Logo of annrheumdAnnals of the Rheumatic DiseasesVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
Ann Rheum Dis. 2001 Apr; 60(4): 420–422.
PMCID: PMC1753623

Type I collagen degradation does not diminish with RA disease duration

Abstract

OBJECTIVE—To assess the relation between type I collagen degradation and the duration of rheumatoid arthritis (RA).
METHODS—The serum concentrations of cross linked carboxyterminal telopeptide of type I collagen (ICTP) measured earlier in a community based series (90 patients) and a hospital based series (59 patients) were re-evaluated with reference to the duration of RA.
RESULTS—The serum ICTP showed a positive correlation with the duration of the disease in the hospital based series (rs=0.40, p<0.01) but not in the community based one (rs=0.18, p=0.10).
CONCLUSIONS—Type I collagen degradation predominantly reflecting pathological bone destruction does not seem to diminish in longlasting RA.



Full Text

The Full Text of this article is available as a PDF (70K).

Figures and Tables

Figure 1
Relation between serum carboxyterminal telopeptide of type I collagen (ICTP) and disease duration in two series of patients with rheumatoid arthritis: (A) a community based one (rs=0.18, p=0.10) and (B) a hospital based one (rs=0.40, p<0.01). ...

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Group

Formats:

Save items

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles
  • Substance
    Substance
    PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...