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Am J Pathol. 1975 January; 78(1): 171–174.
PMCID: PMC1915035
Animal model of human disease. Pulmonary alveolar lipo-proteinosis. Animal model: Silica-induced pulmonary alveolar lipo-proteinosis.
A. G. Heppleston
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Selected References
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  • ROSEN SH, CASTLEMAN B, LIEBOW AA. Pulmonary alveolar proteinosis. N Engl J Med. 1958 Jun 5;258(23):1123–1142. [PubMed]
  • Heppleston AG. Atypical reaction to inhaled silica. Nature. 1967 Jan 14;213(5072):199–199. [PubMed]
  • Heppleston AG, Wright NA, Stewart JA. Experimental alveolar lipo-proteinosis following the inhalation of silica. J Pathol. 1970 Aug;101(4):293–307. [PubMed]
  • Heppleston AG, Young AE. Alveolar lipo-proteinosis: an ultrastructural comparison of the experimental and human forms. J Pathol. 1972 Jun;107(2):107–117. [PubMed]
  • Heppleston AG, Fletcher K, Wyatt I. Abnormalities of lung lipids following inhalation of quartz. Experientia. 1972 Aug 15;28(8):938–939. [PubMed]
  • Askin FB, Kuhn C. The cellular origin of pulmonary surfactant. Lab Invest. 1971 Sep;25(3):260–268. [PubMed]
  • Kuhn C, Györkey F, Levine BE, Ramirez-Rivera J. Pulmonary alveolar proteinosis. A study using enzyme histochemistry, electron microscopy, and surface tension measurement. Lab Invest. 1966 Feb;15(2):492–509. [PubMed]
  • Ramirez J, Harlan WR., Jr Pulmonary alveolar proteinosis. Nature and origin of alveolar lipid. Am J Med. 1968 Oct;45(4):502–512. [PubMed]
  • Buechner HA, Ansari A. Acute silico-proteinosis. A new pathologic variant of acute silicosis in sandblasters, characterized by histologic features resembling alveolar proteinosis. Dis Chest. 1969 Apr;55(4):274–278. [PubMed]
  • Hoffmann EO, Lamberty J, Pizzolato P, Coover J. The ultrastructure of acute silicosis. Arch Pathol. 1973 Aug;96(2):104–107. [PubMed]
  • Heppleston AG, Styles JA. Activity of a macrophage factor in collagen formation by silica. Nature. 1967 Apr 29;214(5087):521–522. [PubMed]
  • Burrell R, Anderson M. The induction of fibrogenesis by silica-treated alveolar macrophages. Environ Res. 1973 Dec;6(4):389–394. [PubMed]