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Can Med Assoc J. 1961 September 9; 85(11): 631–637.
PMCID: PMC1848287
Spironolactone (Aldactone) Therapy for Ascites due to Cirrhosis of the Liver *
Charles H. Lockwood
*From the Clinical Investigation Unit, Westminster Hospital, London, Ontario; Department of Veterans Affairs, Canada.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • ONEN KH. Renal haemodynamics in hepatic cirrhosis. Lancet. 1960 Jan 23;1(7117):203–204. [PubMed]
  • GENEST J. Angiotensin, aldosterone and human arterial hypertension. Can Med Assoc J. 1961 Feb 25;84:403–419. [PubMed]
  • Biron P, Koiw E, Nowaczynski W, Brouillet J, Genest J. THE EFFECTS OF INTRAVENOUS INFUSIONS OF VALINE-5 ANGIOTENSIN II AND OTHER PRESSOR AGENTS ON URINARY ELECTROLYTES AND CORTICOSTEROIDS, INCLUDING ALDOSTERONE. J Clin Invest. 1961 Feb;40(2):338–347. [PubMed]
  • READ AE, LAIDLAW J, HASLAM RM, SHERLOCK S. Neuropsychiatric complications following chlorothiazide therapy in patients with hepatic cirrhosis: possible relation to hypokalaemia. Clin Sci. 1959 Aug;18:409–423. [PubMed]
  • SHALDON S, McLAREN JR, SHERLOCK S. Resistant ascites treated by combined diuretic therapy (spironolactone, mannitol, and chlorothiazide). Lancet. 1960 Mar 19;1(7125):609–613. [PubMed]
  • HENLEY KS, STREETEN DH, POLLARD HM. Hyperaldo-steronism in liver disease. The treatment of refractory ascites by adrenalectomy and by the administration of spirolactones. Gastroenterology. 1960 May;38:681–689. [PubMed]
  • FARRELLY RO, HOWIE RN, NORTH JD. Use of spironolactone and hydrochlorothiazide in treatment of oedema. Br Med J. 1960 Jul 30;2(5195):339–343. [PubMed]
  • GABUZDA GJ, Jr, DAVIDSON CS. Protein metabolism in patients with cirrhosis of the liver. Ann N Y Acad Sci. 1954 May 10;57(6):776–785. [PubMed]
  • TYOR MP, SIEKER HO. Biochemical, blood gas and peripheral circulatory alterations in hepatic coma. Am J Med. 1959 Jul;27(1):50–59. [PubMed]
  • SHERLOCK S. Pathogenesis and management of hepatic coma. Am J Med. 1958 May;24(5):805–813. [PubMed]
  • PITTS RF. Some reflections on mechanisms of action of diuretics. Am J Med. 1958 May;24(5):745–763. [PubMed]