• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of annrheumdAnnals of the Rheumatic DiseasesCurrent TOCInstructions for authors
Ann Rheum Dis. Nov 2005; 64(11): 1539–1541.
Published online Aug 17, 2005. doi:  10.1136/ard.2005.039263
PMCID: PMC1755271

Is progressive osteoarthritis an atheromatous vascular disease?

Full Text

The Full Text of this article is available as a PDF (57K).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Felson DT, Lawrence RC, Dieppe PA, Hirsch R, Helmick CG, Jordan JM, Kington RS, Lane NE, Nevitt MC, Zhang Y, et al. Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med. 2000 Oct 17;133(8):635–646. [PubMed]
  • HARRISON MH, SCHAJOWICZ F, TRUETA J. Osteoarthritis of the hip: a study of the nature and evolution of the disease. J Bone Joint Surg Br. 1953 Nov;35-B(4):598–626. [PubMed]
  • Westacott CI, Webb GR, Warnock MG, Sims JV, Elson CJ. Alteration of cartilage metabolism by cells from osteoarthritic bone. Arthritis Rheum. 1997 Jul;40(7):1282–1291. [PubMed]
  • Burr David B. The importance of subchondral bone in the progression of osteoarthritis. J Rheumatol Suppl. 2004 Apr;70:77–80. [PubMed]
  • Macfarlane DG, Buckland-Wright JC, Lynch J, Fogelman I. A study of the early and late 99technetium scintigraphic images and their relationship to symptoms in osteoarthritis of the hands. Br J Rheumatol. 1993 Nov;32(11):977–981. [PubMed]
  • Arnoldi CC. Vascular aspects of degenerative joint disorders. A synthesis. Acta Orthop Scand Suppl. 1994 Aug;261:1–82. [PubMed]
  • Ghosh P, Cheras PA. Vascular mechanisms in osteoarthritis. Best Pract Res Clin Rheumatol. 2001 Dec;15(5):693–709. [PubMed]
  • Haywood L, McWilliams DF, Pearson CI, Gill SE, Ganesan A, Wilson D, Walsh DA. Inflammation and angiogenesis in osteoarthritis. Arthritis Rheum. 2003 Aug;48(8):2173–2177. [PubMed]
  • Yamamoto T, Yamaguchi T, Lee KB, Bullough PG. A clinicopathologic study of osteonecrosis in the osteoarthritic hip. Osteoarthritis Cartilage. 2000 Jul;8(4):303–308. [PubMed]
  • Bergman AG, Willén HK, Lindstrand AL, Pettersson HT. Osteoarthritis of the knee: correlation of subchondral MR signal abnormalities with histopathologic and radiographic features. Skeletal Radiol. 1994 Aug;23(6):445–448. [PubMed]
  • Zanetti M, Bruder E, Romero J, Hodler J. Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings. Radiology. 2000 Jun;215(3):835–840. [PubMed]
  • Felson David T, McLaughlin Sara, Goggins Joyce, LaValley Michael P, Gale M Elon, Totterman Saara, Li Wei, Hill Catherine, Gale Daniel. Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med. 2003 Sep 2;139(5 Pt 1):330–336. [PubMed]
  • Imhof H, Breitenseher M, Kainberger F, Trattnig S. Degenerative joint disease: cartilage or vascular disease? Skeletal Radiol. 1997 Jul;26(7):398–403. [PubMed]
  • Simkin Peter A. Bone pain and pressure in osteoarthritic joints. Novartis Found Symp. 2004;260:179–279. [PubMed]
  • Monson RR, Hall AP. Mortality among arthritics. J Chronic Dis. 1976 Jul;29(7):459–467. [PubMed]
  • Hippisley-Cox Julia, Coupland Carol. Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis. BMJ. 2005 Jun 11;330(7504):1366–1366. [PMC free article] [PubMed]
  • Sonnenblick Edmund H. Differences between COX-2-specific inhibitors: clinical and economic implications. Am J Manag Care. 2002 Oct;8(15 Suppl):S428–S430. [PubMed]
  • Kadam UT, Jordan K, Croft PR. Clinical comorbidity in patients with osteoarthritis: a case-control study of general practice consulters in England and Wales. Ann Rheum Dis. 2004 Apr;63(4):408–414. [PMC free article] [PubMed]
  • Stürmer T, Sun Y, Sauerland S, Zeissig I, Günther KP, Puhl W, Brenner H. Serum cholesterol and osteoarthritis. The baseline examination of the Ulm Osteoarthritis Study. J Rheumatol. 1998 Sep;25(9):1827–1832. [PubMed]
  • Cerhan JR, Wallace RB, el-Khoury GY, Moore TE, Long CR. Decreased survival with increasing prevalence of full-body, radiographically defined osteoarthritis in women. Am J Epidemiol. 1995 Feb 1;141(3):225–234. [PubMed]
  • Haara MM, Manninen P, Kröger H, Arokoski JPA, Kärkkäinen A, Knekt P, Aromaa A, Heliövaara M. Osteoarthritis of finger joints in Finns aged 30 or over: prevalence, determinants, and association with mortality. Ann Rheum Dis. 2003 Feb;62(2):151–158. [PMC free article] [PubMed]
  • Sayer A Aihie, Poole J, Cox V, Kuh D, Hardy R, Wadsworth M, Cooper C. Weight from birth to 53 years: a longitudinal study of the influence on clinical hand osteoarthritis. Arthritis Rheum. 2003 Apr;48(4):1030–1033. [PubMed]
  • Aspden RM, Scheven BA, Hutchison JD. Osteoarthritis as a systemic disorder including stromal cell differentiation and lipid metabolism. Lancet. 2001 Apr 7;357(9262):1118–1120. [PubMed]
  • Doherty M. Risk factors for progression of knee osteoarthritis. Lancet. 2001 Sep 8;358(9284):775–776. [PubMed]
  • Dieppe P. Osteoarthritis: time to shift the paradigm. This includes distinguishing between severe disease and common minor disability. BMJ. 1999 May 15;318(7194):1299–1300. [PMC free article] [PubMed]
  • Cooper C, Snow S, McAlindon TE, Kellingray S, Stuart B, Coggon D, Dieppe PA. Risk factors for the incidence and progression of radiographic knee osteoarthritis. Arthritis Rheum. 2000 May;43(5):995–1000. [PubMed]
  • Dieppe P, Cushnaghan J, Young P, Kirwan J. Prediction of the progression of joint space narrowing in osteoarthritis of the knee by bone scintigraphy. Ann Rheum Dis. 1993 Aug;52(8):557–563. [PMC free article] [PubMed]
  • Kurunlahti M, Tervonen O, Vanharanta H, Ilkko E, Suramo I. Association of atherosclerosis with low back pain and the degree of disc degeneration. Spine (Phila Pa 1976) 1999 Oct 15;24(20):2080–2084. [PubMed]
  • Kokkonen Salla-Maarit, Kurunlahti Mauno, Tervonen Osmo, Ilkko Eero, Vanharanta Heikki. Endplate degeneration observed on magnetic resonance imaging of the lumbar spine: correlation with pain provocation and disc changes observed on computed tomography diskography. Spine (Phila Pa 1976) 2002 Oct 15;27(20):2274–2278. [PubMed]
  • Beattie Mary S, Lane Nancy E, Hung Yun-Yi, Nevitt Michael C. Association of statin use and development and progression of hip osteoarthritis in elderly women. J Rheumatol. 2005 Jan;32(1):106–110. [PubMed]
  • Watts Nelson. Bisphosphonates, statins, osteoporosis, and atherosclerosis. South Med J. 2002 Jun;95(6):578–582. [PubMed]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Group


Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


  • MedGen
    Related information in MedGen
  • PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...