Figure 1
Trigone mucosa (A) with suprabasal immunostaining using the L1 antigen (B; A, H&E ×200; B, Mac387 monoclonal antibody ×200). Squamous differentiation (SqD) in urothelial carcinoma showing extensive corneous pearls (C), early corneous pearl formation with diskeratosis (D), koilocytotic appearance (E), intercellular bridges (F), clear cell features (G) and intracytoplasmic lumina (H; A, H&E ×100; B, C, D, H&E ×200; G, H&E ×100; H, H&E ×200). Diffuse immunostaining of SqD using the L1 antigen in large nests (I), small nests (J), individual cells (K) and intracytoplasmic lumina (L) (I ×100; J, K, L ×200; Mac387 monoclonal antibody.
Trigone mucosa (A) with suprabasal immunostaining using the L1 antigen (B; A, H&E ×200; B, Mac387 monoclonal antibody ×200). Squamous differentiation (SqD) in urothelial carcinoma showing extensive corneous pearls (C), early corneous pearl formation with diskeratosis (D), koilocytotic appearance (E), intercellular bridges (F), clear cell features (G) and intracytoplasmic lumina (H; A, H&E ×100; B, C, D, H&E ×200; G, H&E ×100; H, H&E ×200). Diffuse immunostaining of SqD using the L1 antigen in large nests (I), small nests (J), individual cells (K) and intracytoplasmic lumina (L) (I ×100; J, K, L ×200; Mac387 monoclonal antibody.