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World Antimalarial Resistance Network (WARN) III: Molecular markers for drug resistant malaria
Christopher V Plowe, Cally Roper, John W Barnwell, Christian T Happi, Hema H Joshi, Wilfred Mbacham, Steven R Meshnick, Kefas Mugittu, Inbarani Naidoo, Ric N Price, Robert W Shafer, Carol H Sibley, Colin J Sutherland, Peter A Zimmerman, Philip J Rosenthal
Malar J. 2007; 6: 121. Published online 2007 September 6. doi: 10.1186/1475-2875-6-121
PMCID:
PMC2008207
Abstract Full Text PDF–536K
 Is Cited by the Following 23 Articles in this Archive:
Development of a TaqMan Allelic Discrimination Assay for detection of Single Nucleotides Polymorphisms associated with anti-malarial drug resistance
Edwin Kamau, Saba Alemayehu, Karla C Feghali, LaDonna S Tolbert, Bernard Ogutu, Christian F Ockenhouse
Malar J. 2012; 11: 23. Published online 2012 January 20. doi: 10.1186/1475-2875-11-23
PMCID:
PMC3273427
Abstract Full Text PDF–1.2M
A new high-throughput method for simultaneous detection of drug resistance associated mutations in Plasmodium vivax dhfr, dhps and mdr1 genes
Céline Barnadas, David Kent, Lincoln Timinao, Jonah Iga, Laurie R Gray, Peter Siba, Ivo Mueller, Peter J Thomas, Peter A Zimmerman
Malar J. 2011; 10: 282. Published online 2011 September 24. doi: 10.1186/1475-2875-10-282
PMCID:
PMC3192712
Abstract Full Text PDF–577K Supplementary Material
Molecular markers of anti-malarial drug resistance in Lahj Governorate, Yemen: baseline data and implications
Reem A Mubjer, Ahmed A Adeel, Michael L Chance, Amir A Hassan
Malar J. 2011; 10: 245. Published online 2011 August 21. doi: 10.1186/1475-2875-10-245
PMCID:
PMC3177815
Abstract Full Text PDF–315K
In vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na+/H+ exchanger (Pfnhe-1) gene: the absence of association in clinical isolates from the Republic of Congo
Sébastien Briolant, Stéphane Pelleau, Hervé Bogreau, Philippe Hovette, Agnès Zettor, Jacky Castello, Eric Baret, Rémy Amalvict, Christophe Rogier, Bruno Pradines
Malar J. 2011; 10: 37. Published online 2011 February 11. doi: 10.1186/1475-2875-10-37
PMCID:
PMC3055222
Abstract Full Text PDF–347K
How can we identify parasite genes that underlie antimalarial drug resistance?
Tim Anderson, Standwell Nkhoma, Andrea Ecker, David Fidock
Pharmacogenomics. Author manuscript; available in PMC 2011 November 1.
Published in final edited form as: Pharmacogenomics. 2011 January; 12(1): 59–85. doi: 10.2217/pgs.10.165
PMCID:
PMC3148835
Abstract Full Text PDF–1.7M
Limited Ability of Plasmodium falciparum pfcrt, pfmdr1, and pfnhe1 Polymorphisms To Predict Quinine In Vitro Sensitivity or Clinical Effectiveness in Uganda
Frederick N. Baliraine, Samuel L. Nsobya, Jane Achan, James K. Tibenderana, Ambrose O. Talisuna, Bryan Greenhouse, Philip J. Rosenthal
Antimicrob Agents Chemother. 2011 February; 55(2): 615–622. Published online 2010 November 15. doi: 10.1128/AAC.00954-10
PMCID:
PMC3028814
Abstract Full Text PDF–1.2M
A Comparison of Methods to Detect and Quantify the Markers of Antimalarial Drug Resistance
Ian M. Hastings, Christian Nsanzabana, Tom A. Smith
Am J Trop Med Hyg. 2010 September; 83(3): 489–495. doi: 10.4269/ajtmh.2010.10-0072
PMCID:
PMC2929039
Abstract Full Text PDF–592K Supplementary Material
Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations
Sankar Sridaran, Shannon K McClintock, Luke M Syphard, Karen M Herman, John W Barnwell, Venkatachalam Udhayakumar
Malar J. 2010; 9: 247. Published online 2010 August 30. doi: 10.1186/1475-2875-9-247
PMCID:
PMC2940896
Abstract Full Text PDF–1.3M Supplementary Material
Plasmodium falciparum resistance to anti-malarial drugs in Papua New Guinea: evaluation of a community-based approach for the molecular monitoring of resistance
Jutta Marfurt, Thomas A Smith, Ian M Hastings, Ivo Müller, Albert Sie, Olive Oa, Moses Baisor, John C Reeder, Hans-Peter Beck, Blaise Genton
Malar J. 2010; 9: 8. Published online 2010 January 7. doi: 10.1186/1475-2875-9-8
PMCID:
PMC2820042
Abstract Full Text PDF–485K Supplementary Material
Molecular Genomic Approaches to Infectious Diseases in Resource-Limited Settings
Josefina Coloma, Eva Harris
PLoS Med. 2009 October; 6(10): e1000142. Published online 2009 October 26. doi: 10.1371/journal.pmed.1000142
PMCID:
PMC2745561
Full Text PDF–202K
FlexiChip package: an universal microarray with a dedicated analysis software for high-thoughput SNPs detection linked to anti-malarial drug resistance
Nicolas Steenkeste, Marie-Agnès Dillies, Nimol Khim, Odile Sismeiro, Sophy Chy, Pharath Lim, Andreas Crameri, Christiane Bouchier, Odile Mercereau-Puijalon, Hans-Peter Beck, Mallika Imwong, Arjen M Dondorp, Duong Socheat, Christophe Rogier, Jean-Yves Coppée, Frédéric Ariey
Malar J. 2009; 8: 229. Published online 2009 October 15. doi: 10.1186/1475-2875-8-229
PMCID:
PMC2770542
Abstract Full Text PDF–608K Supplementary Material
Plasmodium falciparum Drug Resistance in Madagascar: Facing the Spread of Unusual pfdhfr and pfmdr-1 Haplotypes and the Decrease of Dihydroartemisinin Susceptibility
Valérie Andriantsoanirina, Arsène Ratsimbasoa, Christiane Bouchier, Martial Jahevitra, Stéphane Rabearimanana, Rogelin Radrianjafy, Voahangy Andrianaranjaka, Tantely Randriantsoa, Marie Ange Rason, Magali Tichit, Léon Paul Rabarijaona, Odile Mercereau-Puijalon, Rémy Durand, Didier Ménard
Antimicrob Agents Chemother. 2009 November; 53(11): 4588–4597. Published online 2009 August 24. doi: 10.1128/AAC.00610-09
PMCID:
PMC2772329
Abstract Full Text PDF–1.8M
Efficacy of sulphadoxine-pyrimethamine with or without artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in southern Mozambique: a randomized controlled trial
Elizabeth N Allen, Francesca Little, Tunisio Camba, Yasmin Cassam, Jaishree Raman, Andrew Boulle, Karen I Barnes
Malar J. 2009; 8: 141. Published online 2009 June 26. doi: 10.1186/1475-2875-8-141
PMCID:
PMC2709115
Abstract Full Text PDF–544K
A systematic review and meta-analysis of evidence for correlation between molecular markers of parasite resistance and treatment outcome in falciparum malaria
Stéphane Picot, Piero Olliaro, Frédérique de Monbrison, Anne-Lise Bienvenu, Ric N Price, Pascal Ringwald
Malar J. 2009; 8: 89. Published online 2009 May 4. doi: 10.1186/1475-2875-8-89
PMCID:
PMC2681474
Abstract Full Text PDF–440K
Short Report: Novel dhps and pfcrt Polymorphisms in Plasmodium falciparum Detected by Heteroduplex Tracking Assay
Jonathan J. Juliano, David J. Bacon, Jianbing Mu, Xinhua Wang, Steven R. Meshnick
Am J Trop Med Hyg. Author manuscript; available in PMC 2010 May 1.
Published in final edited form as: Am J Trop Med Hyg. 2009 May; 80(5): 734–736.
PMCID:
PMC2755572
Abstract Full Text PDF–572K
Multiple Origins and Regional Dispersal of Resistant dhps in African Plasmodium falciparum Malaria
Richard J. Pearce, Hirva Pota, Marie-Solange B. Evehe, El-Hadj Bâ, Ghyslain Mombo-Ngoma, Allen L. Malisa, Rosalynn Ord, Walter Inojosa, Alexandre Matondo, Diadier A. Diallo, Wilfred Mbacham, Ingrid V. van den Broek, Todd D. Swarthout, Asefaw Getachew, Seyoum Dejene, Martin P. Grobusch, Fanta Njie, Samuel Dunyo, Margaret Kweku, Seth Owusu-Agyei, Daniel Chandramohan, Maryline Bonnet, Jean-Paul Guthmann, Sian Clarke, Karen I. Barnes, Elizabeth Streat, Stark T. Katokele, Petrina Uusiku, Chris O. Agboghoroma, Olufunmilayo Y. Elegba, Badara Cissé, Ishraga E. A-Elbasit, Hayder A. Giha, S. Patrick Kachur, Caroline Lynch, John B. Rwakimari, Pascalina Chanda, Moonga Hawela, Brian Sharp, Inbarani Naidoo, Cally Roper
PLoS Med. 2009 April; 6(4): e1000055. Published online 2009 April 14. doi: 10.1371/journal.pmed.1000055
PMCID:
PMC2661256
Abstract Full Text PDF–850K Supplementary Material
Nonradioactive heteroduplex tracking assay for the detection of minority-variant chloroquine-resistant Plasmodium falciparum in Madagascar
Jonathan J Juliano, Milijaona Randrianarivelojosia, Benjamin Ramarosandratana, Frédéric Ariey, Victor Mwapasa, Steven R Meshnick
Malar J. 2009; 8: 47. Published online 2009 March 16. doi: 10.1186/1475-2875-8-47
PMCID:
PMC2664821
Abstract Full Text PDF–430K
Plasmodium falciparum Na+/H+ Exchanger 1 Transporter Is Involved in Reduced Susceptibility to Quinine
Maud Henry, Sébastien Briolant, Agnès Zettor, Stéphane Pelleau, Meili Baragatti, Eric Baret, Joel Mosnier, Rémy Amalvict, Thierry Fusai, Christophe Rogier, Bruno Pradines
Antimicrob Agents Chemother. 2009 May; 53(5): 1926–1930. Published online 2009 March 9. doi: 10.1128/AAC.01243-08
PMCID:
PMC2681529
Abstract Full Text PDF–844K
Malarial parasite pathogenesis and drug targets
Paul D Roepe
F1000 Biol Rep. 2009; 1: 18. Published online 2009 February 24. doi: 10.3410/B1-18
PMCID:
PMC2920689
Abstract Full Text PDF–103K
The evolution of drug-resistant malaria
Christopher V. Plowe
Trans R Soc Trop Med Hyg. Author manuscript; available in PMC 2009 August 10.
Published in final edited form as: Trans R Soc Trop Med Hyg. 2009 April; 103(Suppl 1): S11–S14. Published online 2008 December 12. doi: 10.1016/j.trstmh.2008.11.002
PMCID:
PMC2723787
Abstract Full Text PDF–83K
Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependent
Carmony L. Hartwig, Andrew S. Rosenthal, John D' Angelo, Carol E. Griffin, Gary H. Posner, Roland A. Cooper
Biochem Pharmacol. Author manuscript; available in PMC 2010 February 1.
Published in final edited form as: Biochem Pharmacol. 2009 February 1; 77(3): 322–336. Published online 2008 October 19. doi: 10.1016/j.bcp.2008.10.015
PMCID:
PMC2659783
Abstract Full Text PDF–2.1M
Synthesis, Antimalarial Activity, and Intracellular Targets of MEFAS, a New Hybrid Compound Derived from Mefloquine and Artesunate
Fernando de Pilla Varotti, Ana Cristina C. Botelho, Anderson Assunção Andrade, Renata C. de Paula, Elaine M. S. Fagundes, Alessandra Valverde, Lúcia M. U. Mayer, Jorge Souza Mendonça, Marcus V. N. de Souza, Núbia Boechat, Antoniana Ursine Krettli
Antimicrob Agents Chemother. 2008 November; 52(11): 3868–3874. Published online 2008 August 18. doi: 10.1128/AAC.00510-08
PMCID:
PMC2573098
Abstract Full Text PDF–286K
World Antimalarial Resistance Network (WARN) IV: Clinical pharmacology
Karen I Barnes, Niklas Lindegardh, Olumide Ogundahunsi, Piero Olliaro, Christopher V Plowe, Milijaona Randrianarivelojosia, Grace O Gbotosho, William M Watkins, Carol H Sibley, Nicholas J White
Malar J. 2007; 6: 122. Published online 2007 September 6. doi: 10.1186/1475-2875-6-122
PMCID:
PMC2014777
Abstract Full Text PDF–271K
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