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Can Med Assoc J. 1956 January 15; 74(2): 149–152.
PMCID: PMC1826442
Severe Hæmolytic Reaction Following the Intravenous Administration of Emulsified Vitamin K1 (Mephyton) *
R. E. Beamish and V. Marie Storrie
*From the Department of Medicine, University of Manitoba, and the Cardiac Department, Manitoba Clinic.
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Selected References
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  • DOUGLAS AS, BROWN A. Effect of vitamin K preparations on hypoprothrombinaemia induced by dicoumarol and tromexan. Br Med J. 1952 Feb 23;1(4755):412–415. [PubMed]
  • MILLER R, HARVEY WP, FINCH CA. Antagonism of dicumarol by vitamin K preparations. N Engl J Med. 1950 Feb 9;242(6):211–215. [PubMed]
  • STRAGNELL R, WARE AG. Mephyton (emulsified vitamin K1) in the treatment of excessive therapeutic hypoprothrombinemia. Med Clin North Am. 1954 Mar;11:413–417. [PubMed]
  • GAMBLE JR, DENNIS EW, COON WW, HODGSON P, WILLS PW, MACRIS JA, DUFF IF. Clinical comparison of vitamin K1 and water-soluble vitamin K. AMA Arch Intern Med. 1955 Jan;95(1):52–58. [PubMed]
  • GUTTAS CG, MOLONEY WC, SISE HS. Studies on the anticoagulant phenylindanedione. I. The effect of emulsified vitamin K1 on phenylindanedione-induced hypoprothrombinemia. Blood. 1953 Mar;8(3):276–281. [PubMed]