• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of aacPermissionsJournals.ASM.orgJournalAAC ArticleJournal InfoAuthorsReviewers
Antimicrob Agents Chemother. Jun 1992; 36(6): 1329–1331.
PMCID: PMC190341

Antimicrobial susceptibilities of a Corynebacterium CDC group I1 strain isolated from a patient with endocarditis.


We encountered a case of native valve endocarditis due to Corynebacterium CDC group I1 which was successfully controlled with antimicrobial agents alone. This organism and three other isolates of this group were susceptible to penicillin, vancomycin, and gentamicin. The combination of penicillin with subinhibitory concentrations of gentamicin resulted in a 1,000-fold decrease in CFU per milliliter at 24 h compared with penicillin alone. Augmentation of killing was noted also with vancomycin plus gentamicin but to a degree that did not meet strict criteria for bactericidal synergism.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (509K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Austin GE, Hill EO. Endocarditis due to Corynebacterium CDC group G2. J Infect Dis. 1983 Jun;147(6):1106–1106. [PubMed]
  • Eliakim R, Silkoff P, Lugassy G, Michel J. Corynebacterium xerosis endocarditis. Arch Intern Med. 1983 Oct;143(10):1995–1995. [PubMed]
  • Farrer W. Four-valve endocarditis caused by corynebacterium CDC group I1. South Med J. 1987 Jul;80(7):923–925. [PubMed]
  • Geraci JE, Forth RJ, Ellis FH., Jr Postoperative prosthetic valve bacterial endocarditis due to Corynebacterium xerosis. Mayo Clin Proc. 1967 Nov;42(11):736–743. [PubMed]
  • Gerry JL, Greenough WB., 3rd Diphtheroid endocarditis. Report of nine cases and review of the literature. Johns Hopkins Med J. 1976 Aug;139(2):61–68. [PubMed]
  • Johnson WD, Cobbs CG, Arditi LI, Kaye D. Diphtheroid endocarditis after insertion of a prosthetic heart valve. Report of two cases. JAMA. 1968 Mar 11;203(11):919–921. [PubMed]
  • Jootar P, Gherunpong V, Saitanu K. Corynebacterium pyogenes endocarditis. Report of a case with necropsy and review of the literature. J Med Assoc Thai. 1978 Oct;61(10):596–601. [PubMed]
  • Lipsky BA, Goldberger AC, Tompkins LS, Plorde JJ. Infections caused by nondiphtheria corynebacteria. Rev Infect Dis. 1982 Nov-Dec;4(6):1220–1235. [PubMed]
  • Love JW, Medina D, Anderson S, Braniff B. Infective endocarditis due to Corynebacterium diphtheriae: report of a case and review of the literature. Johns Hopkins Med J. 1981 Jan;148(1):41–42. [PubMed]
  • Murray BE, Karchmer AW, Moellering RC., Jr Diphtheroid prosthetic valve endocarditis. A study of clinical features and infecting organisms. Am J Med. 1980 Dec;69(6):838–848. [PubMed]
  • Pearson RD, Steigbigel RT, Davis HT, Chapman SW. Method of reliable determination of minimal lethal antibiotic concentrations. Antimicrob Agents Chemother. 1980 Nov;18(5):699–708. [PMC free article] [PubMed]
  • Vale JA, Scott GW. Corynebacterium bovis as a cause of human disease. Lancet. 1977 Oct 1;2(8040):682–684. [PubMed]
  • Wilson WR, Danielson GK, Giuliani ER, Geraci JE. Prosthetic valve endocarditis. Mayo Clin Proc. 1982 Mar;57(3):155–161. [PubMed]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)


Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...