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Figure 4.

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Population structure in European individuals. A, PCoA based on average interindividual ASD across 9,114 SNPs. PC1, 2, 3, and 4 (fig. 5) explain 2.05%, 1.7%, 1.6%, and 1.5%, respectively, of the variation and were highly significant by SKT and ANOVA testing (see table 2). B, Bayesian clustering analysis using STRUCTURE and the same markers and European individuals. Each individual is represented as a vertical line divided into K colored segments, where K is the prespecified number of populations into which the data are to be divided. The clusteredness (measured by G)—the extent to which individuals belong to a single cluster rather than a combination of clusters30—is also given alongside each K value. See the legend of figure 1 for further details of STRUCTURE runs and conditions.

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