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Am J Pathol. Mar 1986; 122(3): 562–572.
PMCID: PMC1888214

A primary lymph node malignancy with features suggestive of dendritic reticulum cell differentiation. A report of 4 cases.

Abstract

Four cases are described of a nonlymphomatous primary lymph node malignancy characterized by the proliferation of oval and spindle cells, occasionally multinucleated, and arranged in a nesting, swirling, and storiform pattern. The combination of light-microscopic, ultrastructural, and immunohistochemical features suggests that these tumors might be derived from dendritic reticulum cells.

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Selected References

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  • Wood GS, Link M, Warnke RA, Dilley J, Levy R. Pan-leukocyte monoclonal antibody L3B12. Characterization and application to research and diagnostic problems. Am J Clin Pathol. 1984 Feb;81(2):176–183. [PubMed]
  • Naiem M, Gerdes J, Abdulaziz Z, Stein H, Mason DY. Production of a monoclonal antibody reactive with human dendritic reticulum cells and its use in the immunohistological analysis of lymphoid tissue. J Clin Pathol. 1983 Feb;36(2):167–175. [PMC free article] [PubMed]
  • Kjeldsberg CR, Kim H. Polykaryocytes resembling Warthin-Finkeldey giant cells in reactive and neoplastic lymphoid disorders. Hum Pathol. 1981 Mar;12(3):267–272. [PubMed]
  • Stein H, Gerdes J, Mason DY. The normal and malignant germinal centre. Clin Haematol. 1982 Oct;11(3):531–559. [PubMed]
  • van der Valk P, van der Loo EM, Jansen J, Daha MR, Meijer CJ. Analysis of lymphoid and dendritic cells in human lymph node, tonsil and spleen. A study using monoclonal and heterologous antibodies. Virchows Arch B Cell Pathol Incl Mol Pathol. 1984;45(2):169–185. [PubMed]
  • Wood GS, Turner RR, Shiurba RA, Eng L, Warnke RA. Human dendritic cells and macrophages. In situ immunophenotypic definition of subsets that exhibit specific morphologic and microenvironmental characteristics. Am J Pathol. 1985 Apr;119(1):73–82. [PMC free article] [PubMed]
  • Groscurth P. Nicht-lymphatische Zellen in der Lymphknotenrinde der Maus. I. Morphologie und Verteilung der interdigitierenden Zellen und der dendritischen Retikulumzellen im mesenterialen Lymphknoten der adulten ICR Maus. Pathol Res Pract. 1980 Nov;169(3-4):212–234. [PubMed]
  • Heinen E, Lilet-Leclercq C, Mason DY, Stein H, Boniver J, Radoux D, Kinet-Denoël C, Simar LJ. Isolation of follicular dendritic cells from human tonsils and adenoids. II. Immunocytochemical characterization. Eur J Immunol. 1984 Mar;14(3):267–273. [PubMed]
  • Radoux D, Heinen E, Kinet-Denoël C, Tihange E, Simar L. Precise localization of antigens on follicular dendritic cells. Cell Tissue Res. 1984;235(2):267–274. [PubMed]
  • Parwaresch MR, Radzun HJ, Hansmann ML, Peters KP. Monoclonal antibody Ki-M4 specifically recognizes human dendritic reticulum cells (follicular dendritic cells) and their possible precursor in blood. Blood. 1983 Sep;62(3):585–590. [PubMed]
  • Hoefsmit EC, Duijvestijn AM, Kamperdijk EW. Relation between langerhans cells, veiled cells, and interdigitating cells. Immunobiology. 1982 Apr;161(3-4):255–265. [PubMed]
  • Rausch E, Kaiserling E, Goos M. Langerhans cells and interdigitating reticulum cells in the thymus-dependent region in human dermatopathic lymphadenitis. Virchows Arch B Cell Pathol. 1977 Nov 21;25(4):327–343. [PubMed]
  • Gerdes J, Stein H, Mason DY, Ziegler A. Human dendritic reticulum cells of lymphoid follicles: their antigenic profile and their identification as multinucleated giant cells. Virchows Arch B Cell Pathol Incl Mol Pathol. 1983;42(2):161–172. [PubMed]
  • Van der Valk P, Ruiter DJ, Den Ottolander GJ, Te Velde J, Spaander PJ, Meijer CJ. Dendritic reticulum cell sarcoma? Four cases of a lymphoma probably derived from dendritic reticulum cells of the follicular compartment. Histopathology. 1982 May;6(3):269–287. [PubMed]
  • Feltkamp CA, van Heerde P, Feltkamp-Vroom TM, Koudstaal J. A malignant tumor arising from interdigitating cells; light microscopical, ultrastructural, immuno-and enzyme-histochemical characteristics. Virchows Arch A Pathol Anat Histol. 1981;393(2):183–192. [PubMed]
  • Turner RR, Wood GS, Beckstead JH, Colby TV, Horning SJ, Warnke RA. Histiocytic malignancies. Morphologic, immunologic, and enzymatic heterogeneity. Am J Surg Pathol. 1984 Jul;8(7):485–500. [PubMed]

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