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Journal List > Can Med Assoc J > v.98(6); Feb 10, 1968

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Can Med Assoc J. 1968 February 10; 98(6): 278–293.
PMCID: PMC1923817
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Predictive drug toxicity. Assessment of drug safety before human use.
E. M. Boyd
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • BOYD CE, BOYD EM, BROWN MD. Penicillin vomiting. Can Med Assoc J. 1960 Jan 23;82:195–197. [PubMed]
  • BOYD EM, BROWN MD, CASSELL WA. Delayed vomiting induced in dogs by intramuscular digoxin. J Pharm Pharmacol. 1959 Dec;11:742–746. [PubMed]
  • BOYD EM, JARZYLO S. Chronic atropinization and fibrocystic disease of the pancreas. Can Med Assoc J. 1960 Apr 16;82:821–824. [PubMed]
  • BOYD EM, JARZYLO S, BOYD CE, CASSELL WA. The chronic oral toxicity of spiramycin in dogs. Arch Int Pharmacodyn Ther. 1958 Jun 1;115(3):360–371. [PubMed]
  • Boyd EM, Lloyd GR. Minimal oral doses of benzylpenicillin producing signs of toxicity in albino rats. Arch Int Pharmacodyn Ther. 1965 Jul;156(1):172–179. [PubMed]
  • Boyd EM, Covert EL, Shanas MN. Death from bowel obstruction due to intragastrically administered kaolin. Ind Med Surg. 1965 Nov;34(11):874–880. [PubMed]
  • Boyd EM, Abel M. The acute toxicity of barium sulfate administered intragastrically. Can Med Assoc J. 1966 Apr 16;94(16):849–853. [PubMed]
  • BOYD EM, BOYD CE. Antihistaminics and apomorphine-induced vomiting. Can J Med Sci. 1953 Aug;31(4):320–325. [PubMed]
  • BOYD EM, PRICE-JONES MA. The comparative acute oral toxicity of spiramycin adipate in mice, rats, guinea pigs, and rabbits. Antibiot Chemother. 1960 May;10:273–284. [PubMed]
  • BOYD EM. The acute oral toxicity in guinea pigs of acetylsalicylic acid, phenacetin, and caffeine, alone and combined. Toxicol Appl Pharmacol. 1960 Jan;2:23–32. [PubMed]
  • BOYD CE, BOYD EM. The acute toxicity of atropine sulfate. Can Med Assoc J. 1961 Dec 2;85:1241–1244. [PubMed]
  • BOYD EM, BROUGHTON RJ, JAMES J. The acute oral toxicity of benzylpenicillin ammonium. Antibiot Chemother. 1959 Dec;9:739–743. [PubMed]
  • BOYD CE. The acute oral toxicity of benzylpenicillin potassium in the rabbit. Antibiot Chemother. 1960 Jun;10:376–384. [PubMed]
  • Peters JM, Boyd EM. The influence of sex and age in albino rats given a daily oral dose of caffeine at a high dose level. Can J Physiol Pharmacol. 1967 Mar;45(2):305–311. [PubMed]
  • Peters JM. Organ weights and water contents of fully grown female rats. Toxicol Appl Pharmacol. 1967 Jan;10(1):21–26. [PubMed]
  • Boyd EM, Godi I, Abel M. Acute oral toxicity of sucrose. Toxicol Appl Pharmacol. 1965 Jul;7(4):609–618. [PubMed]
  • Peters JM, Krijnen CJ, Boyd EM. Role of concepta in the production of hypertrophy and hydration of maternal body organs in the third week of pregnancy in albino rats. J Reprod Fertil. 1967 Oct;14(2):235–242. [PubMed]
  • BOYD EM, BERECZKY K, GODI I. THE ACUTE TOXICITY OF TANNIC ACID ADMINISTERED INTRAGASTRICALLY. Can Med Assoc J. 1965 Jun 19;92:1292–1297. [PubMed]
  • BAIRD JA, BOYD EM. Antazoline hydrochloride, tripelennamine hydrochloride and locomotor activity. J Pharm Pharmacol. 1954 Jun;6(6):398–402. [PubMed]
  • BOYD EM, SELBY MJ. The chronic oral toxicity of benzylpenicillin. Antibiot Chemother. 1962 Apr;12:249–262. [PubMed]
  • Boyd EM, Abel MM, Knight LM. The chronic oral toxicity of sodium chloride at the range of the LD-50(0.1l). Can J Physiol Pharmacol. 1966 Jan;44(1):157–172. [PubMed]
  • Singh J, Boyd EM. Thiopental anesthesia and tannic acid diagnostic enemas. Can Med Assoc J. 1966 Sep 10;95(11):558–562. [PubMed]
  • Peters JM, Boyd EM. Resistance to pentobarbital in rats fed a cachexigenic diet. Toxicol Appl Pharmacol. 1966 May;8(3):464–471. [PubMed]
  • Peters JM, Boyd EM. Organ weights and water levels of the rat following reduced food intake. J Nutr. 1966 Dec;90(4):354–360. [PubMed]
  • BOYD EM. ASCORBIC ACID AND BENZYLPENICILLIN TOXICITY. Clin Med (Northfield Il). 1963 Dec;70:2223–2229. [PubMed]
  • BOYD EM, MULROONEY DA, SARGEANT EJ. The toxicity of benzylpenicillin in animals on vitamin A deficient test diet, U.S.P. XIV. Can J Biochem Physiol. 1962 Dec;40:1685–1692. [PubMed]
  • BOYD EM, MULROONEY DA, PITMAN CA, ABEL M. BENZYLPENICILLIN TOXICITY IN ANIMALS ON A SYNTHETIC HIGH SUCROSE DIET. Can J Physiol Pharmacol. 1965 Jan;43:47–54. [PubMed]
  • Peters JM, Krijnen CJ. Organ weights and water contents of rats fed purified diets. Growth. 1966 Mar;30(1):99–107. [PubMed]
  • Boyd EM, Covert EL, Pitman CA. Benzylpenicillin toxicity in albino rats fed synthetic high sugar diets. Chemotherapy. 1966;11(6):320–330. [PubMed]
  • Peters JM. A separation of the direct toxic effects of dietary raw egg white powder from its action in producing biotin deficiency. Br J Nutr. 1967;21(4):801–809. [PubMed]
  • BOYD EM, SARGEANT EJ. The production of skin reactions to benzylpenicillin in animals on a biotin-deficient diet. J New Drugs. 1962 Sep–Oct;2:283–291. [PubMed]
  • Boyd EM, Peters JM, Krynen CJ. The acute oral toxicity of reconstituted spray-dried egg white. Ind Med Surg. 1966 Sep;35(9):782–787. [PubMed]
  • BOYD EM, SHANAS MN. The acute oral toxicity of potassium chloride. Arch Int Pharmacodyn Ther. 1961 Oct 1;133:275–283. [PubMed]
  • Boyd EM, Godi I. Acute oral toxicity of distilled water in albino rats. Ind Med Surg. 1967 Sep;36(9):609–613. [PubMed]
  • Coldwell BB, Boyd EM. The acute rectal toxicity of acetylsalicylic acid. Can J Physiol Pharmacol. 1966 Nov;44(6):909–918. [PubMed]
  • Boyd EM, Bereczky GM. Liver necrosis from paracetamol. Br J Pharmacol Chemother. 1966 Mar;26(3):606–614. [PubMed]
  • Boyd EM, Sheppard EP. Dose-response changes in organ weights and water contents following administration of toxic doses of paracetamol. Br J Pharmacol Chemother. 1966 Sep;27(3):497–505. [PubMed]
  • Peters JM. Caffeine-induced hemorrhagic automutilation. Arch Int Pharmacodyn Ther. 1967 Sep;169(1):139–146. [PubMed]
  • Singh J, Boyd EM. The acute toxicity of tannic acid in the tannic acid-barium sulfate radiodiagnostic enema. J Can Assoc Radiol. 1966 Sep;17(3):124–131. [PubMed]
  • Boyd EM, Singh J. Acute toxicity following rectal thiopental, phenobarbital and leptazol. Anesth Analg. 1967 Jul–Aug;46(4):395–400. [PubMed]
  • BOYD EM. A search for drugs with disulfiram like activity. Q J Stud Alcohol. 1960 Mar;21:23–25. [PubMed]
  • Uhlenhuth EH, Rickels K, Fisher S, Park LC, Lipman RS, Mock J. Drug, doctor's verbal attitude and clinic setting in the symptomatic response to pharmacotherapy. Psychopharmacologia. 1966;9(5):392–418. [PubMed]
  • BOYD EM, CASSELL WA. Agents affecting apomorphine-induced vomiting. J Pharmacol Exp Ther. 1957 Mar;119(3):390–394. [PubMed]
  • BOYD EM. The chronic subcutaneous toxicity of spiramycin adipate. Can Med Assoc J. 1958 May 1;78(9):671–674. [PubMed]
  • Boyd EM, Godi I, Krijnen CJ. The acute oral toxicity of a vasicin derivative. J New Drugs. 1966 Sep–Oct;6(5):269–277. [PubMed]
  • BOYD EM, KNIGHT LM. Postmortem shifts in the weight and water levels of body organs. Toxicol Appl Pharmacol. 1963 Jan;5:119–128. [PubMed]
  • BOYD EM, CRANDELL EM. The concentration of lipids and water in skeletal muscle of albino rats bearing Walker carcinoma 256. Cancer Res. 1956 Mar;16(3):198–203. [PubMed]
  • MILLS DW. Studies on the chronic oral toxicity of potassium penicilin G. Arch Int Pharmacodyn Ther. 1960 Apr 1;125:83–95. [PubMed]
  • BOYD EM, BOYD CE, CASSELL WA. The antemetic action of chlorpromazine hydrochloride. Can Med Assoc J. 1954 Mar;70(3):276–280. [PubMed]
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