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Br J Cancer. 1991 Jun; 63(6): 963–966.
PMCID: PMC1972548

Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County.


Using age-adjusted incidence rates and proportional incidence ratios, the risks of prostate cancer and breast cancer in three racial/ethnic groups - Spanish-surnamed whites, other whites and Japanese - were studied in Los Angeles County native residents and compared with those in immigrants and representative 'homeland' populations. An algorithm based on social security numbers was developed and utilised to estimate age at immigration for non-US-born Los Angeles County cancer patients. For prostate cancer, the incidence rates in Los Angeles County were much higher than those in the homelands for each racial/ethnic group. However, prostate cancer rates of immigrants were similar to those of US-born patients in the Spanish-surnamed white and Japanese populations, regardless of age at immigration. For breast cancer, the incidence rates in Los Angeles County were also high compared with those in the homelands. However, the timing of immigration to the US was important in determining breast cancer risk. When social security numbers indicated that migration occurred later in life, rates for breast cancer were substantially lower than when migration occurred early, although they were still much higher than in the homeland populations. These findings suggest that environmental factors in early life rather than in later life are important in the etiology of breast cancer and that later life events can substantially impact the likelihood of developing clinically detectable prostate cancer.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Berg JW. Can nutrition explain the pattern of international epidemiology of hormone-dependent cancers? Cancer Res. 1975 Nov;35(11 Pt 2):3345–3350. [PubMed]
  • Block G, Matanoski GM, Seltser RS. A method for estimating year of birth using social security number. Am J Epidemiol. 1983 Sep;118(3):377–395. [PubMed]
  • Buell P. Changing incidence of breast cancer in Japanese-American women. J Natl Cancer Inst. 1973 Nov;51(5):1479–1483. [PubMed]
  • Goodwin PJ, Boyd NF. Critical appraisal of the evidence that dietary fat intake is related to breast cancer risk in humans. J Natl Cancer Inst. 1987 Sep;79(3):473–485. [PubMed]
  • Hill PB, Wynder EL. Effect of a vegetarian diet and dexamethasone on plasma prolactin, testosterone and dehydroepiandrosterone in men and women. Cancer Lett. 1979 Sep;7(5):273–282. [PubMed]
  • Hill P, Wynder E, Garbaczewski L, Garnes H, Walker AR, Helman P. Plasma hormones and lipids in men at different risk for coronary heart disease. Am J Clin Nutr. 1980 May;33(5):1010–1018. [PubMed]
  • Kato I, Tominaga S, Suzuki T. Factors related to late menopause and early menarche as risk factors for breast cancer. Jpn J Cancer Res. 1988 Feb;79(2):165–172. [PubMed]
  • Mack TM. Cancer surveillance program in Los Angeles County. Natl Cancer Inst Monogr. 1977 Dec;47:99–101. [PubMed]
  • Mack TM, Walker A, Mack W, Bernstein L. Cancer in Hispanics in Los Angeles County. Natl Cancer Inst Monogr. 1985 Dec;69:99–104. [PubMed]
  • MacMahon B, Cole P, Brown J. Etiology of human breast cancer: a review. J Natl Cancer Inst. 1973 Jan;50(1):21–42. [PubMed]
  • Ross R, Bernstein L, Judd H, Hanisch R, Pike M, Henderson B. Serum testosterone levels in healthy young black and white men. J Natl Cancer Inst. 1986 Jan;76(1):45–48. [PubMed]
  • Ross RK, Shimizu H, Paganini-Hill A, Honda G, Henderson BE. Case-control studies of prostate cancer in blacks and whites in southern California. J Natl Cancer Inst. 1987 May;78(5):869–874. [PubMed]
  • Shimizu H, Mack TM, Ross RK, Henderson BE. Cancer of the gastrointestinal tract among Japanese and white immigrants in Los Angeles County. J Natl Cancer Inst. 1987 Feb;78(2):223–228. [PubMed]
  • Yatani R, Shiraishi T, Nakakuki K, Kusano I, Takanari H, Hayashi T, Stemmermann GN. Trends in frequency of latent prostate carcinoma in Japan from 1965-1979 to 1982-1986. J Natl Cancer Inst. 1988 Jul 6;80(9):683–687. [PubMed]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK


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