• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of nihpaAbout Author manuscriptsSubmit a manuscriptNIH Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
PMC full text:
AJNR Am J Neuroradiol. Author manuscript; available in PMC Nov 29, 2007.
Published in final edited form as:
AJNR Am J Neuroradiol. 2006; 27(6): 1230–1233.

Fig 1

An external file that holds a picture, illustration, etc.
Object name is nihms33908f1.jpg

Eye-of-the-tiger sign (arrows). This 10-year-old boy with the PANK2 mutation shows MR features characteristic of PKAN. The T1-weighted images appear normal, but high signal intensity can be seen in the globus pallidus on proton attenuation (PD), T2-weighted fluid-attenuated inversion recovery (FLAIR), and T2-weighted images in both the axial and coronal planes. With increasingly heavier T2 weighting (PD<FLAIR<T2), there is increasingly conspicuous T2 hypointensity at the periphery because of the magnetic susceptibility effects of excess iron.

Images in this article

  • Fig 1
  • Fig 2
Click on the image to see a larger version.