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J Cell Biol. Mar 1, 1963; 16(3): 541–577.
PMCID: PMC2106229

THE FINE STRUCTURE OF THE GASTRIC MUCOSA IN THE BAT

Abstract

A description of the cytology of the gastric mucosa is presented based upon an electron microscopic investigation of the bat stomach. The fine structure of the various cell types in this species is fundamentally similar to that of the corresponding cell types of other mammals, but the relative cell numbers and distribution are somewhat different. (a). The surface mucous cells are identified by their superficial location and by the character of their dense secretory granules. (b). The mucous neck cells are distinguished by a characteristically different appearance and distribution of their mucous granules, and by their varied shape and their location between parietal cells. (c). The parietal cells are very large and have unusually prominent secretory canaliculi and an extraordinary number of large mitochondria. (d). The chief cells are found at the base of the gastric glands and are similar in their fine structure to other zymogenic cells. They contain many large zymogen granules and have an extensively developed granular endoplasmic reticulum. The latter is sometimes aggregated in unusual, hexagonally packed straight tubules, each with twelve longitudinal rows of ribosomes uniformly spaced around its circumference and with the rows of ribosomes in precise register with those of adjoining tubules. (e). Argentaffin cells lodged between other cell types vary sufficiently in the structure of their mitochondria and the character of their specific granules to suggest that they are of more than one kind. The majority are at the base of the epithelium but some extend to the lumen and bear microvilli on their free surface.

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Selected References

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  • BURTNER HJ, LILLIE RD. A 5-hour variant of Gomori's methenamine silver method for argentaffin cells. Stain Technol. 1949 Oct;24(4):225–227. [PubMed]
  • HALLY AD. The fine structure of the gastric parietal cell in the mouse. J Anat. 1959 Apr;93(2):217–225. [PMC free article] [PubMed]
  • HALLY AD. Functional changes in the vacuole-containing bodies of the gastric parietal cell. Nature. 1959 Feb 7;183(4658):408–408. [PubMed]
  • HELANDER HF. A preliminary note on the ultrastructure of the argyrophile cells of the mouse gastric mucosa. J Ultrastruct Res. 1961 Jun;5:257–262. [PubMed]
  • HELANDER H, EKHOLM R. Ultrastructure of epithelial cells in the fundus glands of the mouse gastric mucosa. J Ultrastruct Res. 1959 Oct;3:74–83. [PubMed]
  • HELLWEG G. Uber Vorkommen und gegenseitiges Verhalten der argentaffinen und argyrophilen Zellen im menschlichen Magen-Darm-Trakt. Z Zellforsch Mikrosk Anat. 1952;36(6):546–551. [PubMed]
  • KARNOVSKY MJ. Simple methods for "staining with lead" at high pH in electron microscopy. J Biophys Biochem Cytol. 1961 Dec;11:729–732. [PMC free article] [PubMed]
  • KUROSUMI K. Electron microscopic analysis of the secretion mechanism. Int Rev Cytol. 1961;11:1–124. [PubMed]
  • LACY PE. Electron microscopic identification of different cell types in the islets of Langerhans of the guinea pig, rat, rabbit and dog. Anat Rec. 1957 Jun;128(2):255–267. [PubMed]
  • LAWN AM. Observations on the fine structure of the gastric parietal cell of the rat. J Biophys Biochem Cytol. 1960 Feb;7:161–166. [PMC free article] [PubMed]
  • PEACHEY LD, RASMUSSEN H. Structure of the toad's urinary bladder as related to its physiology. J Biophys Biochem Cytol. 1961 Aug;10:529–553. [PMC free article] [PubMed]
  • RICHARDSON KC, JARETT L, FINKE EH. Embedding in epoxy resins for ultrathin sectioning in electron microscopy. Stain Technol. 1960 Nov;35:313–323. [PubMed]
  • STEVENS CE, LEBLOND CP. Renewal of the mucous cells in the gastric mucosa of the rat. Anat Rec. 1953 Feb;115(2):231–245. [PubMed]
  • TRUMP BF, SMUCKLER EA, BENDITT EP. A method for staining epoxy sections for light microscopy. J Ultrastruct Res. 1961 Aug;5:343–348. [PubMed]
  • VIAL JD, ORREGO H. Electron microscope observations on the fine structure of parietal cells. J Biophys Biochem Cytol. 1960 Apr;7:367–372. [PMC free article] [PubMed]
  • WATSON ML. Staining of tissue sections for electron microscopy with heavy metals. II. Application of solutions containing lead and barium. J Biophys Biochem Cytol. 1958 Nov 25;4(6):727–730. [PMC free article] [PubMed]
  • YAMADA E. The fine structure of the gall bladder epithelium of the mouse. J Biophys Biochem Cytol. 1955 Sep 25;1(5):445–458. [PMC free article] [PubMed]

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