Ioannis Mitroulis, Konstantinos Kambas, Akrivi Chrysanthopoulou, Panagiotis Skendros, Eirini Apostolidou, Ioannis Kourtzelis, Georgios I. Drosos, Dimitrios T. Boumpas, Konstantinos Ritis

PLoS One. 2011; 6(12): e29318. Published online 2011 December 16. doi: 10.1371/journal.pone.0029318

PMCID:: PMC3241704

Abstract Full Text PDF–1.7M Supplementary Material

The inflammasome: in memory of Dr. Jurg Tschopp

M Dagenais, A Skeldon, M Saleh

Cell Death Differ. 2012 January; 19(1): 5–12. Published online 2011 November 11. doi: 10.1038/cdd.2011.159

PMCID:: PMC3252823

Free in PMC on 2013/01/01

An update on the pathology and clinical management of gouty arthritis

Emilio B. Gonzalez

Clin Rheumatol. 2012 January; 31(1): 13–21. Published online 2011 November 9. doi: 10.1007/s10067-011-1877-0

PMCID:: PMC3249158

Abstract Full Text PDF–270K

Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation

Darwin J Prockop, Joo Youn Oh

Mol Ther. 2012 January; 20(1): 14–20. Published online 2011 October 18. doi: 10.1038/mt.2011.211

PMCID:: PMC3255583

Free in PMC on 2013/01/01

The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

P Menu, J E Vince

Clin Exp Immunol. 2011 October; 166(1): 1–15. doi: 10.1111/j.1365-2249.2011.04440.x

PMCID:: PMC3193914

Free in PMC on 2012/10/01

Caspase-1 Activation of Interleukin-1β (IL-1β) and IL-18 Is Dispensable for Induction of Experimental Cerebral Malaria

Maximilian Kordes, Kai Matuschewski, Julius Clemence R. Hafalla

Infect Immun. 2011 September; 79(9): 3633–3641. doi: 10.1128/IAI.05459-11

PMCID:: PMC3165484

Abstract Full Text PDF–2.1M Supplementary Material

Sensing damage by the NLRP3 inflammasome

Jaklien C. Leemans, Suzanne L. Cassel, Fayyaz S. Sutterwala

Immunol Rev. Author manuscript; available in PMC 2012 September 1.

Published in final edited form as: Immunol Rev. 2011 September; 243(1): 152–162. doi: 10.1111/j.1600-065X.2011.01043.x

PMCID:: PMC3170135

Free in PMC on 2012/09/01

NLRP3 inflammasomes link inflammation and metabolic disease

Dominic De Nardo, Eicke Latz

Trends Immunol. Author manuscript; available in PMC 2012 August 1.

Published in final edited form as: Trends Immunol. 2011 August; 32(8): 373–379. Published online 2011 July 4. doi: 10.1016/j.it.2011.05.004

PMCID:: PMC3151541

Free in PMC on 2012/08/01

Autoinflammation: translating mechanism to therapy

Taylor A. Doherty, Susannah D. Brydges, Hal M. Hoffman

J Leukoc Biol. 2011 July; 90(1): 37–47. doi: 10.1189/jlb.1110616

PMCID:: PMC3219035

Free in PMC on 2012/07/01

Renal co-morbidity in patients with rheumatic diseases

Hans-Joachim Anders, Volker Vielhauer

Arthritis Res Ther. 2011; 13(3): 222. Published online 2011 June 29. doi: 10.1186/ar3256

PMCID:: PMC3218868

Abstract Full Text PDF–236K

Serum Amyloid A (SAA) Activates the NLRP3 Inflammasome and Promotes T_H17 Allergic Asthma in Mice

Jennifer L. Ather, Karina Ckless, Rebecca Martin, Kathryn L. Foley, Benjamin T. Suratt, Jonathan E. Boyson, Katherine A. Fitzgerald, Richard A. Flavell, Stephanie C. Eisenbarth, Matthew E. Poynter

J Immunol. Author manuscript; available in PMC 2012 January 1.

Published in final edited form as: J Immunol. 2011 July 1; 187(1): 64–73. Published online 2011 May 27. doi: 10.4049/jimmunol.1100500

PMCID:: PMC3119761

Abstract Full Text PDF–1.8M

Histone Deacetylase Inhibitors for Treating a Spectrum of Diseases Not Related to Cancer

Charles A Dinarello, Gianluca Fossati, Paolo Mascagni

Mol Med. 2011 May-Jun; 17(5-6): 333–352. Published online 2011 May 5. doi: 10.2119/molmed.2011.00116

PMCID:: PMC3105126

Abstract Full Text PDF–139K

The human condition – an immunological perspective

Ronald N. Germain, Pamela L. Schwartzberg

Nat Immunol. Author manuscript; available in PMC 2011 August 31.

Published in final edited form as: Nat Immunol. 2011 May; 12(5): 369–372. doi: 10.1038/ni0511-369

PMCID:: PMC3164551

Full Text PDF–278K

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

Charles A. Dinarello

Blood. 2011 April 7; 117(14): 3720–3732. Prepublished online 2011 February 8. doi: 10.1182/blood-2010-07-273417

PMCID:: PMC3083294

Abstract Full Text Supplementary Material

The role of the NLRP3 inflammasome in gout

Sarah R Kingsbury, Philip G Conaghan, Michael F McDermott

J Inflamm Res. 2011; 4: 39–49. Published online 2011 March 13. doi: 10.2147/JIR.S11330

PMCID:: PMC3218743

Abstract Full Text PDF–322K

Mouse granzyme K has pro-inflammatory potential

L T Joeckel, R Wallich, P Martin, D Sanchez-Martinez, F C Weber, S F Martin, C Borner, J Pardo, C Froelich, M M Simon

Cell Death Differ. 2011 July; 18(7): 1112–1119. Published online 2011 February 11. doi: 10.1038/cdd.2011.5

PMCID:: PMC3131959

Free in PMC on 2012/07/01

XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases

Alexander M Owyang, Hassan Issafras, John Corbin, Kiran Ahluwalia, Paul Larsen, Elizabeth Pongo, Masahisa Handa, Arnold H Horwitz, Marina K Roell, Mary Haak-Frendscho, Linda Masat

MAbs. 2011 Jan-Feb; 3(1): 49–60. Published online 2011 January 1. doi: 10.4161/mabs.3.1.13989

PMCID:: PMC3038011

Abstract Full Text PDF–9.5M

Blocking Interleukin-1β in Acute and Chronic Autoinflammatory Diseases

Charles A. Dinarello

J Intern Med. Author manuscript; available in PMC 2012 January 1.

Published in final edited form as: J Intern Med. 2011 January; 269(1): 16–28. doi: 10.1111/j.1365-2796.2010.02313.x

PMCID:: PMC3074355

Abstract Full Text PDF–712K

Inflammasomes and autoimmunity

Patrick J. Shaw, Michael F. McDermott, Thirumala-Devi Kanneganti

Trends Mol Med. Author manuscript; available in PMC 2012 February 1.

Published in final edited form as: Trends Mol Med. 2011 February; 17(2): 57–64. Published online 2010 December 14. doi: 10.1016/j.molmed.2010.11.001

PMCID:: PMC3057120

Abstract Full Text PDF–381K

Inflammasome Sensor Nlrp1b-Dependent Resistance to Anthrax Is Mediated by Caspase-1, IL-1 Signaling and Neutrophil Recruitment

Mahtab Moayeri, Devorah Crown, Zachary L. Newman, Shu Okugawa, Michael Eckhaus, Christophe Cataisson, Shihui Liu, Inka Sastalla, Stephen H. Leppla

PLoS Pathog. 2010 December; 6(12): e1001222. Published online 2010 December 9. doi: 10.1371/journal.ppat.1001222

PMCID:: PMC3000361

Abstract Full Text PDF–1.3M

New and improved strategies for the treatment of gout

Natalie Dubchak, Gerald F Falasca

Int J Nephrol Renovasc Dis. 2010; 3: 145–166. Published online 2010 November 24. doi: 10.2147/IJNRD.S6048

PMCID:: PMC3108771

Abstract Full Text PDF–290K

Cryopyrin-Associated Periodic Syndrome: An Update on Diagnosis and Treatment Response

Justin R. Yu, Kieron S. Leslie

Curr Allergy Asthma Rep. 2011 February; 11(1): 12–20. Published online 2010 November 23. doi: 10.1007/s11882-010-0160-9

PMCID:: PMC3020304

Abstract Full Text PDF–254K

Lack of the purinergic receptor P2X₇ results in resistance to contact hypersensitivity

Felix C. Weber, Philipp R. Esser, Tobias Müller, Jayanthi Ganesan, Patrizia Pellegatti, Markus M. Simon, Robert Zeiser, Marco Idzko, Thilo Jakob, Stefan F. Martin

J Exp Med. 2010 November 22; 207(12): 2609–2619. doi: 10.1084/jem.20092489

PMCID:: PMC2989767

Abstract Full Text PDF–1.8M Supplementary Material

Sterile inflammation: sensing and reacting to damage

Grace Y. Chen, Gabriel Nuñez

Nat Rev Immunol. Author manuscript; available in PMC 2011 December 1.

Published in final edited form as: Nat Rev Immunol. 2010 December; 10(12): 826–837. Published online 2010 November 19. doi: 10.1038/nri2873

PMCID:: PMC3114424

Abstract Full Text PDF–200K

Fatty acids engagement with TLR2 drive IL-1β production via ASC-caspase-1 pathway by urate crystals in gouty arthritis

Leo A.B. Joosten, Mihai G. Netea, Eleni Mylona, Marije I. Koenders, R. K. Subbarao Malireddi, Marije Oosting, Rinke Stienstra, Frank L. van de Veerdonk, Anton F. Stalenhoef, Evangelos J. Giamarellos-Bourboulis, Thirumala-Devi Kanneganti, Jos W.M. van der Meer

Arthritis Rheum. Author manuscript; available in PMC 2011 November 1.

Published in final edited form as: Arthritis Rheum. 2010 November; 62(11): 3237–3248. doi: 10.1002/art.27667