage EH. Thrombospondins. Methods Enzymol. 1994;245:62–85. [PubMed]
  • Castle VP, Ou X, O'Rourke K, Dixit VM. High level thrombospondin 1 expression in two NIH 3T3 cloned lines confers serum- and anchorage-independent growth. J Biol Chem. 1993 Feb 5;268(4):2899–2903. [PubMed]
  • Castle V, Varani J, Fligiel S, Prochownik EV, Dixit V. Antisense-mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma. J Clin Invest. 1991 Jun;87(6):1883–1888. [PMC free article] [PubMed]
  • Corless CL, Mendoza A, Collins T, Lawler J. Colocalization of thrombospondin and syndecan during murine development. Dev Dyn. 1992 Apr;193(4):346–358. [PubMed]
  • Dameron KM, Volpert OV, Tainsky MA, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science. 1994 Sep 9;265(5178):1582–1584. [PubMed]
  • Erickson HP. Gene knockouts of c-src, transforming growth factor beta 1, and tenascin suggest superfluous, nonfunctional expression of proteins. J Cell Biol. 1993 Mar;120(5):1079–1081. [PMC free article] [PubMed]
  • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med. 1995 Jan;1(1):27–31. [PubMed]
  • Good DJ, Polverini PJ, Rastinejad F, Le Beau MM, Lemons RS, Frazier WA, Bouck NP. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci U S A. 1990 Sep;87(17):6624–6628. [PMC free article] [PubMed]
  • Hogg PJ. Thrombospondin 1 as an enzyme inhibitor. Thromb Haemost. 1994 Dec;72(6):787–792. [PubMed]
  • Iruela-Arispe ML, Bornstein P, Sage H. Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro. Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):5026–5030. [PMC free article] [PubMed]
  • Iruela-Arispe ML, Liska DJ, Sage EH, Bornstein P. Differential expression of thrombospondin 1, 2, and 3 during murine development. Dev Dyn. 1993 May;197(1):40–56. [PubMed]
  • Laherty CD, O'Rourke K, Wolf FW, Katz R, Seldin MF, Dixit VM. Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development. J Biol Chem. 1992 Feb 15;267(5):3274–3281. [PubMed]
  • Liska DJ, Hawkins R, Wikstrom K, Bornstein P. Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells. J Cell Physiol. 1994 Mar;158(3):495–505. [PubMed]
  • Majack RA, Mildbrandt J, Dixit VM. Induction of thrombospondin messenger RNA levels occurs as an immediate primary response to platelet-derived growth factor. J Biol Chem. 1987 Jun 25;262(18):8821–8825. [PubMed]
  • Marinides GN, Suchard SJ, Mookerjee BK. Role of thrombospondin in mesangial cell growth: possible existence of an autocrine feedback growth circuit. Kidney Int. 1994 Aug;46(2):350–357. [PubMed]
  • Nickoloff BJ, Mitra RS, Varani J, Dixit VM, Polverini PJ. Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis. Am J Pathol. 1994 Apr;144(4):820–828. [PMC free article] [PubMed]
  • Nicosia RF, Tuszynski GP. Matrix-bound thrombospondin promotes angiogenesis in vitro. J Cell Biol. 1994 Jan;124(1-2):183–193. [PMC free article] [PubMed]
  • O'Rourke KM, Laherty CD, Dixit VM. Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers. J Biol Chem. 1992 Dec 15;267(35):24921–24924. [PubMed]
  • Pellerin S, Lafeuillade B, Chambaz EM, Feige JJ. Distinct effects of thrombospondin-1 and CISP/thrombospondin-2 on adrenocortical cell spreading. Mol Cell Endocrinol. 1994 Dec;106(1-2):181–186. [PubMed]
  • Saga Y, Yagi T, Ikawa Y, Sakakura T, Aizawa S. Mice develop normally without tenascin. Genes Dev. 1992 Oct;6(10):1821–1831. [PubMed]
  • Sage EH, Bornstein P. Extracellular proteins that modulate cell-matrix interactions. SPARC, tenascin, and thrombospondin. J Biol Chem. 1991 Aug 15;266(23):14831–14834. [PubMed]
  • Sandler MA, Zhang JN, Westerhausen DR, Jr, Billadello JJ. A novel protein interacts with the major transforming growth factor-beta responsive element in the plasminogen activator inhibitor type-1 gene. J Biol Chem. 1994 Aug 26;269(34):21500–21504. [PubMed]
  • Schultz-Cherry S, Ribeiro S, Gentry L, Murphy-Ullrich JE. Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined system. J Biol Chem. 1994 Oct 28;269(43):26775–26782. [PubMed]
  • Sherbina NV, Bornstein P. Modulation of thrombospondin gene expression during osteoblast differentiation in MC3T3-E1 cells. Bone. 1992;13(2):197–201. [PubMed]
  • Sun X, Skorstengaard K, Mosher DF. Disulfides modulate RGD-inhibitable cell adhesive activity of thrombospondin. J Cell Biol. 1992 Aug;118(3):693–701. [PMC free article] [PubMed]
  • Tolsma SS, Volpert OV, Good DJ, Frazier WA, Polverini PJ, Bouck N. Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity. J Cell Biol. 1993 Jul;122(2):497–511. [PMC free article] [PubMed]
  • Vogel T, Guo NH, Krutzsch HC, Blake DA, Hartman J, Mendelovitz S, Panet A, Roberts DD. Modulation of endothelial cell proliferation, adhesion, and motility by recombinant heparin-binding domain and synthetic peptides from the type I repeats of thrombospondin. J Cell Biochem. 1993 Sep;53(1):74–84. [PubMed]
  • Weinstat-Saslow DL, Zabrenetzky VS, VanHoutte K, Frazier WA, Roberts DD, Steeg PS. Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis. Cancer Res. 1994 Dec 15;54(24):6504–6511. [PubMed]
  • Zabrenetzky V, Harris CC, Steeg PS, Roberts DD. Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines. Int J Cancer. 1994 Oct 15;59(2):191–195. [PubMed]

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