Warning:
The NCBI web site requires JavaScript to function.
more...
Resources
All Resources
Chemicals & Bioassays
BioSystems
PubChem BioAssay
PubChem Compound
PubChem Structure Search
PubChem Substance
All Chemicals & Bioassays Resources...
DNA & RNA
BLAST (Basic Local Alignment Search Tool)
BLAST (Stand-alone)
E-Utilities
GenBank
GenBank: BankIt
GenBank: Sequin
GenBank: tbl2asn
Genome Workbench
Influenza Virus
Nucleotide Database
PopSet
Primer-BLAST
ProSplign
Reference Sequence (RefSeq)
RefSeqGene
Sequence Read Archive (SRA)
Splign
Trace Archive
UniGene
UniSTS
All DNA & RNA Resources...
Data & Software
BLAST (Basic Local Alignment Search Tool)
BLAST (Stand-alone)
Cn3D
Conserved Domain Search Service (CD Search)
E-Utilities
GenBank: BankIt
GenBank: Sequin
GenBank: tbl2asn
Genome ProtMap
Genome Workbench
Primer-BLAST
ProSplign
PubChem Structure Search
SNP Submission Tool
Splign
Vector Alignment Search Tool (VAST)
All Data & Software Resources...
Domains & Structures
BioSystems
Cn3D
Conserved Domain Database (CDD)
Conserved Domain Search Service (CD Search)
Structure (Molecular Modeling Database)
Vector Alignment Search Tool (VAST)
All Domains & Structures Resources...
Genes & Expression
BioSystems
Database of Genotypes and Phenotypes (dbGaP)
E-Utilities
Gene
Gene Expression Omnibus (GEO) Database
Gene Expression Omnibus (GEO) Datasets
Gene Expression Omnibus (GEO) Profiles
Genome Workbench
HomoloGene
Map Viewer
Online Mendelian Inheritance in Man (OMIM)
RefSeqGene
UniGene
All Genes & Expression Resources...
Genetics & Medicine
Bookshelf
Database of Genotypes and Phenotypes (dbGaP)
Genetic Testing Registry
Influenza Virus
Map Viewer
Online Mendelian Inheritance in Man (OMIM)
PubMed
PubMed Central (PMC)
PubMed Clinical Queries
RefSeqGene
All Genetics & Medicine Resources...
Genomes & Maps
Database of Genomic Structural Variation (dbVar)
GenBank: tbl2asn
Genome
Genome Project
Genome ProtMap
Genome Workbench
Influenza Virus
Map Viewer
Nucleotide Database
PopSet
ProSplign
Sequence Read Archive (SRA)
Splign
Trace Archive
UniSTS
All Genomes & Maps Resources...
Homology
BLAST (Basic Local Alignment Search Tool)
BLAST (Stand-alone)
BLAST Link (BLink)
Conserved Domain Database (CDD)
Conserved Domain Search Service (CD Search)
Genome ProtMap
HomoloGene
Protein Clusters
All Homology Resources...
Literature
Bookshelf
E-Utilities
Journals in NCBI Databases
MeSH Database
NCBI Handbook
NCBI Help Manual
NCBI News
PubMed
PubMed Central (PMC)
PubMed Clinical Queries
All Literature Resources...
Proteins
BioSystems
BLAST (Basic Local Alignment Search Tool)
BLAST (Stand-alone)
BLAST Link (BLink)
Conserved Domain Database (CDD)
Conserved Domain Search Service (CD Search)
E-Utilities
ProSplign
Protein Clusters
Protein Database
Reference Sequence (RefSeq)
All Proteins Resources...
Sequence Analysis
BLAST (Basic Local Alignment Search Tool)
BLAST (Stand-alone)
BLAST Link (BLink)
Conserved Domain Search Service (CD Search)
Genome ProtMap
Genome Workbench
Influenza Virus
Primer-BLAST
ProSplign
Splign
All Sequence Analysis Resources...
Taxonomy
Taxonomy
Taxonomy Browser
Taxonomy Common Tree
All Taxonomy Resources...
Training & Tutorials
NCBI Education Page
NCBI Handbook
NCBI Help Manual
NCBI News
Science Primer
All Training & Tutorials Resources...
Variation
Database of Genomic Structural Variation (dbVar)
Database of Genotypes and Phenotypes (dbGaP)
Database of Single Nucleotide Polymorphisms (dbSNP)
SNP Submission Tool
All Variation Resources...
How To
All How To
Chemicals & Bioassays
DNA & RNA
Data & Software
Domains & Structures
Genes & Expression
Genetics & Medicine
Genomes & Maps
Homology
Literature
Proteins
Sequence Analysis
Taxonomy
Training & Tutorials
Variation
Skip to main content
Skip to navigation
About NCBI Accesskeys
My NCBI
Sign In
Sign Out
PMC
US National Library of Medicine
National Institutes of Health
Search term
Search database
All Databases
PubMed
Protein
Nucleotide
GSS
EST
Structure
Genome
BioProject
BioSample
BioSystems
Books
Conserved Domains
Clone
dbGaP
dbVar
Epigenomics
Gene
GEO DataSets
GEO Profiles
HomoloGene
MeSH
NCBI Web Site
NLM Catalog
OMIA
OMIM
PMC
PopSet
Probe
Protein Clusters
PubChem BioAssay
PubChem Compound
PubChem Substance
PubMed Health
SNP
SRA
Taxonomy
ToolKit
ToolKitAll
UniGene
UniSTS
Search
Limits
Advanced
Journal list
Help
Journal List
>
Cited by
Combinatorial RNA interference in
Caenorhabditis elegans
reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution
Julia Tischler, Ben Lehner, Nansheng Chen, Andrew G Fraser
Genome Biol.
2006;
7(8): R69.
Published online 2006 August 2.
doi: 10.1186/gb-2006-7-8-r69
PMCID:
PMC1779603
Abstract
Full Text
PDF–471K
Supplementary Material
Is Cited by the Following 14 Articles in this Archive:
Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi
Elin Axelsson, Thomas Sandmann, Thomas Horn, Michael Boutros, Wolfgang Huber , Bernd Fischer
BMC Bioinformatics.
2011;
12: 342.
Published online 2011 August 17.
doi: 10.1186/1471-2105-12-342
PMCID:
PMC3230910
Abstract
Full Text
PDF–580K
Supplementary Material
The two actin-interacting protein 1 genes have overlapping and essential function for embryonic development in
Caenorhabditis elegans
Shoichiro Ono, Kazumi Nomura, Sadae Hitosugi, Domena K. Tu, Jocelyn A. Lee, David L. Baillie, Kanako Ono
Mol Biol Cell.
2011 July 1;
22(13): 2258–2269.
doi: 10.1091/mbc.E10-12-0934
PMCID:
PMC3128528
Abstract
Full Text
PDF–3.2M
Supplementary Material
Maintenance of duplicate genes and their functional redundancy by reduced expression
Wenfeng Qian, Ben-Yang Liao, Andrew Y.-F. Chang, Jianzhi Zhang
Trends Genet.
Author manuscript; available in PMC 2011 October 1.
Published in final edited form as:
Trends Genet.
2010 October;
26
(10)
: 425–430.
Published online 2010 August 12.
doi: 10.1016/j.tig.2010.07.002
PMCID:
PMC2942974
Abstract
Full Text
PDF–330K
Supplementary Material
Synthetic Lethal Genetic Interactions That Decrease Somatic Cell Proliferation in
Caenorhabditis elegans
Identify the Alternative RFC
CTF18
as a Candidate Cancer Drug Target
Jessica McLellan, Nigel O'Neil, Sanja Tarailo, Jan Stoepel, Jennifer Bryan, Ann Rose, Philip Hieter
Mol Biol Cell.
2009 December 15;
20(24): 5306–5313.
doi: 10.1091/mbc.E09-08-0699
PMCID:
PMC2793303
Abstract
Full Text
PDF–1.0M
Supplementary Material
Pharmacogenetic Analysis Reveals a Post-Developmental Role for Rac GTPases in
Caenorhabditis elegans
GABAergic Neurotransmission
Cody J. Locke, Bwarenaba B. Kautu, Kalen P. Berry, S. Kyle Lee, Kim A. Caldwell, Guy A. Caldwell
Genetics.
2009 December;
183(4): 1357–1372.
doi: 10.1534/genetics.109.106880
PMCID:
PMC2784297
Abstract
Full Text
PDF–2.8M
Evolutionary Persistence of Functional Compensation by Duplicate Genes in
Arabidopsis
Kousuke Hanada, Takashi Kuromori, Fumiyoshi Myouga, Tetsuro Toyoda, Wen-Hsiung Li, Kazuo Shinozaki
Genome Biol Evol.
2009;
1: 409–414.
Published online 2009 October 29.
doi: 10.1093/gbe/evp043
PMCID:
PMC2817435
Abstract
Full Text
PDF–281K
Supplementary Material
Buffering by gene duplicates: an analysis of molecular correlates and evolutionary conservation
Kevin Hannay, Edward M Marcotte, Christine Vogel
BMC Genomics.
2008;
9: 609.
Published online 2008 December 16.
doi: 10.1186/1471-2164-9-609
PMCID:
PMC2627895
Abstract
Full Text
PDF–1.7M
Supplementary Material
ced-4
and proto-oncogene
tfg-1
antagonistically regulate cell size and apoptosis in
C. elegans
Ling Chen, Tom McCloskey, Pradeep M. Joshi, Joel H. Rothman
Curr Biol.
Author manuscript; available in PMC 2011 July 25.
Published in final edited form as:
Curr Biol.
2008 July 22;
18
(14)
: 1025–1033.
doi: 10.1016/j.cub.2008.06.065
PMCID:
PMC3142714
Abstract
Full Text
PDF–1.6M
Supplementary Material
Homoplasy in genome-wide analysis of rare amino acid replacements: the molecular-evolutionary basis for Vavilov's law of homologous series
Igor B Rogozin, Karen Thomson, Miklós Csürös, Liran Carmel, Eugene V Koonin
Biol Direct.
2008;
3: 7.
Published online 2008 March 17.
doi: 10.1186/1745-6150-3-7
PMCID:
PMC2292158
Abstract
Full Text
PDF–890K
Supplementary Material
A
Caenorhabditis elegans
genetic-interaction map wiggles into view
Kristin C Gunsalus
J Biol.
2008;
7(3): 8.
Published online 2008 March 7.
doi: 10.1186/jbiol70
PMCID:
PMC2323036
Abstract
Full Text
PDF–639K
Preferential protection of protein interaction network hubs in yeast: Evolved functionality of genetic redundancy
Ran Kafri, Orna Dahan, Jonathan Levy, Yitzhak Pilpel
Proc Natl Acad Sci U S A.
2008 January 29;
105(4): 1243–1248.
Published online 2008 January 23.
doi: 10.1073/pnas.0711043105
PMCID:
PMC2234123
Abstract
Full Text
PDF–1.1M
Supplementary Material
Functional redundancy of worm spliceosomal proteins U1A and U2B″
Tassa Saldi, Carol Wilusz, Margaret MacMorris, Thomas Blumenthal
Proc Natl Acad Sci U S A.
2007 June 5;
104(23): 9753–9757.
Published online 2007 May 29.
doi: 10.1073/pnas.0701720104
PMCID:
PMC1887542
Abstract
Full Text
PDF–550K
Comparative analysis indicates regulatory neofunctionalization of yeast duplicates
Itay Tirosh, Naama Barkai
Genome Biol.
2007;
8(4): R50.
Published online 2007 April 5.
doi: 10.1186/gb-2007-8-4-r50
PMCID:
PMC1895995
Abstract
Full Text
PDF–500K
Supplementary Material
Accurate, precise modeling of cell proliferation kinetics from time-lapse imaging and automated image analysis of agar yeast culture arrays
Najaf A Shah, Richard J Laws, Bradley Wardman, Lue Ping Zhao, John L Hartman, IV
BMC Syst Biol.
2007;
1: 3.
Published online 2007 January 8.
doi: 10.1186/1752-0509-1-3
PMCID:
PMC1847469
Abstract
Full Text
PDF–1.1M
Supplementary Material
You are here:
NCBI
>
Literature
> PubMed Central (PMC)
Write to the Help Desk