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Can Med Assoc J. Jan 11, 1975; 112(1): 53–54.
PMCID: PMC1956027

Hepatitis B antigenemia among blood donors: the changing scene.


For the period May 1973 to August 1974 inclusive, the mean prevalence of hepatitis B antigenemia (HBsAg) in all Canadian provinces (per 100,000 population) was, for "first-time" donors, 242 and, for "repeat" donors, 77. A modification of counterimmunoelectrophoresis was used in all 16 regional transfusion centres. The findings confirm the previously noted high prevalence for the Province of Québec and the continuing relatively high prevalence for Canada. The prevalence of HBsAg among donors could be lessened by institution of the following measures: development of a more effective technique for the screening of hepatitis carriers, study of nonparenterally transmitted hepatitis, better reporting of post-transfusion hepatitis, and greater discrimination in prescribing blood and blood components.

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Selected References

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  • Moore BP, Meade D. Counter-immunoelectrophoresis for detection of hepatitis B antigen and antibody: a technique for large-scale use. Can J Public Health. 1972 Sep-Oct;63(5):453–459. [PubMed]
  • Moore BP, Meade D, Taylor PE, Kelen AE. An international proficiency survey for the detection of hepatitis B antigen and antibody in blood donations by counterimmunoelectrophoresis. Vox Sang. 1974 Feb;26(2):128–132. [PubMed]

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