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J Cell Biol. 1966 Jun 1; 29(3): 507–523.
PMCID: PMC2106972


Dry Mass, Wet Mass, Volume, and Concentration of Solids


The dry mass, wet mass, and volume of mitochondria of normal rat liver were determined, as well as nitrogen content and concentration. A scheme of multiple approaches to these quantities was devised, permitting comparison of values obtained by independent methods. The following basic values are considered highly accurate: Mean dry mass, 13.6 x 10-14 g; mean wet mass, 51.8 x 10-14 g; mean volume, 0.43 µ3; nitrogen content, 1.75 x 10-14 g The work emphasizes the fact that in mitochondria the quantities, mass, and volume occur in logarithmic-normal distributions.

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Selected References

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  • Bahr GF, Herbener GH, Glas U. A method for the counting of mitochondria. Exp Cell Res. 1966 Jan;41(1):99–108. [PubMed]
  • BAHR GF, ZEITLER E. Study of mitochondria in rat liver. Quantitative electron microscopy. J Cell Biol. 1962 Dec;15:489–501. [PMC free article] [PubMed]
  • Glas U, Bahr GF. A simple method for the determination of water content and protein concentration in subcellular elements. J Histochem Cytochem. 1966 Jan;14(1):40–44. [PubMed]
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