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Journal List > Am J Hum Genet > v.59(5); Nov 1996

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Am J Hum Genet. 1996 November; 59(5): 983–989.
PMCID: PMC1914831
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The TDT and other family-based tests for linkage disequilibrium and association.
R. S. Spielman and W. J. Ewens
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • Cox NJ, Baker L, Spielman RS. Insulin-gene sharing in sib pairs with insulin-dependent diabetes mellitus: no evidence for linkage. Am J Hum Genet. 1988 Jan;42(1):167–172. [PubMed]
  • Curtis D, Sham PC. A note on the application of the transmission disequilibrium test when a parent is missing. Am J Hum Genet. 1995 Mar;56(3):811–812. [PubMed]
  • Duffy DL. Screening a 2 cM genetic map for allelic association: a simulated oligogenic trait. Genet Epidemiol. 1995;12(6):595–600. [PubMed]
  • Ewens WJ, Spielman RS. The transmission/disequilibrium test: history, subdivision, and admixture. Am J Hum Genet. 1995 Aug;57(2):455–464. [PubMed]
  • Falk CT, Rubinstein P. Haplotype relative risks: an easy reliable way to construct a proper control sample for risk calculations. Ann Hum Genet. 1987 Jul;51(Pt 3):227–233. [PubMed]
  • Field LL, Fothergill-Payne C, Bertrams J, Baur MP. HLA-DR effects in a large German IDDM dataset. Genet Epidemiol Suppl. 1986;1:323–328. [PubMed]
  • Harley JB, Moser KL, Neas BR. Logistic transmission modeling of simulated data. Genet Epidemiol. 1995;12(6):607–612. [PubMed]
  • Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet. 1995 Nov;11(3):241–247. [PubMed]
  • Lander ES, Schork NJ. Genetic dissection of complex traits. Science. 1994 Sep 30;265(5181):2037–2048. [PubMed]
  • Ott J. Statistical properties of the haplotype relative risk. Genet Epidemiol. 1989;6(1):127–130. [PubMed]
  • Parsian A, Todd RD, Devor EJ, O'Malley KL, Suarez BK, Reich T, Cloninger CR. Alcoholism and alleles of the human D2 dopamine receptor locus. Studies of association and linkage. Arch Gen Psychiatry. 1991 Jul;48(7):655–663. [PubMed]
  • Rice JP, Neuman RJ, Hoshaw SL, Daw EW, Gu C. TDT with covariates and genomic screens with mod scores: their behavior on simulated data. Genet Epidemiol. 1995;12(6):659–664. [PubMed]
  • Schaid DJ, Sommer SS. Comparison of statistics for candidate-gene association studies using cases and parents. Am J Hum Genet. 1994 Aug;55(2):402–409. [PubMed]
  • Sham PC, Curtis D. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann Hum Genet. 1995 Jul;59(Pt 3):323–336. [PubMed]
  • Spielman RS, Baur MP, Clerget-Darpoux F. Genetic analysis of IDDM: summary of GAW5 IDDM results. Genet Epidemiol. 1989;6(1):43–58. [PubMed]
  • Spielman RS, McGinnis RE, Ewens WJ. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet. 1993 Mar;52(3):506–516. [PubMed]
  • Terwilliger JD. A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more polymorphic marker loci. Am J Hum Genet. 1995 Mar;56(3):777–787. [PubMed]
  • Thomson G. Mapping disease genes: family-based association studies. Am J Hum Genet. 1995 Aug;57(2):487–498. [PubMed]
  • Thomson G, Robinson WP, Kuhner MK, Joe S, Klitz W. HLA and insulin gene associations with IDDM. Genet Epidemiol. 1989;6(1):155–160. [PubMed]
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