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Antimicrob Agents Chemother. 1992 May; 36(5): 1144–1146.
PMCID: PMC188853
Ofloxacin versus doxycycline for treatment of cervical infection with Chlamydia trachomatis.
T M Hooton, B E Batteiger, F N Judson, S L Spruance, and W E Stamm
Department of Medicine, University of Washington School of Medicine, Harborview Medical Center, Seattle 98104.
Abstract
Women with culture-proven Chlamydia trachomatis cervical infection were randomized to receive either ofloxacin (300 mg) or doxycycline (100 mg), orally twice daily for 7 days. All 56 had negative cultures 5 to 9 days after treatment. Four weeks after treatment, 26 (93%) of 28 ofloxacin-treated patients and all 22 doxycycline-treated patients were cured. We conclude that 300 mg of ofloxacin given twice daily for 7 days provides effective therapy for chlamydial infection of the cervix.
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Selected References
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