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Antimicrob Agents Chemother. 1986 April; 29(4): 713–715. | PMCID: PMC180474 |
In vitro activity of clavulanic acid, amoxicillin, and ticarcillin against Chlamydia trachomatis. W R Bowie Abstract In vitro, growth of Chlamydia trachomatis was not entirely eliminated by 960 micrograms of ticarcillin per ml, 64 micrograms of amoxicillin per ml, 32 micrograms of clavulanic acid per ml, a combination of ticarcillin (480 micrograms/ml) and clavulanic acid (32 micrograms/ml), and a combination of amoxicillin (32 micrograms/ml) and clavulanic acid (8 micrograms/ml). However, a greater than or equal to 99% decrease in the number of inclusions was obtained at concentrations readily attainable in serum. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (457K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. These references are in PubMed. This may not be the complete list of references from this article. - Becker Y, Asher Y. Synthesis of trachoma agent proteins in emetine-treated cells. J Bacteriol. 1972 Mar;109(3):966–970. [PubMed]
- Bowie WR. Lack of in vitro activity of cefoxitin, cefamandole, cefuroxime, and piperacillin against Chlamydia trachomatis. Antimicrob Agents Chemother. 1982 Feb;21(2):339–340. [PubMed]
- Bowie WR, Alexander ER, Holmes KK. Eradication of Chlamydia trachomatis from the urethras of men with nongonococcal urethritis by treatment with amoxicillin. Sex Transm Dis. 1981 Apr–Jun;8(2):79–81. [PubMed]
- Bowie WR, Lee CK, Alexander ER. Prediction of efficacy of antimicrobial agents in treatment of infections due to Chlamydia trachomatis. J Infect Dis. 1978 Nov;138(5):655–659. [PubMed]
- Bowie WR, Manzon LM, Borrie-Hume CJ, Fawcett A, Jones HD. Efficacy of treatment regimens for lower urogenital Chlamydia trachomatis infection in women. Am J Obstet Gynecol. 1982 Jan 15;142(2):125–129. [PubMed]
- Brogden RN, Carmine A, Heel RC, Morley PA, Speight TM, Avery GS. Amoxycillin/clavulanic acid: a review of its antibacterial activity, pharmacokinetics and therapeutic use. Drugs. 1981 Nov;22(5):337–362. [PubMed]
- Hammerschlag MR, Gleyzer A. In vitro activity of a group of broad-spectrum cephalosporins and other beta-lactam antibiotics against Chlamydia trachomatis. Antimicrob Agents Chemother. 1983 Mar;23(3):493–494. [PubMed]
- Holmes KK, Eschenbach DA, Knapp JS. Salpingitis: overview of etiology and epidemiology. Am J Obstet Gynecol. 1980 Dec 1;138(7 Pt 2):893–900. [PubMed]
- Johannisson G, Sernryd A, Lycke E. Susceptibility of Chlamydia trachomatis to antibiotics in vitro and in vivo. Sex Transm Dis. 1979 Apr–Jun;6(2):50–57. [PubMed]
- Kramer MJ, Gordon Francis B. Ultrastructural Analysis of the Effects of Penicillin and Chlortetracycline on the Development of a Genital Tract Chlamydia. Infect Immun. 1971 Feb;3(2):333–341. [PubMed]
- Kuo CC, Wang SP, Grayston JT. Antimicrobial activity of several antibiotics and a sulfonamide against Chlamydia trachomatis organisms in cell culture. Antimicrob Agents Chemother. 1977 Jul;12(1):80–83. [PubMed]
- Lee CK, Bowie WR, Alexander ER. In vitro assays of the efficacy of antimicrobial agents in controlling Chlamydia trachomatis propagation. Antimicrob Agents Chemother. 1978 Mar;13(3):441–445. [PubMed]
- Ridgway GL, Owen JM, Oriel JD. The antimicrobial susceptibility of Chlamydia trachomatis in cell culture. Br J Vener Dis. 1978 Apr;54(2):103–106. [PubMed]
- Stamm WE, Wagner KF, Amsel R, Alexander ER, Turck M, Counts GW, Holmes KK. Causes of the acute urethral syndrome in women. N Engl J Med. 1980 Aug 21;303(8):409–415. [PubMed]
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